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Numerous medical systems powered by Large Language Models (LLMs) have achieved remarkable progress in diverse healthcare tasks. However, research on their medication safety remains limited due to the lack of real world datasets, constrained…

Artificial Intelligence · Computer Science 2025-11-07 Jiahao Zhao , Luxin Xu , Minghuan Tan , Lichao Zhang , Ahmadreza Argha , Hamid Alinejad-Rokny , Min Yang

We introduce a Bayesian prior distribution, the Logit-Normal continuous analogue of the spike-and-slab (LN-CASS), which enables flexible parameter estimation and variable/model selection in a variety of settings. We demonstrate its use and…

Applications · Statistics 2018-10-04 William Thomson , Sara Jabbari , Angela Taylor , Wiebke Arlt , David Smith

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Artificial Intelligence · Computer Science 2025-04-08 Zahra Atf , Seyed Amir Ahmad Safavi-Naini , Peter R. Lewis , Aref Mahjoubfar , Nariman Naderi , Thomas R. Savage , Ali Soroush

The rapid advancement of large language models (LLMs) in biological-medical applications has highlighted a gap between their potential and the limited scale and often low quality of available open-source annotated textual datasets. In…

Computation and Language · Computer Science 2025-12-19 Xunxin Cai , Chengrui Wang , Qingqing Long , Yuanchun Zhou , Meng Xiao

Large Language Models (LLMs) excel at understanding context and qualitative nuances but struggle with the rigorous and transparent reasoning required in high-stakes quantitative domains such as financial trading. We propose a model-first…

Computational Finance · Quantitative Finance 2025-12-02 Xiaoting Kuang , Boken Lin

Medical decision-support and advising systems are critical for emergency physicians to quickly and accurately assess patients' conditions and make diagnosis. Artificial Intelligence (AI) has emerged as a transformative force in healthcare…

Large language models (LLMs) are beginning to reshape how chemists plan and run reactions in organic synthesis. Trained on millions of reported transformations, these text-based models can propose synthetic routes, forecast reaction…

Artificial Intelligence · Computer Science 2025-08-08 Kartar Kumar Lohana Tharwani , Rajesh Kumar , Sumita , Numan Ahmed , Yong Tang

Empowered by vast internal knowledge reservoir, the new generation of large language models (LLMs) demonstrate untapped potential to tackle medical tasks. However, there is insufficient effort made towards summoning up a synergic effect…

Computation and Language · Computer Science 2025-05-23 Kexin Shang , Chia-Hsuan Chang , Christopher C. Yang

Clinical case reports encode temporal patient trajectories that are often underexploited by traditional machine learning methods relying on structured data. In this work, we introduce the forecasting problem from textual time series, where…

Computation and Language · Computer Science 2025-12-30 Shahriar Noroozizadeh , Sayantan Kumar , Jeremy C. Weiss

Causal discovery for both cross-sectional and temporal data has traditionally followed a dataset-specific paradigm, where a new model is fitted for each individual dataset. Such an approach limits the potential of multi-dataset pretraining.…

As large language models (LLMs) develop increasingly sophisticated capabilities and find applications in medical settings, it becomes important to assess their medical safety due to their far-reaching implications for personal and public…

Artificial Intelligence · Computer Science 2024-10-11 Tessa Han , Aounon Kumar , Chirag Agarwal , Himabindu Lakkaraju

This study examines the feasibility of applying large language models (LLMs) for forecasting the impact of traffic incidents on the traffic flow. The use of LLMs for this task has several advantages over existing machine learning-based…

Artificial Intelligence · Computer Science 2025-07-08 George Jagadeesh , Srikrishna Iyer , Michal Polanowski , Kai Xin Thia

Machine learning (ML) components are increasingly integrated into software products, yet their complexity and inherent uncertainty often lead to unintended and hazardous consequences, both for individuals and society at large. Despite these…

Software Engineering · Computer Science 2025-09-15 Yining Hong , Christopher S. Timperley , Christian Kästner

Due to the advantages of hypergraphs in modeling high-order relationships in complex systems, they have been applied to higher-order clustering, hypergraph neural networks and computer vision. These applications rely heavily on access to…

Social and Information Networks · Computer Science 2025-10-15 Bingqiao Gu , Jiale Zeng , Xingqin Qi , Dong Li

Fine-tuning large language models (LLMs) based on human preferences, commonly achieved through reinforcement learning from human feedback (RLHF), has been effective in improving their performance. However, maintaining LLM safety throughout…

Artificial Intelligence · Computer Science 2025-02-18 Yingshui Tan , Yilei Jiang , Yanshi Li , Jiaheng Liu , Xingyuan Bu , Wenbo Su , Xiangyu Yue , Xiaoyong Zhu , Bo Zheng

Recent advancements in large language models (LLMs) have significantly improved code generation and program comprehension, accelerating the evolution of software engineering. Current methods primarily enhance model performance by leveraging…

Computation and Language · Computer Science 2025-07-04 Weijie Lyu , Sheng-Jun Huang , Xuan Xia

Hidden Markov Models (HMMs) are foundational tools for modeling sequential data with latent Markovian structure, yet fitting them to real-world data remains computationally challenging. In this work, we show that pre-trained large language…

Machine Learning · Computer Science 2026-04-27 Yijia Dai , Zhaolin Gao , Yahya Sattar , Sarah Dean , Jennifer J. Sun

Modern epidemiological analytics increasingly use machine learning models that offer strong prediction but often lack calibrated uncertainty. Bayesian methods provide principled uncertainty quantification, yet are viewed as difficult to…

Machine Learning · Statistics 2025-11-18 Debashis Chatterjee

Advanced epidemic forecasting is critical for enabling precision containment strategies, highlighting its strategic importance for public health security. While recent advances in Large Language Models (LLMs) have demonstrated effectiveness…

Machine Learning · Computer Science 2025-05-20 Chenghua Gong , Rui Sun , Yuhao Zheng , Juyuan Zhang , Tianjun Gu , Liming Pan , Linyuan Lv

Large language models (LLMs) have revolutionized the field of AI, demonstrating unprecedented capacity across various tasks. However, the inference process for LLMs comes with significant computational costs. In this paper, we propose an…

Computation and Language · Computer Science 2023-05-30 Zangwei Zheng , Xiaozhe Ren , Fuzhao Xue , Yang Luo , Xin Jiang , Yang You