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Genome editing allows scientists to change an organism's DNA. One promising genome editing protocol, already validated in living organisms, is based on clustered regularly interspaced short palindromic repeats (CRISPR)/Cas protein-nucleic…

Biological Physics · Physics 2019-07-25 Angana Ray , Rosa Di Felice

Objective. This paper presents an overview of generalizable and explainable artificial intelligence (XAI) in deep learning (DL) for medical imaging, aimed at addressing the urgent need for transparency and explainability in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Ahmad Chaddad , Yan Hu , Yihang Wu , Binbin Wen , Reem Kateb

Predicting guide RNA (gRNA) activity is critical for effective CRISPR-Cas12 genome editing but remains challenging due to limited data, variation across protospacer adjacent motifs (PAMs-short sequence requirements for Cas binding), and…

Skin cancer is a serious worldwide health issue, precise and early detection is essential for better patient outcomes and effective treatment. In this research, we use modern deep learning methods and explainable artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Faysal Mahmud , Md. Mahin Mahfiz , Md. Zobayer Ibna Kabir , Yusha Abdullah

In recent years, deep learning has achieved unprecedented success in various computer vision tasks, particularly in object detection. However, the black-box nature and high complexity of deep neural networks pose significant challenges for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 FatemehSadat Seyedmomeni , Mohammad Ali Keyvanrad

This research examines the emerging technique of step-around prompt engineering in GenAI research, a method that deliberately bypasses AI safety measures to expose underlying biases and vulnerabilities in GenAI models. We discuss how…

Computers and Society · Computer Science 2026-01-23 Don Hickerson , Mike Perkins

Nowadays, deep neural networks are widely used in a variety of fields that have a direct impact on society. Although those models typically show outstanding performance, they have been used for a long time as black boxes. To address this,…

Machine Learning · Computer Science 2022-10-11 Huawei Sun , Lorenzo Servadei , Hao Feng , Michael Stephan , Robert Wille , Avik Santra

Recent development in the field of explainable artificial intelligence (XAI) has helped improve trust in Machine-Learning-as-a-Service (MLaaS) systems, in which an explanation is provided together with the model prediction in response to…

Machine Learning · Computer Science 2022-12-15 Truc Nguyen , Phung Lai , NhatHai Phan , My T. Thai

The effectiveness of Intrusion Detection Systems (IDS) is critical in an era where cyber threats are becoming increasingly complex. Machine learning (ML) and deep learning (DL) models provide an efficient and accurate solution for…

Cryptography and Security · Computer Science 2024-11-27 Kiymet Kaya , Elif Ak , Sumeyye Bas , Berk Canberk , Sule Gunduz Oguducu

Explainable Artificial Intelligence (XAI) has experienced a significant growth over the last few years. This is due to the widespread application of machine learning, particularly deep learning, that has led to the development of highly…

Artificial Intelligence · Computer Science 2020-10-13 Giulia Vilone , Luca Longo

Breast cancer (BC) stands as one of the most common malignancies affecting women worldwide, necessitating advancements in diagnostic methodologies for better clinical outcomes. This article provides a comprehensive exploration of the…

Artificial Intelligence · Computer Science 2025-12-11 Samita Bai , Sidra Nasir , Rizwan Ahmed Khan , Alexandre Meyer , Hubert Konik

A mutation in a protein-coding gene in DNA can alter the protein structure coded by the same gene. Structurally altered proteins usually lose their functions and sometimes gain an undesirable function instead. These types of mutations and…

Quantitative Methods · Quantitative Biology 2017-08-29 Kaan Aygen , Berkay Celik , Umut Eser

Given the sheer volume of surgical procedures and the significant rate of postoperative fatalities, assessing and managing surgical complications has become a critical public health concern. Existing artificial intelligence (AI) tools for…

MicroRNAs (miRNAs) are short sequences of ribonucleic acids that control the expression of target messenger RNAs (mRNAs) by binding them. Robust prediction of miRNA-mRNA pairs is of utmost importance in deciphering gene regulations but has…

Machine Learning · Computer Science 2016-09-27 Byunghan Lee , Junghwan Baek , Seunghyun Park , Sungroh Yoon

Being able to recognise defects in industrial objects is a key element of quality assurance in production lines. Our research focuses on visual anomaly detection in RGB images. Although Convolutional Neural Networks (CNNs) achieve high…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Daniel Gramelt , Timon Höfer , Ute Schmid

For strategic problems, intelligent systems based on Deep Reinforcement Learning (DRL) have demonstrated an impressive ability to learn advanced solutions that can go far beyond human capabilities, especially when dealing with complex…

Artificial Intelligence · Computer Science 2020-11-16 Jonas Andrulis , Ole Meyer , Grégory Schott , Samuel Weinbach , Volker Gruhn

Explainable Artificial Intelligence (XAI) has emerged as a critical tool for interpreting the predictions of complex deep learning models. While XAI has been increasingly applied in various domains within acoustics, its use in bioacoustics,…

Sound · Computer Science 2025-09-11 Zubair Faruqui , Mackenzie S. McIntire , Rahul Dubey , Jay McEntee

The rapid advancement of Generative Artificial Intelligence (GenAI) has introduced new opportunities for transforming higher education, particularly in fields that require analytical reasoning and regulatory compliance, such as…

Computers and Society · Computer Science 2025-02-24 Mahmoud Elkhodr , Ergun Gide

Artificial neural network (ANN) ability to learn, correct errors, and transform a large amount of raw data into useful medical decisions for treatment and care have increased its popularity for enhanced patient safety and quality of care.…

Machine Learning · Computer Science 2021-12-08 Muhammad Azeem , Shumaila Javaid , Hamza Fahim , Nasir Saeed

Artificial intelligence (AI)-native radio access networks (RANs) will serve vertical industries with stringent requirements: smart grids, autonomous vehicles, remote healthcare, industrial automation, etc. To achieve these requirements,…

Networking and Internet Architecture · Computer Science 2025-11-25 Osman Tugay Basaran , Falko Dressler