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Recent advances in computational pathology have led to the emergence of numerous foundation models. These models typically rely on general-purpose encoders with multi-instance learning for whole slide image (WSI) classification or apply…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Yuxuan Sun , Yixuan Si , Chenglu Zhu , Kai Zhang , Zhongyi Shui , Bowen Ding , Tao Lin , Lin Yang

Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mahesh Bhosale , Abdul Wasi , Yuanhao Zhai , Yunjie Tian , Samuel Border , Nan Xi , Pinaki Sarder , Junsong Yuan , David Doermann , Xuan Gong

Developing new methods for the automated analysis of clinical fetal and neonatal MRI data is limited by the scarcity of annotated pathological datasets and privacy concerns that often restrict data sharing, hindering the effectiveness of…

Cutaneous malignancies demand early detection for favorable outcomes, yet current diagnostics suffer from inter-observer variability and access disparities. While AI shows promise, existing dermatological systems are limited by homogeneous…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Sher Khan , Raz Muhammad , Adil Hussain , Muhammad Sajjad , Muhammad Rashid

Automated pathology image analysis is central to clinical diagnosis, but clinicians still ask which slide features drive a model's decision and why. Vision-language models can produce natural language explanations, but these are often…

Artificial Intelligence · Computer Science 2026-01-06 Kewen Cao , Jianxu Chen , Yongbing Zhang , Ye Zhang , Hongxiao Wang

The aggressiveness of prostate cancer, the most common cancer in men worldwide, is primarily assessed based on histopathological data using the Gleason scoring system. While artificial intelligence (AI) has shown promise in accurately…

Advancements in generative Artificial Intelligence (AI) hold great promise for automating radiology workflows, yet challenges in interpretability and reliability hinder clinical adoption. This paper presents an automated radiology report…

Learning medical visual representations from image-report pairs through joint learning has garnered increasing research attention due to its potential to alleviate the data scarcity problem in the medical domain. The primary challenges stem…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jun Wang , Lixing Zhu , Xiaohan Yu , Abhir Bhalerao , Yulan He

Artificial Intelligence (AI) brings advancements to support pathologists in navigating high-resolution tumor images to search for pathology patterns of interest. However, existing AI-assisted tools have not realized this promised potential…

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

Pathology has played a crucial role in the diagnosis and evaluation of patient tissue samples obtained from surgeries and biopsies for many years. The advent of Whole Slide Scanners and the development of deep learning technologies have…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Mieko Ochi , Daisuke Komura , Shumpei Ishikawa

Forensic pathology is critical in analyzing death manner and time from the microscopic aspect to assist in the establishment of reliable factual bases for criminal investigation. In practice, even the manual differentiation between…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Chen Shen , Jun Zhang , Xinggong Liang , Zeyi Hao , Kehan Li , Fan Wang , Zhenyuan Wang , Chunfeng Lian

As natural image understanding moves towards the pretrain-finetune era, research in pathology imaging is concurrently evolving. Despite the predominant focus on pretraining pathological foundation models, how to adapt foundation models to…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Jiaxuan Lu , Fang Yan , Xiaofan Zhang , Yue Gao , Shaoting Zhang

Current AI-assisted skin image diagnosis has achieved dermatologist-level performance in classifying skin cancer, driven by rapid advancements in deep learning architectures. However, unlike traditional vision tasks, skin images in general…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Xin Hu , Janet Wang , Jihun Hamm , Rie R Yotsu , Zhengming Ding

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

The development of AI-based methods to analyze radiology reports could lead to significant advances in medical diagnosis, from improving diagnostic accuracy to enhancing efficiency and reducing workload. However, the lack of…

Computation and Language · Computer Science 2025-08-14 Yuyan Ge , Kwan Ho Ryan Chan , Pablo Messina , René Vidal

Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools.…

Machine Learning · Computer Science 2025-10-07 Song Wang , Zhenyu Lei , Zhen Tan , Jundong Li , Javier Rasero , Aiying Zhang , Chirag Agarwal

This study proposes a novel approach combining Multimodal Deep Learning with intrinsic eXplainable Artificial Intelligence techniques to predict pathological response in non-small cell lung cancer patients undergoing neoadjuvant therapy.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Alice Natalina Caragliano , Claudia Tacconi , Carlo Greco , Lorenzo Nibid , Edy Ippolito , Michele Fiore , Giuseppe Perrone , Sara Ramella , Paolo Soda , Valerio Guarrasi

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

The clinical adoption of biomedical vision-language models is hindered by prompt optimization techniques that produce either uninterpretable latent vectors or single textual prompts. This lack of transparency and failure to capture the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Kaushitha Silva , Mansitha Eashwara , Sanduni Ubayasiri , Ruwan Tennakoon , Damayanthi Herath