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Conventional approaches for simulating steady-state distributions of particles under diffusive and advective transport at high P\'eclet numbers involve solving the diffusion and advection equations in at least two dimensions. Here, we…

We assess experimentally the ability of a simple flow-based sorting device, recently proposed numerically by [Zhu et al., Soft Matter, 2014, 10, 7705-7711], to separate capsules according to their stiffness. The device consists of a single…

Soft Condensed Matter · Physics 2021-01-01 Edgar Haner , Doriane Vesperini , Anne-Virginie Salsac , Anne Le Goff , Anne Juel

Optimizing the energy efficiency of driving processes provides valuable insights into the underlying physics and is of crucial importance for numerous applications, from biological processes to the design of machines and robots. Knowledge…

Soft Condensed Matter · Physics 2024-04-02 Sarah A. M. Loos , Samuel Monter , Felix Ginot , Clemens Bechinger

Membrane ultrafiltration (UF) is a pressure driven process allowing for the separation and enrichment of protein solutions and dispersions of nanosized microgel particles. The permeate flux and the near-membrane concentration-polarization…

Soft Condensed Matter · Physics 2015-05-19 Rafael Roa , Emiliy K. Zholkovskiy , Gerhard Nägele

Ferrohydrodynamic microfluidics relies on magnetic field gradients to manipulate diamagnetic particles in ferrofluid-filled microenvironments. It has emerged as a promising tool for label-free manipulation of bioparticles, including their…

Systems and Control · Electrical Eng. & Systems 2025-11-03 Yuhao Zhang , Yong Teng , Kenan Song , Xianqiao Wang , Xianyan Chen , Yuhua Liu , Yiping Zhao , He Li , Leidong Mao , Yang Liu

A new optimized quasihelically symmetric configuration is described that has the desir-able properties of improved energetic particle confinement, reduced turbulent transportby 3D shaping, and non-resonant divertor capabilities. The…

Microfluidic channels are integral to biomedical technology and process engineering, offering versatility in handling fluids with complex properties, often a combination of viscous and elastic attributes. Despite significant advancements in…

Soft Condensed Matter · Physics 2025-09-29 Sampad Laha , Siddhartha Mukherjee , Suman Chakraborty

Particles traveling through inertial microfluidic devices migrate to focusing streamlines. We present a numerical method that calculates migration velocities of particles in inertial microfluidic channels of arbitrary cross section by…

Fluid Dynamics · Physics 2022-10-19 Samuel Christensen , Raymond Chu , Christopher R Anderson , Marcus Roper

In inertial microfluidics colloidal particles in a Poiseuille flow experience the Segr\'e-Silberberg lift force, which drives them to specific positions in the channel cross section. Due to the Saffman effect an external force applied along…

Soft Condensed Matter · Physics 2020-06-15 Felix Rühle , Christian Schaaf , Holger Stark

An important step in diagnostics is the isolation of specific cells and microorganisms of interest from blood. Since such bioparticles are often present at very low concentrations, throughput needs to be as high as possible. In addition, to…

Soft Condensed Matter · Physics 2019-07-31 Stefan H. Holm , Zunmin Zhang , Jason P. Beech , Gerhard Gompper , Dmitry A. Fedosov , Jonas O. Tegenfeldt

We report the discovery of a mixed orientational structure in the quasi-one-dimensional fluid of hard non-spherical bodies with the exact calculation of the thermodynamic and structural quantities using the transfer operator method. The…

Soft Condensed Matter · Physics 2025-10-13 Sakineh Mizani , Martin Oettel , Péter Gurin , Szabolcs Varga

Cell spheroids are in vitro multicellular model systems that mimic the crowded micro-environment of biological tissues. Their mechanical characterization can provide valuable insights in how single-cell mechanics and cell-cell interactions…

Quantitative Methods · Quantitative Biology 2022-11-21 R. C. Boot , A. Roscani , L. van Buren , S. Maity , G. H. Koenderink , P. E. Boukany

The manipulation and control of microparticles through non-intrusive methods is pivotal in biomedical applications such as cell sorting and cell focusing. Although several experimental and numerical studies have been dedicated to single…

Fluid Dynamics · Physics 2023-12-20 Giancarlo Esposito , Gaetano D'Avino , Massimiliano Maria Villone

Recent advance in nanotechnology has led to rapid advances in nanofluidics, which has been established as a reliable means for a wide variety of applications, including molecular separation, detection, crystallization and biosynthesis.…

Quantitative Methods · Quantitative Biology 2015-03-03 Jin Kyoung Park , Kelin Xia , Guo-Wei We

Particle smoothing methods are used for inference of stochastic processes based on noisy observations. Typically, the estimation of the marginal posterior distribution given all observations is cumbersome and computational intensive. In…

Machine Learning · Computer Science 2017-05-24 H. -Ch. Ruiz , H. J. Kappen

Digital microfluidic (DMF) biochips are now being extensively used to automate several biochemical laboratory protocols such as clinical analysis, point-of-care diagnostics, and polymerase chain reaction (PCR). In many biological assays,…

Emerging Technologies · Computer Science 2013-07-05 Sukanta Bhattacharjee , Ansuman Banerjee , Tsung-Yi Ho , Krishnendu Chakrabarty , Bhargab B. Bhattacharya

Most parallel applications suffer from load imbalance, a crucial performance degradation factor. In particle simulations, this is mainly due to the migration of particles between processing elements, which eventually gather unevenly and…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-08-26 Anthony Boulmier , Nabil Abdennadher , Bastien Chopard

Particle-In-Cell codes are widely used for plasma physics simulations. It is often the case that particles within a computational cell need to be split to improve the statistics or, in the case of non-uniform meshes, to avoid the…

Computational Physics · Physics 2021-04-22 Roch Smets , Nicolas Aunais , ANdrea Ciardi , Matthieu Drouin , Martin Campos-Pino , Philip Deegan

Particle Flow Filters perform the measurement update by moving particles to a different location rather than modifying the particles' weight based on the likelihood. Their movement (flow) is dictated by a drift term, which continuously…

Computational Engineering, Finance, and Science · Computer Science 2025-07-04 Simone Servadio

We study suspensions of oblate rigid particles in a viscous fluid for different values of the particle volume fractions. Direct numerical simulations have been performed using a direct-forcing immersed boundary method to account for the…

Fluid Dynamics · Physics 2021-02-23 M. Niazi Ardekani , P. Costa , W. -P. Breugem , F. Picano , L. Brandt