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Enhancing optical nonlinearities so that they become appreciable on the single photon level and lead to nonclassical light fields has been a central objective in quantum optics for many years. After this has been achieved in individual…

Quantum Physics · Physics 2016-09-20 Michael J. Hartmann

Stimulation of target neuronal populations using optogenetic techniques during specific sleep stages has begun to elucidate the mechanisms and effects of sleep. To conduct closed-loop optogenetic sleep studies in untethered animals, we…

Neurons and Cognition · Quantitative Biology 2021-08-30 Xilin Liu , Andrew G. Richardson

A recently introduced two-channel confocal microscope with correlated detection promises up to 50% improvement in transverse spatial resolution [Simon, Sergienko, Optics Express {\bf 18}, 9765 (2010)] via the use of photon correlations.…

Quantum Physics · Physics 2015-05-18 D. S. Simon , A. V. Sergienko

Artificial intelligence (AI) has emerged as a powerful tool to enhance decision-making and optimize treatment protocols in in vitro fertilization (IVF). In particular, AI shows significant promise in supporting decision-making during the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Jana Zakall , Birgit Pohn , Antonia Graf , Daniel Kovatchki , Arezoo Borji , Ragib Shahriar Islam , Hossam Haick , Heinz Strohmer , Sepideh Hatamikia

Multiphoton microscopy is widely used for live imaging. However, its acquisition speed remains limited by fluorophore emission rates and photodamage. To increase the pixel rate of a two-photon microscope beyond a few megahertz (MHz),…

We present a high-throughput optogenetic illumination system capable of simultaneous closed-loop light delivery to specified targets in populations of moving Caenorhabditis elegans. The instrument addresses three technical challenges: it…

Neurons and Cognition · Quantitative Biology 2022-02-01 Mochi Liu , Sandeep Kumar , Anuj K Sharma , Andrew M Leifer

Optical approaches to fluorescent, spectroscopic, and morphological imaging have made exceptional advances in the last decade. Super-resolution imaging and wide-field multiphoton imaging are now underpinning major advances across the…

Topological photonics enables robust light manipulation with third-order optical nonlinearity, yet integrating second-order optical nonlinearity into a topological system faces fundamental challenges: frequency-dependent topological…

Optics · Physics 2025-06-30 Ruoyu Wang , Yiming Pan , Xiaoqin Shen

The emerging field of optogenetics allows for optical activation or inhibition of neurons and other tissue in the nervous system. In 2005 optogenetic proteins were expressed in the nematode C. elegans for the first time. Since then, C.…

Neurons and Cognition · Quantitative Biology 2013-05-13 Steven J. Husson , Alexander Gottschalk , Andrew M. Leifer

Neural networks have enabled applications in artificial intelligence through machine learning, and neuromorphic computing. Software implementations of neural networks on conventional computers that have separate memory and processor (and…

We investigate two-photon quantum interference in an opaque scattering medium that intrinsically supports $10^6$ transmission channels. By adaptive spatial phase-modulation of the incident wavefronts, the photons are directed at targeted…

Recently, multi-modality scene perception tasks, e.g., image fusion and scene understanding, have attracted widespread attention for intelligent vision systems. However, early efforts always consider boosting a single task unilaterally and…

Computer Vision and Pattern Recognition · Computer Science 2023-05-12 Zhu Liu , Jinyuan Liu , Guanyao Wu , Long Ma , Xin Fan , Risheng Liu

Coherent control is extended to macroscopic processes under continuous pulsed laser irradiation. Here, this approach is used to analyze the experimentally measured two-photon phase control of currents emanating from a living brain cells…

Chemical Physics · Physics 2019-07-25 Cyrille Lavigne , Paul Brumer

Surface plasmons in graphene provide a compelling strategy for advanced photonic technologies thanks to their tight confinement, fast response and tunability. Recent advances in the field of all optical generation of graphene plasmons in…

Optics · Physics 2022-06-08 Y. Li , N. An , Z. Lu , Y. Wang , B. Chang , T. Tan , X. Guo , X. Xu , J. He , H. Xia , Z. Wu , Y. Su , Y. Liu , Y. Rao , G. Soavi , B. Yao

In contrast to recent studies [Rabl, Phys. Rev. Lett. 107, 063601 (2011); Nunnenkamp et al., Phys. Rev. Lett. 107, 063602 (2011)] on photon blockade that prevents subsequent photons from resonantly entering the cavity in optomechanical…

Quantum Physics · Physics 2013-04-22 Xun-Wei Xu , Yuan-Jie Li , Yu-xi Liu

Experiments show that spike-triggered stimulation performed with Bidirectional Brain-Computer-Interfaces (BBCI) can artificially strengthen connections between separate neural sites in motor cortex (MC). What are the neuronal mechanisms…

Neurons and Cognition · Quantitative Biology 2017-04-12 Guillaume Lajoie , Nedialko I. Krouchev , John F. Kalaska , Adrienne L. Fairhall , Eberhard E. Fetz

The capability of focus control has been central to optical technologies that require both high temporal and spatial resolutions. However, existing varifocal lens schemes are commonly limited to the response time on the microsecond…

We present a detailed theoretical analysis of a weakly driven multimode optomechanical system, in which two optical modes are strongly and near-resonantly coupled to a single mechanical mode via a three-wave mixing interaction. We calculate…

Quantum Physics · Physics 2013-04-12 P. Kómár , S. D. Bennett , K. Stannigel , S. J. M. Habraken , P. Rabl , P. Zoller , M. D. Lukin

Opto-mechanical oscillators that generate coherent acoustic waves are drawing much interest, in both fundamental research and applications. Narrowband oscillations can be obtained through the introduction of feedback to the acoustic wave.…

Optics · Physics 2018-11-16 H. Hagai Diamandi , Yosef London , Gil Bashan , Arik Bergman , Avi Zadok

Neuromorphic chip refers to an unconventional computing architecture that is modelled on biological brains. It is ideally suited for processing sensory data for intelligence computing, decision-making or context cognition. Despite rapid…

Emerging Technologies · Computer Science 2016-09-09 Shuchao Qin , Fengqiu Wang , Yujie Liu , Qing Wan , Xinran Wang , Yongbing Xu , Yi Shi , Xiaomu Wang , Rong Zhang
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