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Related papers: Quantized Large Language Models in Biomedical Natu…

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Quantization is an essential and popular technique for improving the accessibility of large language models (LLMs) by reducing memory usage and computational costs while maintaining performance. In this study, we apply 4-bit Group Scaling…

Computation and Language · Computer Science 2025-08-18 Sahil Sk , Debasish Dhal , Sonal Khosla , Sk Shahid , Sambit Shekhar , Akash Dhaka , Shantipriya Parida , Dilip K. Prasad , Ondřej Bojar

Post-training quantization reduces the computational demand of Large Language Models (LLMs) but can weaken some of their capabilities. Since LLM abilities emerge with scale, smaller LLMs are more sensitive to quantization. In this paper, we…

Computation and Language · Computer Science 2024-08-02 Mert Yazan , Suzan Verberne , Frederik Situmeang

Post-training quantization (PTQ) has emerged as a promising technique to reduce the cost of large language models (LLMs). Specifically, PTQ can effectively mitigate memory consumption and reduce computational overhead in LLMs. To meet the…

Computation and Language · Computer Science 2024-06-07 Shiyao Li , Xuefei Ning , Luning Wang , Tengxuan Liu , Xiangsheng Shi , Shengen Yan , Guohao Dai , Huazhong Yang , Yu Wang

Large language models (LLMs) have wide applications in the field of natural language processing(NLP), such as GPT-4 and Llama. However, with the exponential growth of model parameter sizes, LLMs bring significant resource overheads. Low-bit…

Computation and Language · Computer Science 2025-02-27 Liangdong Liu , Zhitong Zheng , Cong Wang , Tianhuang Su , Zhenyu Yang

Large language models (LLMs) have grown beyond the memory capacity of single GPU devices, necessitating quantization techniques for practical deployment. While NF4 (4-bit NormalFloat) quantization enables 4$\times$ memory reduction,…

Machine Learning · Computer Science 2026-04-06 Xiangbo Qi , Chaoyi Jiang , Murali Annavaram

Large language models (LLMs) have been proven capable of memorizing their training data, which can be extracted through specifically designed prompts. As the scale of datasets continues to grow, privacy risks arising from memorization have…

Computation and Language · Computer Science 2023-11-07 Zhenhong Zhou , Jiuyang Xiang , Chaomeng Chen , Sen Su

The rise of large language models (LLMs) has significantly advanced various natural language processing (NLP) tasks. However, the resource demands of these models pose substantial challenges. Structured pruning is an effective approach to…

Machine Learning · Computer Science 2024-12-17 Changhai Zhou , Yuhua Zhou , Shijie Han , Qian Qiao , Hongguang Li

The use of generative AI-based coding assistants like ChatGPT and Github Copilot is a reality in contemporary software development. Many of these tools are provided as remote APIs. Using third-party APIs raises data privacy and security…

Software Engineering · Computer Science 2025-01-20 Negar Alizadeh , Boris Belchev , Nishant Saurabh , Patricia Kelbert , Fernando Castor

Recent advancements in reasoning language models have demonstrated remarkable performance in complex tasks, but their extended chain-of-thought reasoning process increases inference overhead. While quantization has been widely adopted to…

Computation and Language · Computer Science 2025-08-19 Ruikang Liu , Yuxuan Sun , Manyi Zhang , Haoli Bai , Xianzhi Yu , Tiezheng Yu , Chun Yuan , Lu Hou

Large language models (LLMs) are rapidly increasing in size, with the number of parameters becoming a key factor in the success of many commercial models, such as ChatGPT, Claude, and Bard. Even the recently released publicly accessible…

Computation and Language · Computer Science 2023-09-19 Somnath Roy

The capabilities of AI for biomedicine span a wide spectrum, from the atomic level, where it solves partial differential equations for quantum systems, to the molecular level, predicting chemical or protein structures, and further extending…

Computation and Language · Computer Science 2024-03-26 Zhenyu Bi , Sajib Acharjee Dip , Daniel Hajialigol , Sindhura Kommu , Hanwen Liu , Meng Lu , Xuan Wang

Large language models (LLMs) show best-in-class performance across a wide range of natural language processing applications. Training these models is an extremely computationally expensive task; frontier Artificial Intelligence (AI)…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-10 Alexander Interrante-Grant , Carla Varela-Rosa , Suhaas Narayan , Chris Connelly , Albert Reuther

Large language models have achieved significant advancements in complex mathematical reasoning benchmarks, such as MATH. However, their substantial computational requirements present challenges for practical deployment. Model quantization…

Computation and Language · Computer Science 2025-02-25 Zhen Li , Yupeng Su , Runming Yang , Congkai Xie , Zheng Wang , Zhongwei Xie , Ngai Wong , Hongxia Yang

Large language models (LLMs) exhibit excellent performance in various tasks. However, the memory requirements of LLMs present a great challenge when deploying on memory-limited devices, even for quantized LLMs. This paper introduces a…

Computation and Language · Computer Science 2025-02-24 Weilan Wang , Yu Mao , Dongdong Tang , Hongchao Du , Nan Guan , Chun Jason Xue

Quantization is widely used to accelerate inference and streamline the deployment of large language models (LLMs), yet its effects on self-explanations (SEs) remain unexplored. SEs, generated by LLMs to justify their own outputs, require…

Computation and Language · Computer Science 2026-01-05 Qianli Wang , Nils Feldhus , Pepa Atanasova , Fedor Splitt , Simon Ostermann , Sebastian Möller , Vera Schmitt

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

Computation and Language · Computer Science 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

This paper conducts a comprehensive investigation into applying large language models, particularly on BioBERT, in healthcare. It begins with thoroughly examining previous natural language processing (NLP) approaches in healthcare, shedding…

Artificial Intelligence · Computer Science 2023-10-13 Shyni Sharaf , V. S. Anoop

Data science plays a critical role in biomedical research, but it requires professionals with expertise in coding and medical data analysis. Large language models (LLMs) have shown great potential in supporting medical tasks and performing…

Artificial Intelligence · Computer Science 2025-04-10 Zifeng Wang , Benjamin Danek , Ziwei Yang , Zheng Chen , Jimeng Sun

Recent studies introduced effective compression techniques for Large Language Models (LLMs) via post-training quantization or low-bit weight representation. Although quantized weights offer storage efficiency and allow for faster inference,…

Computation and Language · Computer Science 2024-05-02 Irina Proskurina , Luc Brun , Guillaume Metzler , Julien Velcin