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For large language models (LLMs), post-training quantization (PTQ) can significantly reduce memory footprint and computational overhead. Model quantization is rapidly evolving. Though many papers report breakthrough results, they are often…

Machine Learning · Computer Science 2026-01-30 Yutong Liu , Cairong Zhao , Guosheng Hu

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

ML-powered code generation aims to assist developers to write code in a more productive manner, by intelligently generating code blocks based on natural language prompts. Recently, large pretrained deep learning models have substantially…

Large language models can be quantized to reduce inference time latency, model size, and energy consumption, thereby delivering a better user experience at lower cost. A challenge exists to deliver quantized models with minimal loss of…

Machine Learning · Computer Science 2025-07-24 Steven K. Esser , Jeffrey L. McKinstry , Deepika Bablani , Rathinakumar Appuswamy , Dharmendra S. Modha

The rapid scaling of language models (LMs) has resulted in unprecedented computational, memory, and energy requirements, making their training and deployment increasingly unsustainable. Quantization has emerged as an essential compression…

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

Computation and Language · Computer Science 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Multimodal Large Language Models (MLLMs) hold huge potential for usage in the medical domain, but their computational costs necessitate efficient compression techniques. This paper evaluates the impact of structural pruning and…

Artificial Intelligence · Computer Science 2025-09-25 Tanvir A. Khan , Aranya Saha , Ismam N. Swapnil , Mohammad A. Haque

Large Language Models offer impressive language capabilities but suffer from well-known limitations, including hallucinations, biases, privacy concerns, and high computational costs. These issues are largely driven by the combination of…

Computation and Language · Computer Science 2025-09-03 Jaime Collado-Montañez , L. Alfonso Ureña-López , Arturo Montejo-Ráez

Quantization is an effective technique for reducing the storage footprint and computational costs of Large Language Models (LLMs), but it often results in performance degradation. Existing post-training quantization methods typically use…

Computation and Language · Computer Science 2026-01-27 Everlyn Asiko Chimoto , Mostafa Elhoushi , Bruce A. Bassett

Quantization enables efficient deployment of large language models (LLMs) in resource-constrained environments by significantly reducing memory and computation costs. While quantized LLMs often maintain performance on perplexity and…

Artificial Intelligence · Computer Science 2025-08-28 Yao Fu , Xianxuan Long , Runchao Li , Haotian Yu , Mu Sheng , Xiaotian Han , Yu Yin , Pan Li

Large language models (LLMs) have become important tools in solving biological problems, offering improvements in accuracy and adaptability over conventional methods. Several benchmarks have been proposed to evaluate the performance of…

There is an increasing interest in developing artificial intelligence (AI) systems to process and interpret electronic health records (EHRs). Natural language processing (NLP) powered by pretrained language models is the key technology for…

Large Language Models (LLMs) have fundamentally altered how we approach scaling in machine learning. However, these models pose substantial computational and memory challenges, primarily due to the reliance on matrix multiplication (MatMul)…

The inference of Large language models (LLMs) requires immense computation and memory resources. To curtail these costs, quantisation has merged as a promising solution, but existing LLM quantisation mainly focuses on 8-bit. In this work,…

Machine Learning · Computer Science 2024-03-15 Cheng Zhang , Jianyi Cheng , Ilia Shumailov , George A. Constantinides , Yiren Zhao

Understanding context is key to understanding human language, an ability which Large Language Models (LLMs) have been increasingly seen to demonstrate to an impressive extent. However, though the evaluation of LLMs encompasses various…

Computation and Language · Computer Science 2024-02-02 Yilun Zhu , Joel Ruben Antony Moniz , Shruti Bhargava , Jiarui Lu , Dhivya Piraviperumal , Site Li , Yuan Zhang , Hong Yu , Bo-Hsiang Tseng

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Quantization is a practical technique for making large language models easier to deploy by reducing the precision used to store and operate on model weights. This can lower memory use and improve runtime feasibility on constrained hardware,…

Machine Learning · Computer Science 2026-01-22 Uygar Kurt

With the increasing application of large language models (LLMs) in the medical domain, evaluating these models' performance using benchmark datasets has become crucial. This paper presents a comprehensive survey of various benchmark…

While recent advancements in commercial large language models (LM) have shown promising results in medical tasks, their closed-source nature poses significant privacy and security concerns, hindering their widespread use in the medical…

Computation and Language · Computer Science 2024-07-02 Hyunjae Kim , Hyeon Hwang , Jiwoo Lee , Sihyeon Park , Dain Kim , Taewhoo Lee , Chanwoong Yoon , Jiwoong Sohn , Donghee Choi , Jaewoo Kang