Related papers: Challenges and Lessons from MIDOG 2025: A Two-Stag…
Mitotic figure detection in histopathology images remains challenging due to significant domain shifts across different scanners, staining protocols, and tissue types. This paper presents our approach for the MIDOG 2025 challenge Track 1,…
Deep learning has driven significant advances in mitotic figure analysis within computational pathology. In this paper, we present our approach to the Mitosis Domain Generalization (MIDOG) 2025 Challenge, which consists of two distinct…
Automated detection and classification of mitotic figures especially distinguishing atypical from normal remain critical challenges in computational pathology. We present MitoDetect++, a unified deep learning pipeline designed for the MIDOG…
Mitotic figure (MF) detection in histopathology images is challenging due to large variations in slide scanners, staining protocols, tissue types, and the presence of artifacts. This paper presents a collection of training techniques - a…
Counting of mitotic figures is a fundamental step in grading and prognostication of several cancers. However, manual mitosis counting is tedious and time-consuming. In addition, variation in the appearance of mitotic figures causes a high…
We present a novel approach which extends the existing Fully Convolutional One-Stage Object Detector (FCOS) for mitotic figure detection. Our composite model adds a Feedback Attention Ladder CNN (FAL-CNN) model for classification of normal…
This report details our submission to the Mitotic Domain Generalization (MIDOG) 2025 challenge, which addresses the critical task of mitotic figure detection in histopathology for cancer prognostication. Following the "Bitter…
Mitotic figures represent a key histoprognostic feature in tumor pathology, providing crucial insights into tumor aggressiveness and proliferation. However, their identification remains challenging, subject to significant inter-observer…
Automated detection of mitotic figures in histopathology images is a challenging task: here, we present the different steps that describe the strategy we applied to participate in the MIDOG 2021 competition. The purpose of the competition…
Motivation: Accurate classification of mitotic figures into normal and atypical types is crucial for tumor prognostication in digital pathology. However, developing robust deep learning models for this task is challenging due to the subtle…
The detection of mitotic figures from different scanners/sites remains an important topic of research, owing to its potential in assisting clinicians with tumour grading. The MItosis DOmain Generalization (MIDOG) challenge aims to test the…
Counting mitotic figures is time-intensive for pathologists and leads to inter-observer variability. Artificial intelligence (AI) promises a solution by automatically detecting mitotic figures while maintaining decision consistency.…
The density of mitotic figures within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of mitotic figures by pathologists is known to be subject to a strong…
Domain variability is a common bottle neck in developing generalisable algorithms for various medical applications. Motivated by the observation that the domain variability of the medical images is to some extent compact, we propose to…
Mitotic figure count is an important marker of tumor proliferation and has been shown to be associated with patients' prognosis. Deep learning based mitotic figure detection methods have been utilized to automatically locate the cell in…
Accurate mitotic figure classification is crucial in computational pathology, as mitotic activity informs cancer grading and patient prognosis. Distinguishing atypical mitotic figures (AMFs), which indicate higher tumor aggressiveness, from…
Making histopathology image classifiers robust to a wide range of real-world variability is a challenging task. Here, we describe a candidate deep learning solution for the Mitosis Domain Generalization Challenge 2022 (MIDOG) to address the…
Recognition of mitotic figures in histologic tumor specimens is highly relevant to patient outcome assessment. This task is challenging for algorithms and human experts alike, with deterioration of algorithmic performance under shifts in…
Atypical mitotic figures are important biomarkers of tumor aggressiveness in histopathology, yet reliable recognition remains challenging due to severe class imbalance and variability across imaging domains. We present a DenseNet-121-based…
For the MIDOG mitosis detection challenge, we created a cascade algorithm consisting of a Mask-RCNN detector, followed by a classification ensemble consisting of ResNet50 and DenseNet201 to refine detected mitotic candidates. The MIDOG…