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Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Large language models (LLMs) have demonstrated unprecedented emergent capabilities, including content generation, translation, and simulation of human behavior. Field experiments, on the other hand, are widely employed in social studies to…

Computers and Society · Computer Science 2025-05-22 Yaoyu Chen , Yuheng Hu , Yingda Lu

Given the growing influence of language model-based agents on high-stakes societal decisions, from public policy to healthcare, ensuring their beneficial impact requires understanding the far-reaching implications of their suggestions. We…

Artificial Intelligence · Computer Science 2025-06-27 Chenkai Sun , Denghui Zhang , ChengXiang Zhai , Heng Ji

As the performance of large language models (LLMs) continues to advance, their adoption in the medical domain is increasing. However, most existing risk evaluations largely focused on general safety benchmarks. In the medical applications,…

Computation and Language · Computer Science 2026-01-12 Jean-Philippe Corbeil , Minseon Kim , Maxime Griot , Sheela Agarwal , Alessandro Sordoni , Francois Beaulieu , Paul Vozila

Pre-trained large language models (LLM) have emerged as a powerful tool for simulating various scenarios and generating output given specific instructions and multimodal input. In this work, we analyze the specific use of LLM to enhance a…

Machine Learning · Computer Science 2024-05-10 Yuhang Wu , Yingfei Wang , Chu Wang , Zeyu Zheng

Recent claims of strong performance by Large Language Models (LLMs) on causal discovery are undermined by a key flaw: many evaluations rely on benchmarks likely included in pretraining corpora. Thus, apparent success suggests that LLM-only…

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Large language models (LLMs) offer a valuable technology for various applications in healthcare. However, their tendency to hallucinate and the existing reliance on proprietary systems pose challenges in environments concerning critical…

Computation and Language · Computer Science 2025-02-27 Joshua Strong , Qianhui Men , Alison Noble

Large Language Models (LLMs) have revolutionized numerous domains, driving the rise of Language-Model-as-a-Service (LMaaS) platforms that process millions of queries daily. These platforms must minimize latency and meet Service Level…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-21 Zhihan Jiang , Yujie Huang , Guangba Yu , Junjie Huang , Jiazhen Gu , Michael R. Lyu

The medical ecosystem consists of the training of new clinicians and researchers, the practice of clinical medicine, and areas of adjacent research. There are many aspects of these domains that could benefit from the application of task…

Computers and Society · Computer Science 2025-07-29 Elisha D. O. Roberson

Clinical trials need to recruit a sufficient number of volunteer patients to demonstrate the statistical power of the treatment (e.g., a new drug) in curing a certain disease. Clinical trial recruitment has a significant impact on trial…

Machine Learning · Computer Science 2024-07-19 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

Efficient simulation is essential for enhancing proactive preparedness for sudden-onset disasters such as earthquakes. Recent advancements in large language models (LLMs) as world models show promise in simulating complex scenarios. This…

Computers and Society · Computer Science 2025-06-10 Lingyao Li , Dawei Li , Zhenhui Ou , Xiaoran Xu , Jingxiao Liu , Zihui Ma , Runlong Yu , Min Deng

Purpose: Machine learning is broadly used for clinical data analysis. Before training a model, a machine learning algorithm must be selected. Also, the values of one or more model parameters termed hyper-parameters must be set. Selecting…

Machine Learning · Computer Science 2018-12-10 Xueqiang Zeng , Gang Luo

Adding domain knowledge to a learning system is known to improve results. In multi-parameter Bayesian frameworks, such knowledge is incorporated as a prior. On the other hand, various model parameters can have different learning rates in…

Machine Learning · Computer Science 2022-06-22 Sareh Nabi , Houssam Nassif , Joseph Hong , Hamed Mamani , Guido Imbens

Large language models (LLMs) are increasingly applied in biomedical domains, yet their reliability in drug-safety prediction remains underexplored. In this work, we investigate whether LLMs incorporate socio-demographic information into…

Computation and Language · Computer Science 2025-10-17 Siying Liu , Shisheng Zhang , Indu Bala

A prior-informed large language model (LLM) driven multi-task learning framework is proposed for the unified description of multiple nuclear observables. By fine-tuning the pre-trained DeepSeek-R1-1.5B model with Low-Rank Adaptation (LoRA),…

Nuclear Theory · Physics 2026-05-29 S. J. Guo , S. Y. Wang , E. H. Wang , Z. M. Niu , Y. M. Ding

Psychological support hotlines provide critical support for individuals experiencing mental health emergencies, yet current assessments largely rely on human operators whose judgments may vary with professional experience and are…

Computation and Language · Computer Science 2026-05-12 Terumi Chiba , Yang Luo , Ziyun Cui , Yongsheng Tong , Chao Zhang

Recent advancements in large language models (LLMs) have accelerated progress toward artificial general intelligence, yet their potential to generate harmful content poses critical safety challenges. Existing alignment methods often…

Computation and Language · Computer Science 2025-10-08 Kehua Feng , Keyan Ding , Yuhao Wang , Menghan Li , Fanjunduo Wei , Xinda Wang , Qiang Zhang , Huajun Chen

Large language models (LLMs) encode rich semantic knowledge that can be useful for supervised learning, but their outputs are unreliable as statistical priors: they may be noisy, misspecified, or hallucinated. Existing LLM-informed learning…

Machine Learning · Statistics 2026-05-12 Erica Zhang , Naomi Sagan , Danny Tse , Fangzhao Zhang , Mert Pilanci , Jose Blanchet

Timely and accurate situational reports are essential for humanitarian decision-making, yet current workflows remain largely manual, resource intensive, and inconsistent. We present a fully automated framework that uses large language…

Computation and Language · Computer Science 2025-12-23 Ivan Decostanzi , Yelena Mejova , Kyriaki Kalimeri
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