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Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 An Yan , Yu Wang , Yiwu Zhong , Zexue He , Petros Karypis , Zihan Wang , Chengyu Dong , Amilcare Gentili , Chun-Nan Hsu , Jingbo Shang , Julian McAuley

Understanding the physical world - governed by laws of motion, spatial relations, and causality - poses a fundamental challenge for multimodal large language models (MLLMs). While recent advances such as OpenAI o3 and GPT-4o demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Zhuobai Dong , Junchao Yi , Ziyuan Zheng , Haochen Han , Xiangxi Zheng , Alex Jinpeng Wang , Fangming Liu , Linjie Li

Vision-Language Models (VLM) can support clinicians by analyzing medical images and engaging in natural language interactions to assist in diagnostic and treatment tasks. However, VLMs often exhibit "hallucinogenic" behavior, generating…

Artificial Intelligence · Computer Science 2024-10-11 Shenghuan Sun , Alexander Schubert , Gregory M. Goldgof , Zhiqing Sun , Thomas Hartvigsen , Atul J. Butte , Ahmed Alaa

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Accurate semantic segmentation for histopathology image is crucial for quantitative tissue analysis and downstream clinical modeling. Recent segmentation foundation models have improved generalization through large-scale pretraining, yet…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Peixian Liang , Songhao Li , Shunsuke Koga , Yutong Li , Zahra Alipour , Yucheng Tang , Daguang Xu , Zhi Huang

Advancements in artificial intelligence have driven the development of numerous pathology foundation models capable of extracting clinically relevant information. However, there is currently limited literature independently evaluating these…

The deployment of vision-language models (VLMs) in dermatology is hindered by the trilemma of high computational costs, extreme data scarcity, and the black-box nature of deep learning. To address these challenges, we present SkinCLIP-VL, a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Zhixiang Lu , Shijie Xu , Kaicheng Yan , Xuyue Cai , Chong Zhang , Yulong Li , Angelos Stefanidis , Anh Nguyen , Jionglong Su

The field of computational pathology has witnessed remarkable progress in the development of both task-specific predictive models and task-agnostic self-supervised vision encoders. However, despite the explosive growth of generative…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Ming Y. Lu , Bowen Chen , Drew F. K. Williamson , Richard J. Chen , Kenji Ikamura , Georg Gerber , Ivy Liang , Long Phi Le , Tong Ding , Anil V Parwani , Faisal Mahmood

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Accurate diagnosis and prognosis assisted by pathology images are essential for cancer treatment selection and planning. Despite the recent trend of adopting deep-learning approaches for analyzing complex pathology images, they fall short…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Awais Naeem , Tianhao Li , Huang-Ru Liao , Jiawei Xu , Aby M. Mathew , Zehao Zhu , Zhen Tan , Ajay Kumar Jaiswal , Raffi A. Salibian , Ziniu Hu , Tianlong Chen , Ying Ding

Vision-Language Models (VLMs) have achieved remarkable progress across tasks such as visual question answering and image captioning. Yet, the extent to which these models perform visual reasoning as opposed to relying on linguistic priors…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Brigitta Malagurski Törtei , Yasser Dahou , Ngoc Dung Huynh , Wamiq Reyaz Para , Phúc H. Lê Khac , Ankit Singh , Sofian Chaybouti , Sanath Narayan

Existing vision-language understanding benchmarks largely consist of images of objects in their usual contexts. As a consequence, recent multimodal large language models can perform well with only a shallow visual understanding by relying…

Despite the remarkable progress of Vision-Language Models (VLMs) in adopting "Thinking-with-Images" capabilities, accurately evaluating the authenticity of their reasoning process remains a critical challenge. Existing benchmarks mainly…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Xuchen Li , Xuzhao Li , Renjie Pi , Shiyu Hu , Jian Zhao , Jiahui Gao

Liver cirrhosis is a major global health problem causing millions of deaths annually, and timely detection with aggressive treatment can significantly improve patients' quality of life. Modelling complex diseases from biomedical data is…

Other Quantitative Biology · Quantitative Biology 2026-04-29 Xueyuan Huang , Yuheng Wang , Yuanzhi He , Siqi Gou , Lu Bai , Wenqian Wu , Peifeng Liu , Aijia Wang , Tianhui Fan , Ze Zhou , Jiayu Xu

Spatial transcriptomics reveals gene expression patterns within tissue context, enabling precision oncology applications such as treatment response prediction, but its high cost and technical complexity limit clinical adoption. Predicting…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Won June Cho , Hongjun Yoon , Daeky Jeong , Hyeongyeol Lim , Yosep Chong

The automation of workflows in advanced microscopy is a key goal where foundation models like Language Models (LLMs) and Vision-Language Models (VLMs) show great potential. However, adapting these general-purpose models for specialized…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Robinson Umeike , Neil Getty , Yin Xiangyu , Yi Jiang

While Multimodal Large Language Models (MLLMs) exhibit strong performance on standard video tasks, their ability to faithfully summarize and reason over complex narratives remains poorly evaluated. Existing summarization benchmarks fragment…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Mengqi Shi , Haopeng Zhang

Transcriptomic assays such as the PAM50-based ROR-P score guide recurrence risk stratification in non-metastatic, ER-positive, HER2-negative breast cancer but are not universally accessible. Histopathology is routinely available and may…

The rapid advancements in large language models (LLMs) have unlocked their potential for multimodal tasks, where text and visual data are processed jointly. However, applying LLMs to medical imaging, particularly for chest X-rays (CXR),…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Nicholas Evans , Stephen Baker , Miles Reed

Automatic speech intelligibility assessment is crucial for monitoring speech disorders and therapy efficacy. However, existing methods are difficult to compare: research is fragmented across private datasets with inconsistent protocols. We…

Sound · Computer Science 2026-03-10 Bence Mark Halpern , Thomas Tienkamp , Defne Abur , Tomoki Toda