Related papers: Single and Multi-Objective Performance Optimizatio…
Planning of biorefinery operations is complicated by the stochastic nature of physical and chemical characteristics of biomass feedstock, such as, moisture level and carbohydrate content. Biomass characteristics affect the performance of…
Constraint-based optimization of microbial strains and model-based bioprocess design have been used extensively to enhance yields in biotechnological processes. However, strain and process optimization are usually carried out in sequential…
Microalgae have been shown as a potential bioresource for food, biofuel, and pharmaceutical products. During the growth phases with corresponding environmental conditions, microalgae accumulate different amounts of various metabolites. We…
High-throughput experimental techniques and bioinformatics tools make it possible to obtain reconstructions of the metabolism of microbial species. Combined with mathematical frameworks such as flux balance analysis, which assumes that…
Modelling the evolution process for the growth of microalgae in an artificial pond is a huge challenge, given the complex interaction between hydrodynamics and biological processes occurring across various timescales. In this paper, we…
Dynamic flux balance analysis of a bioreactor is based on the coupling between a dynamic problem, which models the evolution of biomass, feeding substrates and metabolites, and a linear program, which encodes the metabolic activity inside…
The realization of efficient micro-machines built from active matter requires precise thermodynamic control far from equilibrium. Despite theoretical progress, the focus on single-parameter driving, coupled with strict theoretical…
The goal of this paper is to review and critically assess different methods to monitor key process variables for ethanol production from lignocellulosic biomass. Because cellulose-based biofuels cannot yet compete with non-cellulosic…
This work presents a mathematical model which describes both the genesis and growth of oxygenic photogranules (OPGs) and the related treatment process. The photogranule has been modelled as a free boundary domain with radial symmetry, which…
In precision aquaculture, the primary goal is to maximize biomass production while minimizing production costs. This objective can be achieved by optimizing factors that have a strong influence on fish growth, such as the feeding rate,…
A multiscale mathematical model describing the genesis and ecology of algal-bacterial photogranules and the metals biosorption on their solid matrix within a sequencing batch reactor (SBR) is presented. The granular biofilm is modelled as a…
Food production is a complex process which can benefit from many optimisation approaches. However, there is growing interest in methods that support customisation of food properties to satisfy individual consumer preferences. This paper…
We present experimental results demonstrating that, relative to continuous illumination, an increase of a factor of 3-10 in the photon efficiency of algal photo-synthesis is attainable via the judicious application of pulsed light for light…
MicroRNAs are small non-coding nucleotide sequences that regulate target protein expression at post-transcriptional levels. Biogenesis of microRNA is a highly regulated multi-step pathway. Regulation of miRNA biogenesis can be caused…
High-precision micromanipulation techniques, including optical tweezers and hydrodynamic trapping, have garnered wide-spread interest. Recent advances in optofluidic multiplexed assembly and microrobotics demonstrate significant progress,…
The flexible operation of electrified chemical processes, powered by renewable electricity, offers economic and ecological incentives, paving the way for a more sustainable chemical industry. However, this requires a departure from the…
Variations of physical and chemical characteristics of biomass reduce equipment utilization and increase operational costs of biomass processing. Biomass processing facilities use sensors to monitor the changes in biomass characteristics.…
The established microalgae growth models are semi-empirical or considerable fitting coefficients exist currently. Therefore, the ability of the model prediction is reduced by the numerous fitting coefficients. Furthermore, the predicted…
Renewable energy policies have driven the wood pellet market over the last decades worldwide. Among other factors, the return from this business depends largely on how well the producers manage the uncertainty associated with biomass yield…
Optogenetic modulation of adenosine triphosphatase (ATPase) expression represents a novel approach to maximize bioprocess efficiency by leveraging enforced adenosine triphosphate (ATP) turnover. In this study, we experimentally implement a…