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Cybersecurity vendors consistently apply AI (Artificial Intelligence) to their solutions and many cybersecurity domains can benefit from AI technology. However, black-box AI techniques present some difficulties in comprehension and adoption…

Cryptography and Security · Computer Science 2023-03-03 Carlos Mendes , Tatiane Nogueira Rios

Remarkable success of modern image-based AI methods and the resulting interest in their applications in critical decision-making processes has led to a surge in efforts to make such intelligent systems transparent and explainable. The need…

Artificial Intelligence · Computer Science 2020-11-30 Adriano Lucieri , Muhammad Naseer Bajwa , Andreas Dengel , Sheraz Ahmed

Deep learning has become popular because of its potential to achieve high accuracy in prediction tasks. However, accuracy is not always the only goal of statistical modelling, especially for models developed as part of scientific research.…

Machine Learning · Computer Science 2021-10-19 Thomas P Quinn , Sunil Gupta , Svetha Venkatesh , Vuong Le

What does it mean for a generative AI model to be explainable? The emergent discipline of explainable AI (XAI) has made great strides in helping people understand discriminative models. Less attention has been paid to generative models that…

Human-Computer Interaction · Computer Science 2022-02-11 Jiao Sun , Q. Vera Liao , Michael Muller , Mayank Agarwal , Stephanie Houde , Kartik Talamadupula , Justin D. Weisz

Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

The implementation of Artificial Intelligence (AI) systems in the manufacturing domain enables higher production efficiency, outstanding performance, and safer operations, leveraging powerful tools such as deep learning and reinforcement…

Artificial Intelligence · Computer Science 2021-07-07 Georgios Sofianidis , Jože M. Rožanec , Dunja Mladenić , Dimosthenis Kyriazis

This study explores the integration of multiple Explainable AI (XAI) techniques to enhance the interpretability of deep learning models for brain tumour detection. A custom Convolutional Neural Network (CNN) was developed and trained on the…

Artificial Intelligence · Computer Science 2026-02-06 Patrick McGonagle , William Farrelly , Kevin Curran

There has recently been a surge of work in explanatory artificial intelligence (XAI). This research area tackles the important problem that complex machines and algorithms often cannot provide insights into their behavior and thought…

Artificial Intelligence · Computer Science 2019-02-05 Leilani H. Gilpin , David Bau , Ben Z. Yuan , Ayesha Bajwa , Michael Specter , Lalana Kagal

Artificial Intelligence (AI) technology is based on theory and development of computer systems able to perform tasks that normally require human intelligence. In this context, deep learning is a family of computational methods that allow an…

Computers and Society · Computer Science 2019-05-17 Mario Coccia

Machine learning technologies for protein function prediction are black box models. Despite their potential to identify key drug targets with high accuracy and accelerate therapy development, the adoption of these methods depends on…

Biomolecules · Quantitative Biology 2025-12-02 Ananya Krishna , Valentina Simon , Arjan Kohli

Artificial intelligence (AI) models are increasingly finding applications in the field of medicine. Concerns have been raised about the explainability of the decisions that are made by these AI models. In this article, we give a systematic…

Machine Learning · Computer Science 2023-04-12 Subrato Bharati , M. Rubaiyat Hossain Mondal , Prajoy Podder

Nowadays, deep neural networks are widely used in mission critical systems such as healthcare, self-driving vehicles, and military which have direct impact on human lives. However, the black-box nature of deep neural networks challenges its…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Arun Das , Paul Rad

Generative artificial intelligence (GenAI) has become a transformative approach in bioinformatics that often enables advancements in genomics, proteomics, transcriptomics, structural biology, and drug discovery. To systematically identify…

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

While deep learning models have demonstrated remarkable success in numerous domains, their black-box nature remains a significant limitation, especially in critical fields such as medical image analysis and inference. Existing…

Machine Learning · Computer Science 2025-05-13 David Zucker

While artificial intelligence (AI) has become widespread, many commercial AI systems are not yet accessible to individual researchers nor the general public due to the deep knowledge of the systems required to use them. We believe that AI…

Multiplex and multi-directional control of metabolic pathways is crucial for metabolic engineering to improve product yield of fuels, chemicals, and pharmaceuticals. To achieve this goal, artificial transcriptional regulators such as…

Biomolecules · Quantitative Biology 2017-04-12 Jiayuan Sheng , Weihua Guo , Christine Ash , Brendan Freitas , Mitchell Paoletti , Xueyang Feng

CRISPR systems experience off-target effects that interfere with the ability to accurately perform genetic edits. While empirical models predict off-target effects in specific platforms, there is a gap for a wide-ranging mechanistic model…

Biomolecules · Quantitative Biology 2021-09-30 Aset Khakimzhan , David Garenne , Benjamin I. Tickman , Jason Fontana , James Carothers , Vincent Noireaux

With the availability of large datasets and ever-increasing computing power, there has been a growing use of data-driven artificial intelligence systems, which have shown their potential for successful application in diverse areas. However,…

Cryptography and Security · Computer Science 2021-08-05 Jose N. Paredes , Juan Carlos L. Teze , Gerardo I. Simari , Maria Vanina Martinez

Autonomous driving has achieved significant milestones in research and development over the last two decades. There is increasing interest in the field as the deployment of autonomous vehicles (AVs) promises safer and more ecologically…

Artificial Intelligence · Computer Science 2024-04-29 Shahin Atakishiyev , Mohammad Salameh , Hengshuai Yao , Randy Goebel