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Clinicians may rely on medical coding systems such as International Classification of Diseases (ICD) to identify patients with diseases from Electronic Health Records (EHRs). However, due to the lack of detail and specificity as well as a…

Computation and Language · Computer Science 2022-05-19 Jingqing Zhang , Atri Sharma , Luis Bolanos , Tong Li , Ashwani Tanwar , Vibhor Gupta , Yike Guo

Clinical diagnosis, which aims to assign diagnosis codes for a patient based on the clinical note, plays an essential role in clinical decision-making. Considering that manual diagnosis could be error-prone and time-consuming, many…

Computation and Language · Computer Science 2021-01-28 Yichao Du , Pengfei Luo , Xudong Hong , Tong Xu , Zhe Zhang , Chao Ren , Yi Zheng , Enhong Chen

We present MOSAIC, a multi-agent Large Language Model (LLM) framework for solving challenging scientific coding tasks. Unlike general-purpose coding, scientific workflows require algorithms that are rigorous, interconnected with deep domain…

Computation and Language · Computer Science 2026-05-05 Siddeshwar Raghavan , Tanwi Mallick

International Classification of Diseases (ICD) coding is the task of assigning ICD diagnosis codes to clinical notes. This can be challenging given the large quantity of labels (nearly 9,000) and lengthy texts (up to 8,000 tokens). However,…

Computation and Language · Computer Science 2023-09-19 Junwen Duan , Han Jiang , Ying Yu

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

Computation and Language · Computer Science 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

ICD(International Classification of Diseases) coding involves assigning ICD codes to patients visit based on their medical notes. Considering ICD coding as a multi-label text classification task, researchers have developed sophisticated…

Computation and Language · Computer Science 2024-10-21 Bin Zhang , Junli Wang

Large scale veterinary clinical records can become a powerful resource for patient care and research. However, clinicians lack the time and resource to annotate patient records with standard medical diagnostic codes and most veterinary…

Computation and Language · Computer Science 2018-09-05 Allen Nie , Ashley Zehnder , Rodney L. Page , Arturo L. Pineda , Manuel A. Rivas , Carlos D. Bustamante , James Zou

Data science plays a critical role in biomedical research, but it requires professionals with expertise in coding and medical data analysis. Large language models (LLMs) have shown great potential in supporting medical tasks and performing…

Artificial Intelligence · Computer Science 2025-04-10 Zifeng Wang , Benjamin Danek , Ziwei Yang , Zheng Chen , Jimeng Sun

The work discusses the use of machine learning algorithms for anomaly detection in medical image analysis and how the performance of these algorithms depends on the number of annotators and the quality of labels. To address the issue of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Hieu H. Pham , Khiem H. Le , Tuan V. Tran , Ha Q. Nguyen

Health informatics research is characterized by diverse data modalities, rapid knowledge expansion, and the need to integrate insights across biomedical science, data analytics, and clinical practice. These characteristics make it…

Artificial Intelligence · Computer Science 2025-09-24 Yuxiao Cheng , Jinli Suo

The International Classification of Diseases (ICD) serves as a definitive medical classification system encompassing a wide range of diseases and conditions. The primary objective of ICD indexing is to allocate a subset of ICD codes to a…

Computation and Language · Computer Science 2024-05-30 Xindi Wang , Robert E. Mercer , Frank Rudzicz

Physician burnout in the United States has reached critical levels, driven in part by the administrative burden of Electronic Health Record (EHR) documentation and complex diagnostic codes. To relieve this strain and maintain strict patient…

Information Retrieval · Computer Science 2026-03-25 Peter Hartnett , Chung-Chi Huang , Sarah Hartnett , David Hartnett

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

As software systems evolve, developers increasingly work across multiple programming languages and often face the need to migrate code from one language to another. While automatic code translation offers a promising solution, it has long…

Software Engineering · Computer Science 2025-12-09 Fazle Rabbi , Soumit Kanti Saha , Tri Minh Triet Pham , Song Wang , Jinqiu Yang

Obtaining datasets labeled to facilitate model development is a challenge for most machine learning tasks. The difficulty is heightened for medical imaging, where data itself is limited in accessibility and labeling requires costly time and…

Computation and Language · Computer Science 2018-10-03 Nithya Attaluri , Ahmed Nasir , Carolynne Powe , Harold Racz , Ben Covington , Li Yao , Jordan Prosky , Eric Poblenz , Tobi Olatunji , Kevin Lyman

Manual assignment of Anatomical Therapeutic Chemical (ATC) codes to prescription records is a significant bottleneck in healthcare research and operations at Ontario Health and InterRAI Canada, requiring extensive expert time and effort. To…

Computation and Language · Computer Science 2024-12-11 Zijian Chen , John-Michael Gamble , Micaela Jantzi , John P. Hirdes , Jimmy Lin

Accurate medical symptom coding from unstructured clinical text, such as vaccine safety reports, is a critical task with applications in pharmacovigilance and safety monitoring. Symptom coding, as tailored in this study, involves…

Computation and Language · Computer Science 2025-04-07 Chengyang He , Wenlong Zhang , Violet Xinying Chen , Yue Ning , Ping Wang

The application of Large Language Models (LLMs) in healthcare is expanding rapidly, with one potential use case being the translation of formal medical reports into patient-legible equivalents. Currently, LLM outputs often need to be edited…

Multiagent Systems · Computer Science 2024-08-06 Malavikha Sudarshan , Sophie Shih , Estella Yee , Alina Yang , John Zou , Cathy Chen , Quan Zhou , Leon Chen , Chinmay Singhal , George Shih

Large language models (LLMs) have demonstrated notable potential in medical applications, yet they face substantial challenges in handling complex real-world clinical diagnoses using conventional prompting methods. Current prompt…

Artificial Intelligence · Computer Science 2026-03-02 Wenliang Li , Rui Yan , Xu Zhang , Li Chen , Hongji Zhu , Jing Zhao , Junjun Li , Mengru Li , Wei Cao , Zihang Jiang , Wei Wei , Kun Zhang , Shaohua Kevin Zhou