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Uncertainty Quantification (UQ) is pivotal in enhancing the robustness, reliability, and interpretability of Machine Learning (ML) systems for healthcare, optimizing resources and improving patient care. Despite the emergence of ML-based…

Machine Learning · Computer Science 2025-05-07 L. Julián Lechuga López , Shaza Elsharief , Dhiyaa Al Jorf , Firas Darwish , Congbo Ma , Farah E. Shamout

Advances in architectural design, data availability, and compute have driven remarkable progress in semantic segmentation. Yet, these models often rely on relaxed Bayesian assumptions, omitting critical uncertainty information needed for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 M. M. A. Valiuddin , R. J. G. van Sloun , C. G. A. Viviers , P. H. N. de With , F. van der Sommen

Large language model-based agents are rapidly evolving from simple conversational assistants into autonomous systems capable of performing complex, professional-level tasks in various domains. While these advancements promise significant…

Modern machine learning methods including deep learning have achieved great success in predictive accuracy for supervised learning tasks, but may still fall short in giving useful estimates of their predictive {\em uncertainty}. Quantifying…

Large language models (LLMs) are increasingly employed in information-seeking and decision-making tasks. Despite their broad utility, LLMs tend to generate information that conflicts with real-world facts, and their persuasive style can…

Computation and Language · Computer Science 2024-09-19 Arslan Chaudhry , Sridhar Thiagarajan , Dilan Gorur

An increasing number of news and research articles report that AI adoption is allowing professionals to blur and extend the boundaries of their corporate roles. With the goal of understanding how work processes might be changing in an…

Artificial Intelligence · Computer Science 2026-05-22 Stephanie Rosenthal , Shamsi Iqbal

The widespread diffusion of Artificial Intelligence (AI)-based systems offers many opportunities to contribute to the well-being of individuals and the advancement of economies and societies. This diffusion is, however, closely accompanied…

Computers and Society · Computer Science 2024-10-18 L. H. Nguyen , S. Lins , M. Renner , A. Sunyaev

As AI systems become prevalent in high stakes domains such as surveillance and healthcare, researchers now examine how to design and implement them in a safe manner. However, the potential harms caused by systems to stakeholders in complex…

Artificial Intelligence · Computer Science 2019-11-21 Roel Dobbe , Thomas Krendl Gilbert , Yonatan Mintz

The diffusion of AI and big data is reshaping decision-making processes by increasing the amount of information that supports decisions while reducing direct interaction with data and empirical evidence. This paradigm shift introduces new…

Artificial Intelligence · Computer Science 2024-12-03 Mario Angelelli , Massimiliano Gervasi

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…

Machines are being increasingly used in decision-making processes, resulting in the realization that decisions need explanations. Unfortunately, an increasing number of these deployed models are of a 'black-box' nature where the reasoning…

Artificial Intelligence · Computer Science 2023-11-07 Sopam Dasgupta

The remarkable performance of large language models (LLMs) in content generation, coding, and common-sense reasoning has spurred widespread integration into many facets of society. However, integration of LLMs raises valid questions on…

Computation and Language · Computer Science 2025-07-03 Ola Shorinwa , Zhiting Mei , Justin Lidard , Allen Z. Ren , Anirudha Majumdar

Placing a human in the loop may abate the risks of deploying AI systems in safety-critical settings (e.g., a clinician working with a medical AI system). However, mitigating risks arising from human error and uncertainty within such…

The importance of uncertainty quantification is increasingly recognized in the diverse field of machine learning. Accurately assessing model prediction uncertainty can help provide deeper understanding and confidence for researchers and…

Machine Learning · Computer Science 2024-12-03 Tianyi Chen , Yingzhou Lu , Nan Hao , Yuanyuan Zhang , Capucine Van Rechem , Jintai Chen , Tianfan Fu

As large language models (LLMs) are increasingly used for factual question-answering, it becomes more important for LLMs to have the capability to communicate the likelihood that their answer is correct. For these verbalized expressions of…

Computation and Language · Computer Science 2025-12-15 Sophia Hager , David Mueller , Kevin Duh , Nicholas Andrews

The field of artificial intelligence (AI) is rapidly influencing health and healthcare, but bias and poor performance persists for populations who face widespread structural oppression. Previous work has clearly outlined the need for more…

Accurately quantifying uncertainty in large language models (LLMs) is crucial for their reliable deployment, especially in high-stakes applications. Current state-of-the-art methods for measuring semantic uncertainty in LLMs rely on strict…

Machine Learning · Computer Science 2024-10-31 Yashvir S. Grewal , Edwin V. Bonilla , Thang D. Bui

The development and deployment of artificial intelligence (AI) systems, with their profound societal impacts, raise critical challenges for governance. Historically, technological innovations have been governed by concentrated expertise…

Computers and Society · Computer Science 2025-02-14 Lucile Ter-Minassian

This review is designed to introduce mathematicians and computational scientists to quantum computing (QC) through the lens of uncertainty quantification (UQ) by presenting a mathematically rigorous and accessible narrative for…

Quantum Physics · Physics 2026-03-30 Ryan Bennink , Olena Burkovska , Konstantin Pieper , Jorge Ramirez , Elaine Wong

Despite the massive advancements in large language models (LLMs), they still suffer from producing plausible but incorrect responses. To improve the reliability of LLMs, recent research has focused on uncertainty quantification to predict…

Artificial Intelligence · Computer Science 2025-04-01 Yongjin Yang , Haneul Yoo , Hwaran Lee
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