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Related papers: Memorization in Large Language Models in Medicine:…

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Large language models (LLMs) have been shown to memorize and reproduce content from their training data, raising significant privacy concerns, especially with web-scale datasets. Existing methods for detecting memorization are primarily…

Cryptography and Security · Computer Science 2026-01-07 Zhenpeng Wu , Jian Lou , Zibin Zheng , Chuan Chen

Although large language models excel across many tasks, they can memorise training data and thereby expose private or copyrighted text. Most defences target the pre-training stage, leaving memorisation during fine-tuning, especially for…

Computation and Language · Computer Science 2025-10-14 Dean L. Slack , Noura Al Moubayed

Large language models (LMs) have rapidly become a mainstay in Natural Language Processing. These models are known to acquire rich linguistic knowledge from training on large amounts of text. In this paper, we investigate if pre-training on…

Computation and Language · Computer Science 2022-10-25 Avinash Madasu , Shashank Srivastava

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Catastrophic forgetting is a significant challenge in continual learning, in which a model loses prior knowledge when it is fine-tuned on new tasks. This problem is particularly critical for large language models (LLMs) undergoing continual…

Computation and Language · Computer Science 2025-09-03 Ege Süalp , Mina Rezaei

AI models present a wide range of applications in the field of medicine. However, achieving optimal performance requires access to extensive healthcare data, which is often not readily available. Furthermore, the imperative to preserve…

Genomic language models (GLMs) have emerged as powerful tools for learning representations of DNA sequences, enabling advances in variant prediction, regulatory element identification, and cross-task transfer learning. However, as these…

Machine Learning · Computer Science 2026-03-11 Alexander Nemecek , Wenbiao Li , Xiaoqian Jiang , Jaideep Vaidya , Erman Ayday

Large Language Models (LLMs) have shown greatly enhanced performance in recent years, attributed to increased size and extensive training data. This advancement has led to widespread interest and adoption across industries and the public.…

Computation and Language · Computer Science 2024-06-19 Victoria Smith , Ali Shahin Shamsabadi , Carolyn Ashurst , Adrian Weller

Adapting general large language models (LLMs) to specialized domains presents great challenges due to varied data distributions. This adaptation typically requires continual pre-training on massive domain-specific corpora to facilitate…

Computation and Language · Computer Science 2024-07-16 Jinhao Jiang , Junyi Li , Wayne Xin Zhao , Yang Song , Tao Zhang , Ji-Rong Wen

Large language models (LLMs) have performed well across various clinical natural language processing tasks, despite not being directly trained on electronic health record (EHR) data. In this work, we examine how popular open-source LLMs…

Computation and Language · Computer Science 2025-05-26 Furong Jia , David Sontag , Monica Agrawal

Existing Large Language Models (LLMs) usually remain static after deployment, which might make it hard to inject new knowledge into the model. We aim to build models containing a considerable portion of self-updatable parameters, enabling…

Computation and Language · Computer Science 2024-05-28 Yu Wang , Yifan Gao , Xiusi Chen , Haoming Jiang , Shiyang Li , Jingfeng Yang , Qingyu Yin , Zheng Li , Xian Li , Bing Yin , Jingbo Shang , Julian McAuley

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

The discourse on privacy risks in Large Language Models (LLMs) has disproportionately focused on verbatim memorization of training data, while a constellation of more immediate and scalable privacy threats remain underexplored. This…

Cryptography and Security · Computer Science 2025-10-03 Niloofar Mireshghallah , Tianshi Li

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

In recent years, Large Language Models (LLMs) have become widely used in medical applications, such as clinical decision support, medical education, and medical question answering. Yet, these models are often English-centric, limiting their…

Computation and Language · Computer Science 2026-02-06 Chaimae Abouzahir , Congbo Ma , Nizar Habash , Farah E. Shamout

To produce accurate predictions, language models (LMs) must balance between generalization and memorization. Yet, little is known about the mechanism by which transformer LMs employ their memorization capacity. When does a model decide to…

Computation and Language · Computer Science 2023-02-14 Adi Haviv , Ido Cohen , Jacob Gidron , Roei Schuster , Yoav Goldberg , Mor Geva

Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

Computation and Language · Computer Science 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

Large language models, trained on massive corpora, are prone to verbatim memorization of training data, creating significant privacy and copyright risks. While previous works have proposed various definitions for memorization, many exhibit…

Computation and Language · Computer Science 2025-11-27 Trung Cuong Dang , David Mohaisen