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Foundation models, including large language models (LLMs), are increasingly used for human-in-the-loop (HITL) cyber-physical systems (CPS) because foundation model-based AI agents can potentially interact with both the physical environments…

Artificial Intelligence · Computer Science 2026-04-14 Deeksha Prahlad , Daniel Fan , Hokeun Kim

In modern medicine, clinical diagnosis relies on the comprehensive analysis of primarily textual and visual data, drawing on medical expertise to ensure systematic and rigorous reasoning. Recent advances in large Vision-Language Models…

Artificial Intelligence · Computer Science 2025-07-03 Ziyue Wang , Junde Wu , Linghan Cai , Chang Han Low , Xihong Yang , Qiaxuan Li , Yueming Jin

Mental health disorders affect millions worldwide, and healthcare systems are increasingly overwhelmed by the volume of clinical data generated from electronic records, telemedicine platforms, and population-level screening programs. At the…

Artificial Intelligence · Computer Science 2026-05-14 Giuliano Lorenzoni , Paulo Alencar , Donald Cowan

Background: There is great interest in agentic LLMs, large language models that act as agents. Objectives: We review the growing body of work in this area and provide a research agenda. Methods: Agentic LLMs are LLMs that (1) reason, (2)…

Artificial Intelligence · Computer Science 2026-01-01 Aske Plaat , Max van Duijn , Niki van Stein , Mike Preuss , Peter van der Putten , Kees Joost Batenburg

Large Language Models (LLMs) have demonstrated impressive capabilities, yet their deployment in high-stakes domains is hindered by inherent limitations in trustworthiness, including hallucinations, instability, and a lack of transparency.…

Computation and Language · Computer Science 2025-10-21 David Peer , Sebastian Stabinger

When automating plan generation for a real-world sequential decision problem, the goal is often not to replace the human planner, but to facilitate an iterative reasoning and elicitation process, where the human's role is to guide the AI…

Artificial Intelligence · Computer Science 2026-04-10 Guilhem Fouilhé , Rebecca Eifler , Antonin Poché , Sylvie Thiébaux , Nicholas Asher

The emergence of large language models has catalyzed two distinct yet interconnected paradigms in artificial intelligence: standalone AI Agents and collaborative Agentic AI ecosystems. This comprehensive study establishes a definitive…

Artificial Intelligence · Computer Science 2025-06-17 Prashik Buddhaghosh Bansod

Recent advances in large language models (LLMs) have catalyzed the rise of autonomous AI agents capable of perceiving, reasoning, and acting in dynamic, open-ended environments. These large-model agents mark a paradigm shift from static…

Artificial Intelligence · Computer Science 2025-07-01 Hang Su , Jun Luo , Chang Liu , Xiao Yang , Yichi Zhang , Yinpeng Dong , Jun Zhu

Recent progress in multimodal large language models (MLLMs) has demonstrated promising performance on medical benchmarks and in preliminary trials as clinical assistants. Yet, our pilot audit of diagnostic cases uncovers a critical failure…

Artificial Intelligence · Computer Science 2025-09-30 Hongjun Liu , Yinghao Zhu , Yuhui Wang , Yitao Long , Zeyu Lai , Lequan Yu , Chen Zhao

Existing multimodal reasoning models and frameworks suffer from fundamental architectural limitations: most lack the human-like ability to autonomously explore diverse reasoning pathways-whether in direct inference, tool-driven visual…

Artificial Intelligence · Computer Science 2025-12-15 Yifu Guo , Zishan Xu , Zhiyuan Yao , Yuquan Lu , Jiaye Lin , Sen Hu , Zhenheng Tang , Huacan Wang , Ronghao Chen

Agentic systems enable the intelligent use of research tooling, augmenting a researcher's ability to investigate and propose novel solutions to existing problems. Within Additive Manufacturing (AM), alloy selection and evaluation remains a…

Artificial Intelligence · Computer Science 2026-01-27 Peter Pak , Achuth Chandrasekhar , Amir Barati Farimani

The rapid advancement of artificial intelligence, particularly autonomous agentic systems based on Large Language Models (LLMs), presents new opportunities to accelerate drug discovery by improving in-silico modeling and reducing dependence…

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

In this paper we suggest an architecture for a software agent which operates a physical device and is capable of making observations and of testing and repairing the device's components. We present simplified definitions of the notions of…

Artificial Intelligence · Computer Science 2007-05-23 Marcello Balduccini , Michael Gelfond

The evolution of agentic systems represents a significant milestone in artificial intelligence and modern software systems, driven by the demand for vertical intelligence tailored to diverse industries. These systems enhance business…

Multiagent Systems · Computer Science 2025-01-03 Fouad Bousetouane

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

Language model (LM) agents are increasingly used as autonomous decision-makers which need to actively gather information to guide their decisions. A crucial cognitive skill for such agents is the efficient exploration and understanding of…

Artificial Intelligence · Computer Science 2025-10-07 Anthony GX-Chen , Dongyan Lin , Mandana Samiei , Doina Precup , Blake A. Richards , Rob Fergus , Kenneth Marino

Traditional AI-based healthcare systems often rely on single-modal data, limiting diagnostic accuracy due to incomplete information. However, recent advancements in foundation models show promising potential for enhancing diagnosis…

Artificial Intelligence · Computer Science 2025-03-24 Sihan Wang , Suiyang Jiang , Yibo Gao , Boming Wang , Shangqi Gao , Xiahai Zhuang

A wide range of real-world applications is characterized by their symbolic nature, necessitating a strong capability for symbolic reasoning. This paper investigates the potential application of Large Language Models (LLMs) as symbolic…

Computation and Language · Computer Science 2024-01-18 Meng Fang , Shilong Deng , Yudi Zhang , Zijing Shi , Ling Chen , Mykola Pechenizkiy , Jun Wang

The aim of this study is to formally express awareness for modeling practical agent communication. The notion of awareness has been proposed as a set of propositions for each agent, to which he/she pays attention, and has contributed to…

Multiagent Systems · Computer Science 2024-02-13 Yudai Kubono , Teeradaj Racharak , Satoshi Tojo
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