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Diffusion Probabilistic Models (DPMs) suffer from inefficient inference due to their slow sampling and high memory consumption, which limits their applicability to various medical imaging applications. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Yutong Sun , Sichen Zhu , Peng Qiu

Diffusion models achieved great success in image synthesis, but still face challenges in high-resolution generation. Through the lens of discrete cosine transformation, we find the main reason is that \emph{the same noise level on a higher…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Jiayan Teng , Wendi Zheng , Ming Ding , Wenyi Hong , Jianqiao Wangni , Zhuoyi Yang , Jie Tang

Ultrasound image reconstruction can be approximately cast as a linear inverse problem that has traditionally been solved with penalized optimization using the $l_1$ or $l_2$ norm, or wavelet-based terms. However, such regularization…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Yuxin Zhang , Clément Huneau , Jérôme Idier , Diana Mateus

Automatic magnetic resonance (MR) image processing pipelines are widely used to study people with multiple sclerosis (PwMS), encompassing tasks such as lesion segmentation and brain parcellation. However, the presence of lesion often…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Jinwei Zhang , Lianrui Zuo , Yihao Liu , Samuel Remedios , Bennett A. Landman , Jerry L. Prince , Aaron Carass

Pathology is the study of microscopic inspection of tissue, and a pathology diagnosis is often the medical gold standard to diagnose disease. Pathology images provide a unique challenge for computer-vision-based analysis: a single pathology…

Image denoising is the process of removing noise from noisy images, which is an image domain transferring task, i.e., from a single or several noise level domains to a photo-realistic domain. In this paper, we propose an effective image…

Image and Video Processing · Electrical Eng. & Systems 2019-06-05 Xianxu Hou , Hongming Luo , Jingxin Liu , Bolei Xu , Ke Sun , Yuanhao Gong , Bozhi Liu , Guoping Qiu

Pathology foundation models (PFMs) have recently emerged as powerful pretrained encoders for computational pathology, enabling transfer learning across a wide range of downstream tasks. However, systematic comparisons of these models for…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Fredrik K. Gustafsson , Constance Boissin , Johan Vallon-Christersson , David A. Clifton , Mattias Rantalainen

Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundation models in downstream tasks efficiently…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Dequan Wang , Xiaosong Wang , Lilong Wang , Mengzhang Li , Qian Da , Xiaoqiang Liu , Xiangyu Gao , Jun Shen , Junjun He , Tian Shen , Qi Duan , Jie Zhao , Kang Li , Yu Qiao , Shaoting Zhang

Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

Denoising diffusion models achieved impressive results on several image generation tasks often outperforming GAN based models. Recently, the generative capabilities of diffusion models have been employed for perceptual image compression,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Jonas Brenig , Radu Timofte

Batch effects arising from technical variations in histopathology staining protocols, scanners, and acquisition pipelines pose a persistent challenge for computational pathology, hindering cross-batch generalization and limiting reliable…

Machine Learning · Computer Science 2026-03-02 Xiaolong Zhang , Jianwei Zhang , Selim Sevim , Emek Demir , Ece Eksi , Xubo Song

Pathology Foundation Models (FMs) hold great promise for healthcare. Before they can be used in clinical practice, it is essential to ensure they are robust to variations between medical centers. We measure whether pathology FMs focus on…

Machine Learning · Computer Science 2025-02-04 Edwin D. de Jong , Eric Marcus , Jonas Teuwen

Visualizing the details of different cellular structures is of great importance to elucidate cellular functions. However, it is challenging to obtain high quality images of different structures directly due to complex cellular environments.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Yi Liu , Hao Yuan , Zhengyang Wang , Shuiwang Ji

Deep unfolding networks (DUNs) combine the interpretability of model-based methods with the learning ability of deep networks, yet remain limited for blind image restoration (BIR). Existing DUNs suffer from: (1) \textbf{Degradation-specific…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Chunming He , Rihan Zhang , Zheng Chen , Bowen Yang , Chengyu Fang , Yunlong Lin , Yulun Zhang , Fengyang Xiao , Sina Farsiu

Due to numerous hardware shortcomings, medical image acquisition devices are susceptible to producing low-quality (i.e., low contrast, inappropriate brightness, noisy, etc.) images. Regrettably, perceptually degraded images directly impact…

Image and Video Processing · Electrical Eng. & Systems 2025-03-12 S M A Sharif , Rizwan Ali Naqvi , Mithun Biswas , Woong-Kee Loh

Vision foundation models trained on discretely sampled images achieve strong performance on classification benchmarks, yet whether their representations encode the continuous processes underlying their training data remains unclear. This…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Pritika Vig , Ren-Chin Wu , William Lotter

In computational pathology, understanding and generation have evolved along disparate paths: advanced understanding models already exhibit diagnostic-level competence, whereas generative models largely simulate pixels. Progress remains…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Minghao Han , Yichen Liu , Yizhou Liu , Zizhi Chen , Jingqun Tang , Xuecheng Wu , Dingkang Yang , Lihua Zhang

Light field microscopy (LFM) has gained significant attention due to its ability to capture snapshot-based, large-scale 3D fluorescence images. However, existing LFM reconstruction algorithms are highly sensitive to sensor noise or require…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Jiayin Zhao , Zhenqi Fu , Tao Yu , Hui Qiao

Raw low light image enhancement (LLIE) has achieved much better performance than the sRGB domain enhancement methods due to the merits of raw data. However, the ambiguity between noisy to clean and raw to sRGB mappings may mislead the…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Qirui Yang , Qihua Cheng , Huanjing Yue , Le Zhang , Yihao Liu , Jingyu Yang
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