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Thermodynamic aspects of chemical reactions have a long history in the Physical Chemistry literature. In particular, biochemical cycles - the building-blocks of biochemical systems - require a source of energy to function. However, although…

Quantitative Methods · Quantitative Biology 2018-08-14 Peter J. Gawthrop , Edmund J. Crampin

Our Chemical e-Science Information Cloud (ChemCloud) - a Semantic Web based eScience infrastructure - integrates and automates a multitude of databases, tools and services in the domain of chemistry, pharmacy and bio-chemistry available at…

Databases · Computer Science 2010-12-09 Alexandru Todor , Adrian Paschke , Stephan Heineke

Recent advances in generative AI have accelerated the discovery of novel chemicals and materials. However, scaling these discoveries to industrial production remains a major bottleneck due to the synthesis gap -- the need to develop…

Machine Learning · Computer Science 2025-08-19 Sakhinana Sagar Srinivas , Shivam Gupta , Venkataramana Runkana

Handwritten archival tables contain rich historical information, yet transforming them into structured representations, such as Knowledge Graphs, requires integrating table structure recognition, handwriting recognition, and semantic…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Sarah Binta Alam Shoilee , Victor de Boer , Jacco van Ossenbruggen , Susan Legêne

In drug discovery, knowledge of the graph structure of chemical compounds is essential. Many thousands of scientific articles in chemistry and pharmaceutical sciences have investigated chemical compounds, but in cases the details of the…

Machine Learning · Statistics 2020-09-16 Martijn Oldenhof , Adam Arany , Yves Moreau , Jaak Simm

In this document, we discuss a multi-step approach to automated construction of a knowledge graph, for structuring and representing domain-specific knowledge from large document corpora. We apply our method to build the first knowledge…

Computation and Language · Computer Science 2026-05-15 Andrea Loreti , Kesi Chen , Ruby George , Robert Firth , Adriano Agnello , Shinnosuke Tanaka

A scientific paper can be divided into two major constructs which are Metadata and Full-body text. Metadata provides a brief overview of the paper while the Full-body text contains key-insights that can be valuable to fellow researchers. To…

Digital Libraries · Computer Science 2023-08-28 Azanzi Jiomekong , Sanju Tiwari

In recent years, the importance of well-documented metadata has been discussed increasingly in many research fields. Making all metadata generated during scientific research available in a findable, accessible, interoperable, and reusable…

Developing new molecular compounds is crucial to address pressing challenges, from health to environmental sustainability. However, exploring the molecular space to discover new molecules is difficult due to the vastness of the space. Here…

Machine Learning · Computer Science 2025-05-23 Manuel Ruiz-Botella , Marta Sales-Pardo , Roger Guimerà

Representing molecular structures effectively in chemistry remains a challenging task. Language models and graph-based models are extensively utilized within this domain, consistently achieving state-of-the-art results across an array of…

Machine Learning · Computer Science 2025-05-27 Nikolai Rekut , Alexey Orlov , Klea Ziu , Elizaveta Starykh , Martin Takac , Aleksandr Beznosikov

Networks provide a meaningful way to represent and analyze complex biological information, but the methodological details of network-based tools are often described for a technical audience. Graphery is a hands-on tutorial webserver…

Molecular Networks · Quantitative Biology 2024-02-19 Heyuan Zeng , Jinbiao Zhang , Gabriel A. Preising , Tobias Rubel , Pramesh Singh , Anna Ritz

Biomedical knowledge graphs (BKGs) have emerged as powerful tools for organizing and leveraging the vast and complex data found across the biomedical field. Yet, current reviews of BKGs often limit their scope to specific domains or…

Computation and Language · Computer Science 2025-01-23 Yuxing Lu , Sin Yee Goi , Xukai Zhao , Jinzhuo Wang

Metal-Organic Frameworks (MOFs) are a class of modular, porous crystalline materials that have great potential to revolutionize applications such as gas storage, molecular separations, chemical sensing, catalysis, and drug delivery. The…

The advent of simulation engines has revolutionized learning and operational efficiency for robots, offering cost-effective and swift pipelines. However, the lack of a universal simulation platform tailored for chemical scenarios impedes…

Robotics · Computer Science 2024-06-13 Shoujie Li , Yan Huang , Changqing Guo , Tong Wu , Jiawei Zhang , Linrui Zhang , Wenbo Ding

We study how to impose domain-consistent structure on large language models (LLMs) used for scientific reasoning and early-stage drug discovery. We present MedRule-KG, a compact knowledge-graph scaffold paired with a lightweight verifier…

Artificial Intelligence · Computer Science 2025-12-15 Crystal Su

The ability to reason beyond established knowledge allows Organic Chemists to solve synthetic problems and to invent novel transformations. Here, we propose a model which mimics chemical reasoning and formalises reaction prediction as…

Artificial Intelligence · Computer Science 2017-12-27 Marwin H. S. Segler , Mark P. Waller

Recently, the explosion of online education platforms makes a success in encouraging us to easily access online education resources. However, most of them ignore the integration of massive unstructured information, which inevitably brings…

Computation and Language · Computer Science 2022-05-10 Jianing Wang

Knowledge transfer among multiple networks using their outputs or intermediate activations have evolved through extensive manual design from a simple teacher-student approach (knowledge distillation) to a bidirectional cohort one (deep…

Computer Vision and Pattern Recognition · Computer Science 2019-12-18 Soma Minami , Tsubasa Hirakawa , Takayoshi Yamashita , Hironobu Fujiyoshi

There is enormous growth in various fields of research. This development is accompanied by new problems. To solve these problems efficiently and in an optimized manner, algorithms are created and described by researchers in the scientific…

Artificial Intelligence · Computer Science 2022-05-27 Jyotima Patel , Biswanath Dutta

The acceleration of materials discovery requires digital platforms that go beyond data repositories to embed learning, optimization, and decision-making directly into research workflows. We introduce DataScribe, an AI-native, cloud-based…

Machine Learning · Computer Science 2026-01-14 Divyanshu Singh , Doguhan Sarıtürk , Cameron Lea , Md Shafiqul Islam , Raymundo Arroyave , Vahid Attari
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