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Two-Photon Microscopy (TPM) can provide three-dimensional morphological and functional contrast in vivo. Through proper staining, TPM can be utilized to create virtual, H&E equivalent images and thus can improve throughput in…

Small-pitch 3D silicon pixel detectors have been investigated as radiation-hard candidates for the innermost layers of the HL-LHC pixel detector upgrades. Prototype 3D sensors with pixel sizes of 50$\times$50 and 25$\times$100 $\mu$m$^{2}$…

Instrumentation and Detectors · Physics 2018-09-18 J. Lange , G. Giannini , S. Grinstein , M. Manna , G. Pellegrini , D. Quirion , S. Terzo , D. Vázquez Furelos

We have been developing a monolithic active pixel sensor, ``XRPIX``, for the Japan led future X-ray astronomy mission ``FORCE`` observing the X-ray sky in the energy band of 1-80 keV with angular resolution of better than 15``. XRPIX is an…

The Large Hadron Collider (LHC) at CERN will undergo an upgrade in order to increase its luminosity to $7.5 \times 10^{34}$ cm$^{-2}$s$^{-1}$. The increased luminosity during this High-Luminosity running phase (HL-LHC), starting around…

Instrumentation and Detectors · Physics 2023-09-04 The Tracker Group of the CMS Collaboration

Recent advancements in particle physics demand pixel detectors that can withstand increased luminosity in the future collider experiments. In response, MALTA, a novel monolithic active pixel detector, has been developed with a cutting-edge…

Instrumentation and Detectors · Physics 2025-02-05 Anusree Vijay , Prafulla Kumar Behera , Theertha Chembakan , Ganapati Dash

The ALICE Inner Tracking System has been recently upgraded to a full silicon detector consisting entirely of MAPS, arranged in seven concentric layers around the LHC beam pipe. Further ahead, during the LHC Long Shutdown 3, the ALICE…

Instrumentation and Detectors · Physics 2022-09-21 Bogdan-Mihail Blidaru

Monolithic active pixel sensors (MAPS) are now well established as a technology for tracking charged particles, especially when low material budget is desirable. For such applications, sensors focus on spatial resolution and pixels with…

Instrumentation and Detectors · Physics 2022-09-28 W. Ren , J. Baudot , L. Federici , C. Finck , C. Hu-Guo , M. Kachel , C. -A. Reidel , C. Schui , R. Sefri , E. Spiriti , U. Weber , Y. Zhao

Ultra-high dose rate radiation therapy (FLASH) based on proton irradiation is of major interest for cancer treatments but creates new challenges for dose monitoring. Amorphous hydrogenated silicon is known to be one of the most…

The significant optical and size benefits of using a curved focal surface for imaging systems have been well studied yet never brought to market for lack of a high-quality, mass-producible, curved image sensor. In this work we demonstrate…

Advances in laser technology have driven discoveries in atomic, molecular, and optical (AMO) physics and emerging applications, from quantum computers with cold atoms or ions, to quantum networks with solid-state color centers. This…

Optoelectronic functionalities of photodection and light harnessing rely on the band-to-band excitation of semiconductors, thus the spectral response of the devices is dictated and limited by their bandgap. A novel approach, free from this…

Mesoscale and Nanoscale Physics · Physics 2014-06-12 F. Pelayo García de Arquer , Agustín Mihi , Gerasimos Konstantatos

Computational analysis of multiplexed immunofluorescence histology data is emerging as an important method for understanding the tumour micro-environment in cancer. This work presents HEMIT, a dataset designed for translating Hematoxylin…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Chang Bian , Beth Philips , Tim Cootes , Martin Fergie

MiniCACTUS-v2 is a monolithic sensor prototype designed in LF 150 nm CMOS process for time tagging of individual Minimum Ionizing Particles with an accuracy better than 100 ps. The sensing element is a deep n-well/p-substrate diode without…

Instrumentation and Detectors · Physics 2026-02-24 Y. Degerli , R. Aleksan , R. Casanova , Y. Gan , S. Grinstein , F. Guilloux , A. Hanlon , T. Hemperek , J. P. Meyer , J. Pinol , P. Schwemling , E. Vilella

Many IR datasets are taken with two dithers per filter, complicating the automated recognition of pixels with unstable response. Much data from the HST cameras NICMOS and WFC3 IR fall into this category, and future JWST and WFIRST data are…

Instrumentation and Methods for Astrophysics · Physics 2018-08-08 Miles Currie , David Rubin

A high sensitivity atom flux sensor based on atomic absorption spectroscopy has been designed and implemented to control electron beam evaporators and effusion cells in a molecular beam epitaxy system. Using a high-resolution spectrometer…

Materials Science · Physics 2015-06-19 Y. Du , T. C. Droubay , A. V. Liyu , G. Li , S. A. Chambers

Diamond has been developed as a material for the detection of charged particles by ionization. Its radiation hardness makes it an attractive material for detectors operated in a harsh radiation environment e.g. close to a particle beam as…

Instrumentation and Detectors · Physics 2009-02-09 M. Mathes , M. Cristinziani , H. Kagan , S. Smith , W. Trischuk , J. Velthuis , N. Wermes

The planned luminosity increase at the Large Hadron Collider in the coming years has triggered interest in the use of the particles' time of arrival as additional information in specialized detectors to mitigate the impact of pile-up. The…

Monolithic pixel detectors combine readout electronics and sensor in a single entity of silicon, which simplifies the production procedure and lowers the material budget compared to conventional hybrid pixel detector concepts. Benefiting…

The VOXES project's goal is to realize the first prototype of a high resolution and high precision X-ray spectrometer for diffused sources, using Highly Annealed Pyrolitic Graphite (HAPG) crystals combined with precision position detectors.…

Instrumentation and Detectors · Physics 2019-03-08 A. Scordo , H. Shi , C. Curceanu , M. Miliucci , F. Sirghi , J. Zmeskal

The Silicon-On-Insulator PIXel (SOIPIX) detector is a unique monolithic structure imaging device currently being by the SOIPIX group, led by the High Energy Accelerator Research Organization (KEK). Our detector team at the KEK Photon…

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