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We propose the Medial Skeletal Diagram, a novel skeletal representation that tackles the prevailing issues around skeleton sparsity and reconstruction accuracy in existing skeletal representations. Our approach augments the continuous…

Graphics · Computer Science 2024-10-04 Minghao Guo , Bohan Wang , Wojciech Matusik

As the only thiol-bearing amino acid, cysteine (Cys) residues in proteins have the reactive thiol side chain, which is susceptible to a series of post-translational modifications (PTMs). These PTMs participate in a wide range of biological…

Biomolecules · Quantitative Biology 2021-05-31 Yanzheng Meng , Lei Li

Recently a technique based on the interaction between adhesion proteins extracted from Streptococcus pyogenes, known as SpyRing, has been widely used to improve the thermal resilience of enzymes, the assembly of biostructures, cancer cell…

Biomolecules · Quantitative Biology 2022-04-06 Qi Gao , Dengming Ming

We introduce a broadly applicable technique to create nuclear spin singlet states in organic molecules and other many-atom systems. We employ a novel pulse sequence to produce a spin-lock induced crossing (SLIC) of the spin singlet and…

Quantum Physics · Physics 2013-10-30 Stephen J. DeVience , Ronald L. Walsworth , Matthew S. Rosen

Generative artificial intelligence has revolutionized the exploration of chemical space, yet a critical bottleneck remains that a substantial fraction of generated molecules is synthetically inaccessible. Current solutions, such as post-hoc…

Artificial Intelligence · Computer Science 2025-12-24 Junren Li , Luhua Lai

Extracellular recordings with multi-electrode arrays is one of the basic tools of contemporary neuroscience. These recordings are mostly used to monitor the activities, understood as sequences of emitted action potentials, of many…

Computational Engineering, Finance, and Science · Computer Science 2014-12-22 Christophe Pouzat , Georgios Is. Detorakis

The mode of action of proteins is to a large extent given by their ability to adopt different conformations. This is why imaging single biomolecules at atomic resolution is one of the ultimate goals of biophysics and structural biology. The…

Biological Physics · Physics 2012-09-27 Jean-Nicolas Longchamp , Tatiana Latychevskaia , Conrad Escher , Hans-Werner Fink

Chirality manifests across multiple scales, yielding unique phenomena that break mirror symmetry. In chiral materials, unexpectedly large spin-filtering or photogalvanic effects have been observed even in materials composed of light…

Machine-learning interatomic potentials (MLIPs) offer a powerful avenue for simulations beyond length and timescales of ab initio methods. Their development for investigation of mechanical properties and fracture, however, is far from…

We study the influence of a scanning nano-electrode on fluorescence excitation spectra of single terrylene molecules embedded in thin p-terphenyl films at cryogenic temperatures. We show that applied voltages less than 10 V can result in…

Chemical Physics · Physics 2010-09-17 Ilja Gerhardt , Gert Wrigge , Vahid Sandoghdar

Chirality pervades natural processes from the atomic to the cosmic scales, crucially impacting molecular chemistry and pharmaceutics. Traditional chirality sensing methods face challenges in sensitivity and efficiency, prompting the quest…

Structural, electronic, and chemical nanoscale modifications of transition metal dichalcogenide monolayers alter their optical properties, including the generation of single photon emitters. A key missing element for complete control is a…

Interactions of Poly (Ethylene Oxide) [PEO] and gamma irradiation of variable doses (1-30 kGy) on the thermal, crystalline and structural properties are investigated using DSC and FTIR technique. Two states of PEO, viz. powder (P-S-series)…

Materials Science · Physics 2014-11-24 Madhumita Mukhopadhyay , Mou Saha , Ruma Ray , Sujata Tarafdar

We experimentally investigate the chiral optical response of an individual nanostructure consisting of three equally sized spherical nanoparticles made of different materials and arranged in \ang{90} bent geometry. Placing the nanostructure…

Optics · Physics 2019-07-30 Sergey Nechayev , René Barczyk , Uwe Mick , Peter Banzer

Organic molecular crystals are appealing for next-generation optoelectronic applications, most notably due to their multiexciton generation process that can increase the efficiency of photovoltaic devices. However, a general understanding…

Materials Science · Physics 2021-11-01 Aaron R. Altman , Sivan Refaely-Abramson , Felipe H. da Jornada

Reversibility is of paramount importance in the correct representation of surface peeling in various physical settings, ranging from motility in nature, to gripping devices in robotic applications, and even to sliding of tectonic plates.…

Soft Condensed Matter · Physics 2021-07-06 Evelyne Ringoot , Thibault Roch , Jean-François Molinari , Thierry J. Massart , Tal Cohen

Molecules with unpaired spins (radicals) offer promising alternatives to closed-shell molecules as they are less limited regarding the spin statistics in their electroluminescence. Here, we combine scanning tunneling microscopy induced…

Mesoscale and Nanoscale Physics · Physics 2026-02-09 Vibhuti N. Rai , Christof Holzer , Carsten Rockstuhl , Wulf Wulfhekel , Lukas Gerhard

Rapid and repeated photon cycling has enabled precision metrology and the development of quantum information systems using a variety of atoms and simple molecules. Extending optical cycling to structurally complex molecules would provide…

We propose a theoretical model to describe the strain-induced linear electro-optic (Pockels) effect in centro-symmetric crystals. The general formulation is presented and the specific case of the strained silicon is investigated in detail…

Optics · Physics 2016-12-28 Costanza Lucia Manganelli , Paolo Pintus , Claudio Bonati

Colloidal particles can create reconfigurable nanomaterials, with applications such as color-changing, self-repairing, and self-regulating materials and reconfigurable drug delivery systems. However, top-down methods for manipulating…

Soft Condensed Matter · Physics 2024-07-26 Mark N. McDonald , Cameron K. Peterson , Douglas R. Tree
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