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The surface properties of solid-state materials often dictate their functionality, especially for applications where nanoscale effects become important. The relevant surface(s) and their properties are determined, in large part, by the…

Materials Science · Physics 2024-03-19 Kyle Noordhoek , Christopher J. Bartel

Biomolecular condensates are small droplets forming spontaneously in biological cells via phase separation. They play a role in many cellular processes, but it is unclear how cells control them. Cellular regulation often relies on…

Soft Condensed Matter · Physics 2024-03-15 Jan Kirschbaum , David Zwicker

Our world is ambiguous and this is reflected in the data we use to train our algorithms. This is particularly true when we try to model natural processes where collected data is affected by noisy measurements and differences in measurement…

Machine Learning · Computer Science 2023-07-19 Jörg K. H. Franke , Frederic Runge , Frank Hutter

The applicability of computational and dynamical systems models to organisms is scrutinized, using examples from developmental biology and cognition. Developmental morphogenesis is dependent on the inherent material properties of developing…

Neurons and Cognition · Quantitative Biology 2023-10-24 Stuart A. Newman

Algorithms based on deep network models are being used for many pattern recognition and decision-making tasks in robotics and AI. Training these models requires a large labeled dataset and considerable computational resources, which are not…

Artificial Intelligence · Computer Science 2022-01-26 Mohan Sridharan , Tiago Mota

Learning and inferring features that generate sensory input is a task continuously performed by cortex. In recent years, novel algorithms and learning rules have been proposed that allow neural network models to learn such features from…

Neurons and Cognition · Quantitative Biology 2021-04-13 Yasser Roudi , Graham Taylor

In complex inferential tasks like question answering, machine learning models must confront two challenges: the need to implement a compositional reasoning process, and, in many applications, the need for this reasoning process to be…

Computer Vision and Pattern Recognition · Computer Science 2019-03-08 Ronghang Hu , Jacob Andreas , Trevor Darrell , Kate Saenko

Biomolecular condensates form on timescales of seconds in cells upon environmental or compositional changes. Condensate formation is thus argued to act as a mechanism for sensing such changes and quickly initiating downstream processes,…

Subcellular Processes · Quantitative Biology 2025-12-09 Henry Alston , Mason Rouches , Arvind Murugan , Aleksandra M. Walczak , Thierry Mora

Scientific machine learning (SciML) increasingly requires models that capture multimodal conditional uncertainty arising from ill-posed inverse problems, multistability, and chaotic dynamics. While recent work has favored highly expressive…

Machine Learning · Computer Science 2026-02-03 Leonardo Ferreira Guilhoto , Akshat Kaushal , Paris Perdikaris

The objective of this paper is to design novel multi-layer neural network architectures for multiscale simulations of flows taking into account the observed data and physical modeling concepts. Our approaches use deep learning concepts…

Numerical Analysis · Mathematics 2018-06-14 Yating Wang , Siu Wun Cheung , Eric T. Chung , Yalchin Efendiev , Min Wang

In recent years, storing large volumes of data on distributed devices has become commonplace. Applications involving sensors, for example, capture data in different modalities including image, video, audio, GPS and others. Novel algorithms…

Machine Learning · Computer Science 2021-02-10 Haimonti Dutta , Nitin Nataraj , Saurabh Amarnath Mahindre

Recent efforts have shown machine learning to be useful for the prediction of nonlinear fluid dynamics. Predictive accuracy is often a central motivation for employing neural networks, but the pattern recognition central to the network…

Fluid Dynamics · Physics 2022-08-23 Shizheng Wen , Michael W. Lee , Kai M. Kruger Bastos , Earl H. Dowell

Complex systems are often driven by higher-order interactions among multiple units, naturally represented as hypergraphs. Understanding dependency structures within these hypergraphs is crucial for understanding and predicting the behavior…

Social and Information Networks · Computer Science 2025-05-29 John Hood , Caterina De Bacco , Aaron Schein

Phase separation drives the formation of biomolecular condensates in cells, which comprise many components and sometimes possess multiple phases. The equilibrium physics of phase separation is well understood, but many components in…

Soft Condensed Matter · Physics 2025-08-14 Yicheng Qiang , Chengjie Luo , David Zwicker

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

The cellular environment, characterized by its intricate composition and spatial organization, hosts a variety of organelles, ranging from membrane-bound ones to membraneless structures that are formed through liquid-liquid phase…

Soft Condensed Matter · Physics 2026-03-09 Gregor Häfner , Marcus Müller

Natural physical, chemical, and biological dynamical systems are often complex, with heterogeneous components interacting in diverse ways. We show how simple graph neural networks can be designed to jointly learn the interaction rules and…

Cognition is the process of knowing. As carried out by a dynamical system, it is the process by which the system absorbs information into its state. A complex network of agents cognizes knowledge about its environment, internal dynamics and…

Multiagent Systems · Computer Science 2022-07-13 Jack Hall

In bacterial populations, cells are able to cooperate in order to yield complex collective functionalities. Interest in population-level cellular behaviour is increasing, due to both our expanding knowledge of the underlying biological…

Multiagent Systems · Computer Science 2012-11-07 Angel Goni-Moreno , Martyn Amos

Despite deep-learning being state-of-the-art for data-driven model predictions, it has not yet found frequent application in ecology. Given the low sample size typical in many environmental research fields, the default choice for the…

Applications · Statistics 2022-09-29 Marieke Wesselkamp , Niklas Moser , Maria Kalweit , Joschka Boedecker , Carsten F. Dormann