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Related papers: PathMR: Multimodal Visual Reasoning for Interpreta…

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Large language models (LLMs) excel on general tasks yet still hallucinate in high-barrier domains such as pathology. Prior work often relies on domain fine-tuning, which neither expands the knowledge boundary nor enforces evidence-grounded…

Computation and Language · Computer Science 2025-10-13 Deshui Yu , Yizhi Wang , Saihui Jin , Taojie Zhu , Fanyi Zeng , Wen Qian , Zirui Huang , Jingli Ouyang , Jiameng Li , Zhen Song , Tian Guan , Yonghong He

Retrieving visual and textual information from medical literature and hospital records can enhance diagnostic accuracy for clinical image interpretation. However, multimodal retrieval-augmented diagnosis is highly challenging. We explore a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nir Mazor , Tom Hope

Large visual language models (VLMs) have shown strong multi-modal medical reasoning ability, but most operate as end-to-end black boxes, diverging from clinicians' evidence-based, staged workflows and hindering clinical accountability.…

Artificial Intelligence · Computer Science 2026-03-12 Yuexi Du , Jinglu Wang , Shujie Liu , Nicha C. Dvornek , Yan Lu

Explaining Deep Learning models is becoming increasingly important in the face of daily emerging multimodal models, particularly in safety-critical domains like medical imaging. However, the lack of detailed investigations into the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Anees Ur Rehman Hashmi , Dwarikanath Mahapatra , Mohammad Yaqub

Explaining the decision-making processes of Artificial Intelligence (AI) models is crucial for addressing their "black box" nature, particularly in tasks like image classification. Traditional eXplainable AI (XAI) methods typically rely on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Yifei Zhang , Tianxu Jiang , Bo Pan , Jingyu Wang , Guangji Bai , Liang Zhao

Pathological image segmentation faces numerous challenges, particularly due to ambiguous semantic boundaries and the high cost of pixel-level annotations. Although recent semi-supervised methods based on consistency regularization (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Mingxi Fu , Fanglei Fu , Xitong Ling , Huaitian Yuan , Tian Guan , Yonghong He , Lianghui Zhu

Reliable and interpretable decision-making is essential in medical imaging, where diagnostic outcomes directly influence patient care. Despite advances in deep learning, most medical AI systems operate as opaque black boxes, providing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Pirzada Suhail , Aditya Anand , Amit Sethi

Prevalent in biomedical applications (e.g., human phenotype research), multimodal datasets can provide valuable insights into the underlying physiological mechanisms. However, current machine learning (ML) models designed to analyze these…

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Yuzhe Lu , Adam Perer

Recent advances in agentic artificial intelligence, i.e. systems capable of autonomous perception, reasoning, and tool use, offer new opportunities for digital pathology. In this pilot study, we evaluate whether two agentic multimodal AI…

Human-Computer Interaction · Computer Science 2026-01-21 Marc Aubreville , Taryn A. Donovan , Christof A. Bertram

Vision language models (VLM) have achieved success in both natural language comprehension and image recognition tasks. However, their use in pathology report generation for whole slide images (WSIs) is still limited due to the huge size of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Jing Wei Tan , SeungKyu Kim , Eunsu Kim , Sung Hak Lee , Sangjeong Ahn , Won-Ki Jeong

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

Artificial intelligence (AI) holds strong potential for medical diagnostics, yet its clinical adoption is limited by a lack of interpretability and generalizability. This study introduces the Pathobiological Dictionary for Liver Cancer…

Recent advancements in deep neural networks have shown promise in aiding disease diagnosis and medical decision-making. However, ensuring transparent decision-making processes of AI models in compliance with regulations requires a…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Hyeon Bae Kim , Yong Hyun Ahn , Seong Tae Kim

Rare cancers comprise 20-25% of all malignancies but face major diagnostic challenges due to limited expert availability-especially in pediatric oncology, where they represent over 70% of cases. While pathology vision-language (VL)…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Dexuan He , Xiao Zhou , Wenbin Guan , Liyuan Zhang , Xiaoman Zhang , Sinuo Xu , Ge Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Yanfeng Wang , Kun Sun , Ya Zhang , Weidi Xie

Deep learning has driven significant advances in medical image analysis, yet its adoption in clinical practice remains constrained by the large size and lack of transparency in modern models. Advances in interpretability techniques such as…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Nikita Malik , Pratinav Seth , Neeraj Kumar Singh , Chintan Chitroda , Vinay Kumar Sankarapu

Deep learning has been increasingly incorporated into various computational pathology applications to improve its efficiency, accuracy, and robustness. Although successful, most previous approaches for image classification have crucial…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Anh Tien Nguyen , Jin Tae Kwak

Despite significant progress in pixel-level medical image analysis, existing medical image segmentation models rarely explore medical segmentation and diagnosis tasks jointly. However, it is crucial for patients that models can provide…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Lingran Song , Yucheng Zhou , Jianbing Shen

Deep neural networks have demonstrated superior performance in artificial intelligence applications, but the opaqueness of their inner working mechanism is one major drawback in their application. The prevailing unit-based interpretation is…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Lei Lyu , Chen Pang , Jihua Wang

Medical image segmentation is more clinically valuable when it supports diagnosis rather than merely producing lesion masks. However, diagnostically relevant lesion cues are often subtle and localized, while existing models may be…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Fengyi Zhang , Xujie Zeng , Mohan Liu , Zengyi Wang , Yalong Jiang
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