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This paper introduces a novel framework for image quality transfer based on conditional flow matching (CFM). Unlike conventional generative models that rely on iterative sampling or adversarial objectives, CFM learns a continuous flow…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Huu Tien Nguyen , Ahmed Karam Eldaly

Foundation models pretrained on large-scale datasets are revolutionizing the field of computational pathology (CPath). The generalization ability of foundation models is crucial for the success in various downstream clinical tasks. However,…

Low-light image enhancement (LLIE) techniques attempt to increase the visibility of images captured in low-light scenarios. However, as a result of enhancement, a variety of image degradations such as noise and color bias are revealed.…

Image and Video Processing · Electrical Eng. & Systems 2024-09-10 Savvas Panagiotou , Anna S. Bosman

Complex degradations like noise, blur, and low resolution are typical challenges in real world image fusion tasks, limiting the performance and practicality of existing methods. End to end neural network based approaches are generally…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Yu Shi , Yu Liu , Zhong-Cheng Wu , Juan Cheng , Huafeng Li , Xun Chen

Diffusion priors have been used for blind face restoration (BFR) by fine-tuning diffusion models (DMs) on restoration datasets to recover low-quality images. However, the naive application of DMs presents several key limitations. (i) The…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Senmao Li , Kai Wang , Joost van de Weijer , Fahad Shahbaz Khan , Chun-Le Guo , Shiqi Yang , Yaxing Wang , Jian Yang , Ming-Ming Cheng

Surgical segmentation is pivotal for scene understanding yet remains hindered by annotation scarcity and semantic inconsistency across diverse procedures. Existing approaches typically fine-tune natural foundation models (e.g., SAM) with…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Qing Xu , Kun Yuan , Yuxiang Luo , Yuhao Zhai , Wenting Duan , Nassir Navab , Zhen Chen

Foundation models have substantially advanced computational pathology by learning transferable visual representations from large histological datasets, yet their performance varies widely across tasks due to differences in training data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Wenhui Lei , Yusheng Tan , Anqi Li , Hanyu Chen , Hengrui Tian , Ruiying Li , Zhengqun Jiang , Fang Yan , Xiaofan Zhang , Shaoting Zhang

Multiplex imaging is revolutionizing pathology by enabling the simultaneous visualization of multiple biomarkers within tissue samples, providing molecular-level insights that traditional hematoxylin and eosin (H&E) staining cannot provide.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-06 Hyun-Jic Oh , Junsik Kim , Zhiyi Shi , Yichen Wu , Yu-An Chen , Peter K Sorger , Hanspeter Pfister , Won-Ki Jeong

Pathology foundation models (PFMs) have emerged as powerful pretrained encoders for computational pathology, but their robustness under clinically relevant distribution shifts remains insufficiently understood. We benchmark the robustness…

Image and Video Processing · Electrical Eng. & Systems 2026-04-29 Fredrik K. Gustafsson , Mattias Rantalainen

Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Pamela Osuna-Vargas , Maren H. Wehrheim , Lucas Zinz , Johanna Rahm , Ashwin Balakrishnan , Alexandra Kaminer , Mike Heilemann , Matthias Kaschube

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

The field of computational pathology has recently seen rapid advances driven by the development of modern vision foundation models (FMs), typically trained on vast collections of pathology images. Recent studies demonstrate that increasing…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Mikhail Karasikov , Joost van Doorn , Nicolas Känzig , Melis Erdal Cesur , Hugo Mark Horlings , Robert Berke , Fei Tang , Sebastian Otálora

In practice, digital pathology images are often affected by various factors, resulting in very large differences in color and brightness. Stain normalization can effectively reduce the differences in color and brightness of digital…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Hongtao Kang , Die Luo , Li Chen , Junbo Hu , Tingwei Quan , Shaoqun Zeng , Shenghua Cheng , Xiuli Liu

Unified image restoration is a significantly challenging task in low-level vision. Existing methods either make tailored designs for specific tasks, limiting their generalizability across various types of degradation, or rely on training…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Huaqiu Li , Yong Wang , Tongwen Huang , Hailang Huang , Haoqian Wang , Xiangxiang Chu

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jiawen Li , Jiali Hu , Xitong Ling , Yongqiang Lv , Yuxuan Chen , Yizhi Wang , Tian Guan , Yifei Liu , Yonghong He

Diffusion models excel at image restoration via probabilistic modeling of forward noise addition and reverse denoising, and their ability to handle complex noise while preserving fine details makes them well-suited for Low-Light Image…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Ying Liu , Junchao Zhang , Caiyun Wu

In histopathology, tissue sections are typically stained using common H&E staining or special stains (MAS, PAS, PASM, etc.) to clearly visualize specific tissue structures. The rapid advancement of deep learning offers an effective solution…

Image and Video Processing · Electrical Eng. & Systems 2025-04-23 Zizhi Chen , Xinyu Zhang , Minghao Han , Yizhou Liu , Ziyun Qian , Weifeng Zhang , Xukun Zhang , Jingwei Wei , Lihua Zhang

Low-light image enhancement remains a challenging problem due to severe noise, color distortion, contrast degradation, and loss of structural details under insufficient illumination. Existing methods typically apply uniform enhancement…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Bibhabasu Debnath , Sahana Ray , Sanjay Ghosh

Diffusion and flow-based generative models have shown strong potential for image restoration. However, image denoising under unknown and varying noise conditions remains challenging, because the learned vector fields may become inconsistent…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Jigang Duan , Genwei Ma , Xu Jiang , Wenfeng Xu , Ping Yang , Xing Zhao

Image degradation is a prevalent issue in various real-world applications, affecting visual quality and downstream processing tasks. In this study, we propose a novel framework that employs a Vision-Language Model (VLM) to automatically…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Jie Cai , Kangning Yang , Jiaming Ding , Lan Fu , Ling Ouyang , Jiang Li , Jinglin Shen , Zibo Meng
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