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This report details our submission to the Mitotic Domain Generalization (MIDOG) 2025 challenge, which addresses the critical task of mitotic figure detection in histopathology for cancer prognostication. Following the "Bitter…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Zhuoyan Shen , Esther Bär , Maria Hawkins , Konstantin Bräutigam , Charles-Antoine Collins-Fekete

Counting of mitotic figures is a fundamental step in grading and prognostication of several cancers. However, manual mitosis counting is tedious and time-consuming. In addition, variation in the appearance of mitotic figures causes a high…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Mostafa Jahanifar , Adam Shephard , Neda Zamanitajeddin , Simon Graham , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Mitotic figure count is an important marker of tumor proliferation and has been shown to be associated with patients' prognosis. Deep learning based mitotic figure detection methods have been utilized to automatically locate the cell in…

Computer Vision and Pattern Recognition · Computer Science 2021-09-01 Jingtang Liang , Cheng Wang , Yujie Cheng , Zheng Wang , Fang Wang , Liyu Huang , Zhibin Yu , Yubo Wang

We propose a new training scheme for domain generalization in mitotic figure detection. Mitotic figures show different characteristics for each scanner. We consider each scanner as a 'domain' and the image distribution specified for each…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Youjin Chung , Jihoon Cho , Jinah Park

Detecting small unmanned aerial vehicles (UAVs) from a ground-to-air (G2A) perspective presents significant challenges, including extremely low pixel occupancy, cluttered aerial backgrounds, and strict real-time constraints. Existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Pengyu Chen , Haotian Sa , Yiwei Hu , Yuhan Cheng , Junbo Wang

Atypical mitotic figures (AMFs) are important histopathological markers yet remain challenging to identify consistently, particularly under domain shift stemming from scanner, stain, and acquisition differences. We present a simple…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Kaustubh Atey , Sameer Anand Jha , Gouranga Bala , Amit Sethi

Atypical mitotic figures are important biomarkers of tumor aggressiveness in histopathology, yet reliable recognition remains challenging due to severe class imbalance and variability across imaging domains. We present a DenseNet-121-based…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Adinath Dukre , Ankan Deria , Yutong Xie , Imran Razzak

Small object detection remains a challenging problem in the field of object detection. To address this challenge, we propose an enhanced YOLOv8-based model, SOD-YOLO. This model integrates an ASF mechanism in the neck to enhance multi-scale…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Peijun Wang , Jinhua Zhao

Addressing the spatial uncertainty and spectral blending challenges in CSST slitless spectroscopy, we present a deep learning-driven, end-to-end framework based on the You Only Look Once (YOLO) models. This approach directly detects,…

Instrumentation and Methods for Astrophysics · Physics 2025-10-29 Yingying Zhou , Chao Liu , Hao Tian , Xin Zhang , Nan Li

Atypical mitotic figures (AMFs) are rare abnormal cell divisions associated with tumor aggressiveness and poor prognosis. Their detection remains a significant challenge due to subtle morphological cues, class imbalance, and inter-observer…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Lavish Ramchandani , Gunjan Deotale , Dev Kumar Das

Road damage detection is a critical task for ensuring traffic safety and maintaining infrastructure integrity. While deep learning-based detection methods are now widely adopted, they still face two core challenges: first, the inadequate…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Zicheng Lin , Weichao Pan

The performance of deep learning models is known to scale with data quantity and diversity. In pathology, as in many other medical imaging domains, the availability of labeled images for a specific task is often limited. Self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jonas Ammeling , Jonathan Ganz , Emely Rosbach , Ludwig Lausser , Christof A. Bertram , Katharina Breininger , Marc Aubreville

Object detection is of paramount importance in biomedical image analysis, particularly for lesion identification. While current methodologies are proficient in identifying and pinpointing lesions, they often lack the precision needed to…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Zilin Chen , Shengnan Lu

Counting mitotic figures is time-intensive for pathologists and leads to inter-observer variability. Artificial intelligence (AI) promises a solution by automatically detecting mitotic figures while maintaining decision consistency.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Seungho Choe , Xiaoli Qin , Abubakr Shafique , Amanda Dy , Susan Done , Dimitrios Androutsos , April Khademi

Complete blood cell detection holds significant value in clinical diagnostics. Conventional manual microscopy methods suffer from time inefficiency and diagnostic inaccuracies. Existing automated detection approaches remain constrained by…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Guohua Wu , Shengqi Chen , Pengchao Deng , Wenting Yu

The density of mitotic figures within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of mitotic figures by pathologists is known to be subject to a strong…

Surface defect detection in industrial scenarios is both crucial and technically demanding due to the wide variability in defect types, irregular shapes and sizes, fine-grained requirements, and complex material textures. Although recent…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Jiawei Hu

Although advances in deep learning and aerial surveillance technology are improving wildlife conservation efforts, complex and erratic environmental conditions still pose a problem, requiring innovative solutions for cost-effective small…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Aditya Prashant Naidu , Hem Gosalia , Ishaan Gakhar , Shaurya Singh Rathore , Krish Didwania , Ujjwal Verma

The area of domain adaptation has been instrumental in addressing the domain shift problem encountered by many applications. This problem arises due to the difference between the distributions of source data used for training in comparison…

Computer Vision and Pattern Recognition · Computer Science 2023-04-12 Mazin Hnewa , Hayder Radha

This paper presents a comprehensive overview of the Ultralytics YOLO(You Only Look Once) family of object detectors, focusing the architectural evolution, benchmarking, deployment perspectives, and future challenges. The review begins with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ranjan Sapkota , Manoj Karkee