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We present a novel neural network architecture, US-Net, for robust nuclei instance segmentation in histopathology images. The proposed framework integrates the nuclei detection and segmentation networks by sharing their outputs through the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-04 Zhaoyang Xu , Faranak Sobhani , Carlos Fernandez Moro , Qianni Zhang

This paper studies co-segmenting the common semantic object in a set of images. Existing works either rely on carefully engineered networks to mine the implicit semantic information in visual features or require extra data (i.e.,…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Xin Duan , Yan Yang , Liyuan Pan , Xiabi Liu

Instance segmentation of nuclei and glands in the histology images is an important step in computational pathology workflow for cancer diagnosis, treatment planning and survival analysis. With the advent of modern hardware, the recent…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Esha Sadia Nasir , Arshi Perviaz , Muhammad Moazam Fraz

Medical image segmentation assists in computer-aided diagnosis, surgeries, and treatment. Digitize tissue slide images are used to analyze and segment glands, nuclei, and other biomarkers which are further used in computer-aided medical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Saad Wazir , Muhammad Moazam Fraz

Tumor lesion segmentation on CT or MRI images plays a critical role in cancer diagnosis and treatment planning. Considering the inherent differences in tumor lesion segmentation data across various medical imaging modalities and equipment,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Hairong Shi , Songhao Han , Shaofei Huang , Yue Liao , Guanbin Li , Xiangxing Kong , Hua Zhu , Xiaomu Wang , Si Liu

This paper addresses text-supervised semantic segmentation, aiming to learn a model capable of segmenting arbitrary visual concepts within images by using only image-text pairs without dense annotations. Existing methods have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2024-04-08 Ji-Jia Wu , Andy Chia-Hao Chang , Chieh-Yu Chuang , Chun-Pei Chen , Yu-Lun Liu , Min-Hung Chen , Hou-Ning Hu , Yung-Yu Chuang , Yen-Yu Lin

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

Accurate semantic segmentation for histopathology image is crucial for quantitative tissue analysis and downstream clinical modeling. Recent segmentation foundation models have improved generalization through large-scale pretraining, yet…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Peixian Liang , Songhao Li , Shunsuke Koga , Yutong Li , Zahra Alipour , Yucheng Tang , Daguang Xu , Zhi Huang

The accurate segmentation of medical images is a crucial step in obtaining reliable morphological statistics. However, training a deep neural network for this task requires a large amount of labeled data to ensure high-accuracy results. To…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Xianjun Han , Qianqian Chen , Zhaoyang Xie , Xuejun Li , Hongyu Yang

Histopathology image segmentation is essential for delineating tissue structures in skin cancer diagnostics, but modeling spatial context and inter-tissue relationships remains a challenge, especially in regions with overlapping or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Shravan Venkatraman , Muthu Subash Kavitha , Joe Dhanith P R , V Manikandarajan , Jia Wu

Medical image segmentation plays a crucial role in computer-aided diagnosis. However, existing methods heavily rely on fully supervised training, which requires a large amount of labeled data with time-consuming pixel-wise annotations.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Yunqi Gu , Tao Zhou , Yizhe Zhang , Yi Zhou , Kelei He , Chen Gong , Huazhu Fu

In recent years, computational pathology has seen tremendous progress driven by deep learning methods in segmentation and classification tasks aiding prognostic and diagnostic settings. Nuclei segmentation, for instance, is an important…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Aman Shrivastava , P. Thomas Fletcher

Nuclei instance segmentation is critical in computational pathology for cancer diagnosis and prognosis. Recently, the Segment Anything Model has demonstrated exceptional performance in various segmentation tasks, leveraging its rich priors…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Jingze Su , Tianle Zhu , Jiaxin Cai , Zhiyi Wang , Qi Li , Xiao Zhang , Tong Tong , Shu Wang , Wenxi Liu

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

Segmentation of biomedical images is essential for studying and characterizing anatomical structures, detection and evaluation of pathological tissues. Segmentation has been further shown to enhance the reconstruction performance in many…

Medical Physics · Physics 2019-01-11 Subhamoy Mandal , Xosé Luís Deán-Ben , Daniel Razansky

Automated histopathological image analysis plays a vital role in computer-aided diagnosis of various diseases. Among developed algorithms, deep learning-based approaches have demonstrated excellent performance in multiple tasks, including…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Diana Mechtcheriakova , Amirreza Mahbod

Segmentation is a fundamental task in computer vision, with prompt-driven methods gaining prominence due to their flexibility. The Segment Anything Model (SAM) excels at point-prompted segmentation, while text-based models, often leveraging…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Suzhe Xu , Jialin Peng , Chengyuan Zhang

Due to low tissue contrast, irregular object appearance, and unpredictable location variation, segmenting the objects from different medical imaging modalities (e.g., CT, MR) is considered as an important yet challenging task. In this…

Computer Vision and Pattern Recognition · Computer Science 2018-05-10 Jinquan Sun , Yinghuan Shi , Yang Gao , Lei Wang , Luping Zhou , Wanqi Yang , Dinggang Shen

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Pre-trained on a large and diverse dataset, the segment anything model (SAM) is the first promptable foundation model in computer vision aiming at object segmentation tasks. In this work, we evaluate SAM for the task of nuclear instance…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Kesi Xu , Lea Goetz , Nasir Rajpoot