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Artificial intelligence (AI) has revolutionized decision-making processes and systems throughout society and, in particular, has emerged as a significant technology in high-impact scenarios of national interest. Yet, despite AI's impressive…

Machine Learning · Statistics 2024-08-05 Gregory Canal , Vladimir Leung , Philip Sage , Eric Heim , I-Jeng Wang

Quantifying uncertainties for machine learning (ML) models is a foundational challenge in modern data analysis. This challenge is compounded by at least two key aspects of the field: (a) inconsistent terminology surrounding uncertainty and…

Machine Learning · Computer Science 2025-06-04 Shubhendu Trivedi , Brian D. Nord

In this paper, we describe an open source Python toolkit named Uncertainty Quantification 360 (UQ360) for the uncertainty quantification of AI models. The goal of this toolkit is twofold: first, to provide a broad range of capabilities to…

The adaptation and use of Machine Learning (ML) in our daily lives has led to concerns in lack of transparency, privacy, reliability, among others. As a result, we are seeing research in niche areas such as interpretability, causality, bias…

Machine Learning · Computer Science 2024-06-04 Fahimeh Fakour , Ali Mosleh , Ramin Ramezani

Artificial intelligence (AI) has huge potential to improve the health and well-being of people, but adoption in clinical practice is still limited. Lack of transparency is identified as one of the main barriers to implementation, as…

Artificial Intelligence · Computer Science 2021-01-06 Aniek F. Markus , Jan A. Kors , Peter R. Rijnbeek

The proliferation of open-source Large Language Models (LLMs) from various institutions has highlighted the urgent need for comprehensive evaluation methods. However, current evaluation platforms, such as the widely recognized HuggingFace…

Computation and Language · Computer Science 2024-11-01 Fanghua Ye , Mingming Yang , Jianhui Pang , Longyue Wang , Derek F. Wong , Emine Yilmaz , Shuming Shi , Zhaopeng Tu

This perspective paper examines a fundamental paradox in the relationship between professional expertise and artificial intelligence: as domain experts increasingly collaborate with AI systems by externalizing their implicit knowledge, they…

General Economics · Economics 2026-04-14 Venkat Ram Reddy Ganuthula , Krishna Kumar Balaraman

With the availability of large databases and recent improvements in deep learning methodology, the performance of AI systems is reaching or even exceeding the human level on an increasing number of complex tasks. Impressive examples of this…

Artificial Intelligence · Computer Science 2017-08-29 Wojciech Samek , Thomas Wiegand , Klaus-Robert Müller

Uncertainty is a key feature of any machine learning model and is particularly important in neural networks, which tend to be overconfident. This overconfidence is worrying under distribution shifts, where the model performance silently…

Machine Learning · Computer Science 2024-03-18 Arthur Thuy , Dries F. Benoit

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

A multitude of explainability methods and associated fidelity performance metrics have been proposed to help better understand how modern AI systems make decisions. However, much of the current work has remained theoretical -- without much…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Julien Colin , Thomas Fel , Remi Cadene , Thomas Serre

There is available an ever-increasing variety of procedures for managing uncertainty. These methods are discussed in the literature of artificial intelligence, as well as in the literature of philosophy of science. Heretofore these methods…

Artificial Intelligence · Computer Science 2013-01-30 Henry E. Kyburg , Choh Man Teng

Applications of large language models often involve the generation of free-form responses, in which case uncertainty quantification becomes challenging. This is due to the need to identify task-specific uncertainties (e.g., about the…

Computation and Language · Computer Science 2024-10-21 Ziyu Wang , Chris Holmes

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Uncertainty in machine learning refers to the degree of confidence or lack thereof in a model's predictions. While uncertainty quantification methods exist, explanations of uncertainty, especially in high-dimensional settings, remain an…

Machine Learning · Computer Science 2025-07-30 Isaac Roberts , Alexander Schulz , Sarah Schroeder , Fabian Hinder , Barbara Hammer

Precise estimation of predictive uncertainty in deep neural networks is a critical requirement for reliable decision-making in machine learning and statistical modeling, particularly in the context of medical AI. Conformal Prediction (CP)…

Machine Learning · Computer Science 2024-01-05 Hamed Karimi , Reza Samavi

The integration of artificial intelligence into business processes has significantly enhanced decision-making capabilities across various industries such as finance, healthcare, and retail. However, explaining the decisions made by these AI…

Artificial Intelligence · Computer Science 2024-10-29 Arne Grobrugge , Nidhi Mishra , Johannes Jakubik , Gerhard Satzger

The use of AI technologies is being integrated into the secure development of software-based systems, with an increasing trend of composing AI-based subsystems (with uncertain levels of performance) into automated pipelines. This presents a…

Software Engineering · Computer Science 2025-07-18 Emanuele Mezzi , Aurora Papotti , Fabio Massacci , Katja Tuma

For safety, medical AI systems undergo thorough evaluations before deployment, validating their predictions against a ground truth which is assumed to be fixed and certain. However, this ground truth is often curated in the form of…

Large language models (LLMs) have shown strong capabilities, enabling concise, context-aware answers in question answering (QA) tasks. The lack of transparency in complex LLMs has inspired extensive research aimed at developing methods to…

Computation and Language · Computer Science 2025-09-22 Yangyi Li , Mengdi Huai