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Nuclei segmentation is a fundamental but challenging task in the quantitative analysis of histopathology images. Although fully-supervised deep learning-based methods have made significant progress, a large number of labeled images are…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Xinyi Yu , Guanbin Li , Wei Lou , Siqi Liu , Xiang Wan , Yan Chen , Haofeng Li

In semantic segmentation, generalizing a visual system to both seen categories and novel categories at inference time has always been practically valuable yet challenging. To enable such functionality, existing methods mainly rely on either…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Yuhuan Yang , Chaofan Ma , Chen Ju , Fei Zhang , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Multiple instance learning (MIL) has shown significant promise in histopathology whole slide image (WSI) analysis for cancer diagnosis and prognosis. However, the inherent spatial heterogeneity of WSIs presents critical challenges, as…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Junjian Li , Jin Liu , Hulin Kuang , Hailin Yue , Mengshen He , Jianxin Wang

Nuclei segmentation is a fundamental task that is critical for various computational pathology applications including nuclei morphology analysis, cell type classification, and cancer grading. Conventional vision-based methods for nuclei…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Faisal Mahmood , Daniel Borders , Richard Chen , Gregory N. McKay , Kevan J. Salimian , Alexander Baras , Nicholas J. Durr

Image segmentation is a fundamental and challenging problem in computer vision with applications spanning multiple areas, such as medical imaging, remote sensing, and autonomous vehicles. Recently, convolutional neural networks (CNNs) have…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Ali Hatamizadeh

Self-attention is of vital importance in semantic segmentation as it enables modeling of long-range context, which translates into improved performance. We argue that it is equally important to model short-range context, especially to…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Hasib Zunair , A. Ben Hamza

We propose an approach to instance-level image segmentation that is built on top of category-level segmentation. Specifically, for each pixel in a semantic category mask, its corresponding instance bounding box is predicted using a deep…

Computer Vision and Pattern Recognition · Computer Science 2016-05-24 Zifeng Wu , Chunhua Shen , Anton van den Hengel

Purpose: Accurate segmentation of prostate cancer on magnetic resonance (MR) images is crucial for planning image-guided interventions such as targeted biopsies, cryoablation, and radiotherapy. However, subtle and variable tumour…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Junqing Yang , Natasha Thorley , Ahmed Nadeem Abbasi , Shonit Punwani , Zion Tse , Yipeng Hu , Shaheer U. Saeed

Modern histopathological image analysis relies on the segmentation of cell structures to derive quantitative metrics required in biomedical research and clinical diagnostics. State-of-the-art deep learning approaches predominantly apply…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 Yoav Alon , Huiyu Zhou

Whole-body PET/CT is a cornerstone of oncological imaging, yet accurate lesion segmentation remains challenging due to tracer heterogeneity, physiological uptake, and multi-center variability. While fully automated methods have advanced…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Maximilian Rokuss , Yannick Kirchhoff , Fabian Isensee , Klaus H. Maier-Hein

Melanoma is the most lethal form of skin cancer, with an increasing incidence rate worldwide. Analyzing histological images of melanoma by localizing and classifying tissues and cell nuclei is considered the gold standard method for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

We demonstrate our solution for the 2019 COCO panoptic segmentation task. Our method first performs instance segmentation and semantic segmentation separately, then combines the two to generate panoptic segmentation results. To enhance the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-21 Mehmet Yildirim , Yogesh Langhe

Nucleus segmentation and classification are the prerequisites in the workflow of digital pathology processing. However, it is very challenging due to its high-level heterogeneity and wide variations. This work proposes a deep neural network…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Sen Yang , Jinxi Xiang , Xiyue Wang

Self-supervised pretraining attempts to enhance model performance by obtaining effective features from unlabeled data, and has demonstrated its effectiveness in the field of histopathology images. Despite its success, few works concentrate…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Zhiyun Song , Penghui Du , Junpeng Yan , Kailu Li , Jianzhong Shou , Maode Lai , Yubo Fan , Yan Xu

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

The ability to dynamically extend a model to new data and classes is critical for multiple organ and tumor segmentation. However, due to privacy regulations, accessing previous data and annotations can be problematic in the medical domain.…

Image and Video Processing · Electrical Eng. & Systems 2023-07-24 Yixiao Zhang , Xinyi Li , Huimiao Chen , Alan Yuille , Yaoyao Liu , Zongwei Zhou

Interactive medical image segmentation refers to the accurate segmentation of the target of interest through interaction (e.g., click) between the user and the image. It has been widely studied in recent years as it is less dependent on…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Ao Chang , Xing Tao , Xin Yang , Yuhao Huang , Xinrui Zhou , Jiajun Zeng , Ruobing Huang , Dong Ni

In this work, we present SEEM, a promptable and interactive model for segmenting everything everywhere all at once in an image, as shown in Fig.1. In SEEM, we propose a novel decoding mechanism that enables diverse prompting for all types…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Xueyan Zou , Jianwei Yang , Hao Zhang , Feng Li , Linjie Li , Jianfeng Wang , Lijuan Wang , Jianfeng Gao , Yong Jae Lee

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee
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