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Foundation models have emerged as a powerful paradigm in computational pathology (CPath), enabling scalable and generalizable analysis of histopathological images. While early developments centered on uni-modal models trained solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Xiaohui Chen , Yi He , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Multimodal large language models (MLLMs) have enabled a wide range of advanced vision-language applications, including fine-grained object recognition and contextual understanding. When querying specific regions or objects in an image,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Mingjie Xu , Jinpeng Chen , Yuzhi Zhao , Jason Chun Lok Li , Yue Qiu , Zekang Du , Mengyang Wu , Pingping Zhang , Kun Li , Hongzheng Yang , Wenao Ma , Jiaheng Wei , Qinbin Li , Kangcheng Liu , Wenqiang Lei

Puzzles have long served as compact and revealing probes of human cognition, isolating abstraction, rule discovery, and systematic reasoning with minimal reliance on prior knowledge. Leveraging these properties, visual puzzles have recently…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Maria Lymperaiou , Vasileios Karampinis , Giorgos Filandrianos , Angelos Vlachos , Chrysoula Zerva , Athanasios Voulodimos

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

Medical Visual Language Models have shown great potential in various healthcare applications, including medical image captioning and diagnostic assistance. However, most existing models rely on text-based instructions, limiting their…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Tan-Hanh Pham , Chris Ngo , Trong-Duong Bui , Minh Luu Quang , Tan-Huong Pham , Truong-Son Hy

Artificial intelligence (AI) holds strong potential for medical diagnostics, yet its clinical adoption is limited by a lack of interpretability and generalizability. This study introduces the Pathobiological Dictionary for Liver Cancer…

Large annotated datasets are essential for training robust Computer-Aided Diagnosis (CAD) models for breast cancer detection or risk prediction. However, acquiring such datasets with fine-detailed annotation is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

Recent advances in multimodal large language models (LLMs) have highlighted their potential for medical and surgical applications. However, existing surgical datasets predominantly adopt a Visual Question Answering (VQA) format with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Tae-Min Choi , Tae Kyeong Jeong , Garam Kim , Jaemin Lee , Yeongyoon Koh , In Cheul Choi , Jae-Ho Chung , Jong Woong Park , Juyoun Park

Recent advances in multimodal large language models enable new possibilities for image-based decision support. However, their reliability and operational trade-offs in neuroimaging remain insufficiently understood. We present a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Katarina Trojachanec Dineva , Stefan Andonov , Ilinka Ivanoska , Ivan Kitanovski , Sasho Gramatikov , Tamara Kostova , Monika Simjanoska Misheva , Kostadin Mishev

Despite the promise of computational pathology foundation models, adapting them to specific clinical tasks remains challenging due to the complexity of whole-slide image (WSI) processing, the opacity of learned features, and the wide range…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Abdul Rahman Diab , Emily E. Karn , Renchin Wu , Emily S. Ruiz , William Lotter

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Ultrasound is a widely-used imaging modality critical to global healthcare, yet its interpretation remains challenging due to its varying image quality on operators, noises, and anatomical structures. Although large vision-language models…

Vision-language models have demonstrated impressive capabilities in general medical visual question answering, yet due to limited interpretability, it remains unclear whether their predictions reflect evidence-grounded clinical reasoning or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Wen Ma , Fucheng Niu , Zhiting Fan , Zikai Xiao , Jiaxiang Liu , Zuozhu Liu

Existing medical reasoning benchmarks for vision-language models primarily focus on analyzing a patient's condition based on an image from a single visit. However, this setting deviates significantly from real-world clinical practice, where…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Junyi Zhang , Jia-Chen Gu , Wenbo Hu , Yu Zhou , Robinson Piramuthu , Nanyun Peng

As Vision-Language Models (VLMs) increasingly gain traction in medical applications, clinicians are progressively expecting AI systems not only to generate textual diagnoses but also to produce corresponding medical images that integrate…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Junjie Yang , Yuhao Yan , Gang Wu , Yuxuan Wang , Ruoyu Liang , Xinjie Jiang , Xiang Wan , Fenglei Fan , Yongquan Zhang , Feiwei Qin , Changmiao Wang

Recent advances in vision-language models have significantly expanded the frontiers of automated image analysis. However, applying these models in safety-critical contexts remains challenging due to the complex relationships between…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Muhammad Imran , Yugyung Lee

While multimodal large language models (MLLMs) exhibit strong performance on single-video tasks (e.g., video question answering), their capability for spatiotemporal pattern reasoning across multiple videos remains a critical gap in pattern…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Nannan Zhu , Yonghao Dong , Teng Wang , Xueqian Li , Shengjun Deng , Yijia Wang , Zheng Hong , Tiantian Geng , Guo Niu , Hanyan Huang , Xiongfei Yao , Shuaiwei Jiao

Self-supervised learning in vision-language processing exploits semantic alignment between imaging and text modalities. Prior work in biomedical VLP has mostly relied on the alignment of single image and report pairs even though clinical…

Vision Language Models (VLMs) have undergone a rapid evolution, giving rise to significant advancements in the realm of multimodal understanding tasks. However, the majority of these models are trained and evaluated on English-centric…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Yuichi Inoue , Kento Sasaki , Yuma Ochi , Kazuki Fujii , Kotaro Tanahashi , Yu Yamaguchi

Large Vision-Language Models (LVLMs) achieve strong performance on visual question answering benchmarks, yet often rely on spurious correlations rather than genuine causal reasoning. Existing evaluations primarily assess the correctness of…

Artificial Intelligence · Computer Science 2026-02-25 Dhita Putri Pratama , Soyeon Caren Han , Yihao Ding
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