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Early detection of Alzheimer disease is crucial for deploying interventions and slowing the disease progression. A lot of machine learning and deep learning algorithms have been explored in the past decade with the aim of building an…

Heterogeneity of brain diseases is a challenge for precision diagnosis/prognosis. We describe and validate Smile-GAN (SeMI-supervised cLustEring-Generative Adversarial Network), a novel semi-supervised deep-clustering method, which dissects…

Multimodal neuroimage can provide complementary information about the dementia, but small size of complete multimodal data limits the ability in representation learning. Moreover, the data distribution inconsistency from different…

Structural magnetic resonance imaging (sMRI) can identify subtle brain changes due to its high contrast for soft tissues and high spatial resolution. It has been widely used in diagnosing neurological brain diseases, such as Alzheimer…

In recent years, many papers have reported state-of-the-art performance on Alzheimer's Disease classification with MRI scans from the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset using convolutional neural networks. However,…

\textbf{Objective:} Alzheimer's disease (AD) is the most prevalent form of dementia worldwide, encompassing a prodromal stage known as Mild Cognitive Impairment (MCI), where patients may either progress to AD or remain stable. The objective…

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

This work validates the generalizability of MRI-based classification of Alzheimer's disease (AD) patients and controls (CN) to an external data set and to the task of prediction of conversion to AD in individuals with mild cognitive…

Detection of Alzheimer's Disease (AD) from neuroimaging data such as MRI through machine learning has been a subject of intense research in recent years. Recent success of deep learning in computer vision has progressed such research…

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

Implicit neural representations (INRs) have emerged as a powerful paradigm for medical imaging via physics-informed unsupervised learning. Classical INRs optimize an entire network from scratch for each subject, leading to inefficient…

This study introduces a deep learning framework for the inferential exploration of latent representations in 3D brain MRI, leveraging a simple convolutional autoencoder with a hierarchical encoder and a compact latent space. Trained on…

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

The uncertainty of clinical examinations frequently leads to irregular observation intervals in longitudinal imaging data, posing challenges for modeling disease progression.Most existing imaging-based disease prediction models operate in…

Over the past decade, machine learning techniques especially predictive modeling and pattern recognition in biomedical sciences from drug delivery system to medical imaging has become one of the important methods which are assisting…

With the increasing incidence of neurodegenerative diseases such as Alzheimer's Disease (AD), there is a need for further research that enhances detection and monitoring of the diseases. We present MORPHADE (Morphological Autoencoders for…

Deep unsupervised representation learning has recently led to new approaches in the field of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these works is to learn a model of normal anatomy by learning to…

Convolutional neural networks (CNN) have become a powerful tool for detecting patterns in image data. Recent papers report promising results in the domain of disease detection using brain MRI data. Despite the high accuracy obtained from…

Deep Convolutional Neural Networks (CNNs) are becoming prominent models for semi-automated diagnosis of Alzheimer's Disease (AD) using brain Magnetic Resonance Imaging (MRI). Although being highly accurate, deep CNN models lack transparency…