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Mid-infrared spectroscopy offers powerful label-free molecular analysis capabilities but faces significant challenges when analyzing complex biological samples. Here, we present a transformative surface-enhanced infrared absorption…

Mid-infrared hyperspectral imaging has become an indispensable tool to spatially resolve chemical information in a wide variety of samples. However, acquiring three-dimensional data cubes is typically time-consuming due to the limited speed…

Optics · Physics 2026-05-29 Jianan Fang , Kun Huang , Ruiyang Qin , Yan Liang , E Wu , Ming Yan , Heping Zeng

Hyperspectral imaging provides high-dimensional spatial-temporal-spectral information revealing intrinsic matter characteristics. Here we report an on-chip computational hyperspectral imaging framework with high spatial and temporal…

Chemical imaging based on mid-infrared (MIR) spectroscopic contrast is an important technique with a myriad of applications, including biomedical imaging and environmental monitoring. Current MIR cameras, however, lack in performance and…

Instrumentation and Detectors · Physics 2021-07-06 David Knez , Adam M. Hanninen , Richard C. Prince , Eric O. Potma , Dmitry A. Fishman

Mid-infrared (MIR) spectrometers are invaluable tools for molecular fingerprinting and hyper-spectral imaging. Among the available spectroscopic approaches, GHz MIR dual-comb absorption spectrometers have the potential to simultaneously…

Millimetre-wave observations represent an important tool for Cosmology studies. The Line Intensity Mapping (LIM) technique has been proposed to map in three dimensions the specific intensity due to line (e.g. [CII], CO) emission, for…

Instrumentation and Methods for Astrophysics · Physics 2023-08-29 Usasi Chowdhury , Florence Levy-Bertrand , Martino Calvo , Johannes Goupy , Alessandro Monfardini

The emerging technique of mid-infrared optical coherence tomography (MIR-OCT) takes advantage of the reduced scattering of MIR light in various materials and devices, enabling tomographic imaging at deeper penetration depths. Because of…

Absorption spectroscopy is a fundamental tool for probing molecular structure. However, performing absorption spectroscopy on individual molecules is challenging due to the low signal-to-noise ratio. Here, we report on a nondestructive…

Sensitive mid-infrared (MIR) detection is highly demanded in various applications, ranging from remote sensing, infrared surveillance, environmental monitoring to industrial inspection. Among others, upconversion infrared detectors have…

Optics · Physics 2026-05-29 Xiaohan Liu , Kun Huang , Wen Zhang , Ben Sun , Jianan Fang , Yan Liang , Heping Zeng

Upconversion imaging, where mid infrared (IR) photons are converted to visible and near IR photons via a nonlinear crystal and detected on cheap and high-performance Silicon detectors, is an appealing method to address the limitations of…

Optics · Physics 2020-02-05 Michael Mrejen , Yoni Erlich , Assaf Levanon , Haim Suchowski

Minfrared spectroscopic imaging (MIRSI) is an emerging class of label-free, biochemically quantitative technologies targeting digital histopathology. Conventional histopathology relies on chemical stains that alter tissue color. This…

Image and Video Processing · Electrical Eng. & Systems 2022-07-26 Mahsa Lotfollahi , Nguyen Tran , Sebastian Berisha , Chalapathi Gajjela , Zhu Han , David Mayerich , Rohith Reddy

Mid-infrared spectroscopy probes molecular vibrations to identify chemical species and functional groups. Therefore, mid-infrared hyperspectral imaging is one of the most powerful and promising candidates for chemical imaging using optical…

Optics · Physics 2023-07-06 Yue Zhao , Shota Kusama , Yuji Furutani , Wei-Hong Huang , Chih-Wei Luo , Takao Fuji

The mid-infrared (MIR) spectral range, pertaining to important applications such as molecular 'fingerprint' imaging, remote sensing, free space telecommunication and optical radar, is of particular scientific interest and technological…

Multispectral imaging (MSI) captures data across multiple spectral bands, offering enhanced informational depth compared to standard RGB imaging and benefiting diverse fields such as agriculture, medical diagnostics, and industrial…

Instrumentation and Detectors · Physics 2025-08-29 Muchen Zhu , Baolei Liu , Yao Wang , Linjun Zhai , Jiaqi Song , Nana Liu , Zhaohua Yang , Lei Ding , Fan Wang

Waveguide-integrated mid-infrared (MIR) photodetectors are pivotal components for the development of molecular spectroscopy applications, leveraging mature photonic integrated circuit (PIC) technologies. Despite various strategies, critical…

Expanding far beyond traditional applications in optical interconnects at telecommunications wavelengths, the silicon nanophotonic integrated circuit platform has recently proven its merits for working with mid-infrared (mid-IR) optical…

Ultra-sensitive short-wave infrared (SWIR) photon detection is a crucial aspect of ongoing research in quantum technology. However, developing such detectors on a CMOS-compatible silicon technological platform has been challenging due to…

Applied Physics · Physics 2024-11-15 P. Sudha , S. Miyagawa , A. Samanta , D. Moraru

Shortwave-infrared(SWIR) spectral information, ranging from 1 {\mu}m to 2.5{\mu}m, overcomes the limitations of traditional color cameras in acquiring scene information. However, conventional SWIR hyperspectral imaging systems face…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Linqiang Li , Jinglei Hao , Yongqiang Zhao , Pan Liu , Haofang Yan , Ziqin Zhang , Seong G. Kong

Single-pixel imaging, originally developed in light optics, facilitates fast three-dimensional sample reconstruction, as well as probing with light wavelengths undetectable by conventional multi-pixel detectors. However, the spatial…

Mid-InfraRed spectroscopy is a promising label-free technique that can offer insights into morphological and pathological alterations in biological tissues at the molecular level. Owing to the development of the Fourier Transform InfraRed…

Optics · Physics 2026-04-21 Xiangyu Zhao , Yudong Tian , Jingzhu Shao , Chongzhao Wu