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The integration of Agentic AI into scientific discovery marks a new frontier in research automation. These AI systems, capable of reasoning, planning, and autonomous decision-making, are transforming how scientists perform literature…

Computation and Language · Computer Science 2025-03-13 Mourad Gridach , Jay Nanavati , Khaldoun Zine El Abidine , Lenon Mendes , Christina Mack

We introduce PaSa, an advanced Paper Search agent powered by large language models. PaSa can autonomously make a series of decisions, including invoking search tools, reading papers, and selecting relevant references, to ultimately obtain…

Information Retrieval · Computer Science 2025-05-28 Yichen He , Guanhua Huang , Peiyuan Feng , Yuan Lin , Yuchen Zhang , Hang Li , Weinan E

Artificial intelligence systems for scientific discovery have demonstrated remarkable potential, yet existing approaches remain largely proprietary and operate in batch-processing modes requiring hours per research cycle, precluding…

Artificial Intelligence · Computer Science 2026-01-28 Lukas Weidener , Marko Brkić , Mihailo Jovanović , Ritvik Singh , Chiara Baccin , Emre Ulgac , Alex Dobrin , Aakaash Meduri

AI agents hold the potential to revolutionize scientific productivity by automating literature reviews, replicating experiments, analyzing data, and even proposing new directions of inquiry; indeed, there are now many such agents, ranging…

Artificial intelligence systems are transforming scientific discovery by accelerating specific research tasks, from protein structure prediction to materials design, yet remain confined to narrow domains requiring substantial human…

Artificial Intelligence · Computer Science 2026-01-30 Gabrielle Wehr , Reuben Rideaux , Amaya J. Fox , David R. Lightfoot , Jason Tangen , Jason B. Mattingley , Shane E. Ehrhardt

We introduce Paper2Agent, an automated framework that converts research papers into AI agents. Paper2Agent transforms research output from passive artifacts into active systems that can accelerate downstream use, adoption, and discovery.…

Artificial Intelligence · Computer Science 2025-10-17 Jiacheng Miao , Joe R. Davis , Yaohui Zhang , Jonathan K. Pritchard , James Zou

In the rapidly evolving field of data science, efficiently navigating the expansive body of academic literature is crucial for informed decision-making and innovation. This paper presents an enhanced Retrieval-Augmented Generation (RAG)…

Information Retrieval · Computer Science 2025-05-15 Ahmet Yasin Aytar , Kemal Kilic , Kamer Kaya

We present the AI Cosmologist, an agentic system designed to automate cosmological/astronomical data analysis and machine learning research workflows. This implements a complete pipeline from idea generation to experimental evaluation and…

Instrumentation and Methods for Astrophysics · Physics 2025-04-07 Adam Moss

Large language models are moving scientific research from text assistance toward agentic workflows, yet biological research requires strong object validation, methodological suitability, reproducibility, and auditability. Prompt…

Quantitative Methods · Quantitative Biology 2026-05-25 Zhenyu Ma , Yuyang Song , Chunyi Yang , Jingyi Zhu , Limei Xu , Min Xiao , Xukai Jiang

One of the grand challenges of artificial general intelligence is developing agents capable of conducting scientific research and discovering new knowledge. While frontier models have already been used as aides to human scientists, e.g. for…

Artificial Intelligence · Computer Science 2024-09-04 Chris Lu , Cong Lu , Robert Tjarko Lange , Jakob Foerster , Jeff Clune , David Ha

We introduce AEGIS, A holistic benchmark for Evaluating forensic analysis of AI-Generated academic ImageS. Compared to existing benchmarks, AEGIS features three key advances: (1) Domain-Specific Complexity: covering seven academic…

Automating science laboratories enables faster, safer, more accurate, and more reproducible execution of protocols, accelerating the discovery and testing of new materials, drugs, and more. However, setting up and running autonomous labs…

Artificial Intelligence · Computer Science 2026-05-19 Angelos Angelopoulos , James F. Cahoon , Ron Alterovitz

AI is increasingly playing a pivotal role in transforming how scientific discoveries are made. We introduce The AI Scientist-v2, an end-to-end agentic system capable of producing the first entirely AI generated peer-review-accepted workshop…

Artificial Intelligence · Computer Science 2025-04-14 Yutaro Yamada , Robert Tjarko Lange , Cong Lu , Shengran Hu , Chris Lu , Jakob Foerster , Jeff Clune , David Ha

The rapid expansion of scholarly literature presents significant challenges in synthesizing comprehensive, high-quality academic surveys. Recent advancements in agentic systems offer considerable promise for automating tasks that…

Digital Libraries · Computer Science 2025-11-25 Zi Wang , Xingqiao Wang , Sangah Lee , Xiaowei Xu

As many of us in the information retrieval (IR) research community know and appreciate, search is far from being a solved problem. Millions of people struggle with tasks on search engines every day. Often, their struggles relate to the…

Information Retrieval · Computer Science 2024-04-04 Ryen W. White

This paper details two novel frameworks for developing autonomous, agentic AI in scientific workflows. Both systems leverage a hybrid Local Body, Remote Brain architecture via Google Colab, utilizing Python-based local orchestrators to…

Artificial Intelligence · Computer Science 2026-05-27 Judy Fox , Geoffrey Fox

Scientific progress in Earth science depends on integrating data across the planet's interconnected spheres. However, the accelerating volume and fragmentation of multi-sphere knowledge and data have surpassed human analytical capacity.…

AI agents have the potential to aid users on a variety of consequential tasks, including conducting scientific research. To spur the development of useful agents, we need benchmarks that are challenging, but more crucially, directly…

Computation and Language · Computer Science 2024-09-18 Zachary S. Siegel , Sayash Kapoor , Nitya Nagdir , Benedikt Stroebl , Arvind Narayanan

Academic citation integrity faces persistent challenges, with research indicating 20% of citations contain errors and manual verification requiring months of expert time. This paper presents a novel AI-powered methodology for systematic,…

Digital Libraries · Computer Science 2025-11-10 L. J. Janse van Rensburg

Artificial intelligence (AI) agents are emerging as transformative tools in drug discovery, with the ability to autonomously reason, act, and learn through complicated research workflows. Building on large language models (LLMs) coupled…

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