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Magnetic nanoparticles (MNPs) play an important role in biomedical applications including imaging modalities such as MRI and magnetic particle imaging (MPI). The latter one exploits the non-linear magnetization response of a large ensemble…

Mesoscale and Nanoscale Physics · Physics 2021-10-27 Hannes Albers , Tobias Knopp , Martin Möddel , Marija Boberg , Tobias Kluth

Magnetic particle imaging (MPI) is a non-invasive, non-ionizing imaging technique for the visualization and quantification of magnetic nanoparticles (MNPs). The technique is especially suitable for cell imaging as it offers zero background…

Magnetic particle imaging (MPI) is a relatively new imaging modality. The nonlinear magnetization behavior of nanoparticles in an applied magnetic field is employed to reconstruct an image of the concentration of nanoparticles. Finding a…

Applied Physics · Physics 2018-07-04 Tobias Kluth

Magnetic particle spectroscopy (MPS) is one of the most versatile methods to characterize the magnetic properties of magnetic nanoparticles (MNPs). The excitation magnetic field is one of the most crucial factors that affects the MPS signal…

Applied Physics · Physics 2023-04-25 Shaoqi Sun , Shijie Sun , Lijun Xu , Jing Zhong

Magnetic Particle Imaging (MPI) is a promising tracer-based, functional medical imaging technique which measures the non-linear magnetization response of magnetic nanoparticles to a dynamic magnetic field. For image reconstruction, system…

Image and Video Processing · Electrical Eng. & Systems 2021-08-26 Christina Brandt , Christiane Schmidt

Magnetic nanoparticles (MNPs) have been extensively used as contrasts and tracers for bioimaging, heating sources for tumor therapy, carriers for controlled drug delivery, and labels for magnetic immunoassays. Here, we describe a MNP…

Applied Physics · Physics 2019-09-11 Kai Wu , Jinming Liu , Diqing Su , Renata Saha , Jian-Ping Wang

Magnetic Particle Imaging (MPI) is a novel imaging modality with important applications such as angiography, stem cell tracking, and cancer imaging. Recently, there have been efforts to increase the functionality of MPI via multi-color…

Medical Physics · Physics 2017-05-23 Yavuz Muslu , Mustafa Utkur , Omer Burak Demirel , Emine Ulku Saritas

Magnetic Particle Imaging (MPI) is a tomographic imaging technique for determining the spatial distribution of superparamagnetic nanoparticles. Current MPI systems are capable of imaging iron masses over a wide dynamic range of more than…

We previously developed a system for projection-based magnetic particle imaging (MPI) with a field-free-line (FFL) encoding scheme. In the projection-based MPI, projection data are given by the convolution between the system function in the…

Medical Physics · Physics 2019-07-04 Kenya Murase

We develop a Bayesian nonparametric model for reconstructing magnetic resonance images (MRI) from highly undersampled k-space data. We perform dictionary learning as part of the image reconstruction process. To this end, we use the beta…

Computer Vision and Pattern Recognition · Computer Science 2015-06-15 Yue Huang , John Paisley , Qin Lin , Xinghao Ding , Xueyang Fu , Xiao-ping Zhang

Magnetic Particle Imaging (MPI) is an emerging imaging modality based on the magnetic response of superparamagnetic iron oxide nanoparticles to achieve high-resolution and real-time imaging without harmful radiation. One key challenge in…

Numerical Analysis · Mathematics 2025-01-13 Meira Iske , Hannes Albers , Tobias Knopp , Tobias Kluth

Magnetic Particle Imaging (MPI) is a promising tomographic technique for visualizing the spatio-temporal distribution of superparamagnetic nanoparticles, with applications ranging from cancer detection to real-time cardiovascular…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Magnetic Particle Imaging (MPI) is a promising noninvasive in vivo imaging modality that makes it possible to map the spatial distribution of superparamagnetic nanoparticles by exposing them to dynamic magnetic fields. In the Field-Free…

Numerical Analysis · Mathematics 2025-08-08 Vladyslav Gapyak , Thomas März , Andreas Weinmann

We report on our progress in the development of an atomic magnetometer (AM) based low-frequency magnetic particle imaging (MPI) scanner, expected to be free from Specific Absorption Rate (SAR) and Peripheral Nerve Stimulation (PNS)…

Instrumentation and Detectors · Physics 2017-01-16 Simone Colombo , Victor Lebedev , Alexey Tonyushkin , Zoran D. Grujic , Vladimir Dolgovskiy , Antoine Weis

Magnetic particle spectroscopy (MPS), also called magnetization response spectroscopy, is a novel measurement tool derived from magnetic particle imaging (MPI). It can be interpreted as a zero-dimensional version of MPI scanner. MPS was…

Applied Physics · Physics 2020-03-24 Kai Wu , Diqing Su , Renata Saha , Jinming Liu , Vinit Kumar Chugh , Jian-Ping Wang

The image reconstruction problem of the tomographic imaging technique magnetic particle imaging (MPI) requires the solution of a linear inverse problem. One prerequisite for this task is that the imaging operator that describes the mapping…

Computational Physics · Physics 2019-07-12 Tobias Kluth , Patryk Szwargulski , Tobias Knopp

We previously presented a lock-in-amplifier model for analyzing the behavior of signal harmonics in magnetic particle imaging (MPI). In that study, the magnetization and particle size distribution of magnetic nanoparticles (MNPs) were…

Medical Physics · Physics 2019-07-08 Kenya Murase

MR fingerprinting (MRF) is a rapid growing approach for fast quantitave MRI. A typical drawback of dictionary-based MRF is its explosion in size as a function of the number of reconstructed parameters, according to the curse of…

In this paper, the task-related fMRI problem is treated in its matrix factorization formulation, focused on the Dictionary Learning (DL) approach. The new method allows the incorporation of a priori knowledge associated both with the…

Machine Learning · Statistics 2019-08-20 Manuel Morante , Yannis Kopsinis , Sergios Theodoridis , Athanassios Protopapas

Magnetic Particle Imaging (MPI) has been shown to provide remarkable contrast for imaging applications such as angiography, stem cell tracking, and cancer imaging. Recently, there is growing interest in the functional imaging capabilities…

Medical Physics · Physics 2017-04-26 Mustafa Utkur , Yavuz Muslu , Emine Ulku Saritas
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