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We investigate the dynamics of alginate gels, an important class of biopolymer-based viscoelastic materials, by combining mechanical tests and non-conventional, time-resolved light scattering methods. Two relaxation modes are observed upon…

Soft Condensed Matter · Physics 2013-10-14 Domenico Larobina , Luca Cipelletti

Blends of polymers of different topologies, such as ring and supercoiled, naturally occur in biology and often exhibit emergent viscoelastic properties coveted in industry. However, due to their complexity, along with the difficulty of…

DNA self-assembly is a well-understood nanotechnology to obtain extremely ordered structures from the nanometer to up to the hundred of microns scale. By contrast, DNA hydrogels rely on the disordered assembly of DNA building blocks to…

The mechanical properties of cells are dominated by the cytoskeleton, an interconnected network of long elastic filaments. The connections between the filaments are provided by crosslinking proteins, which constitute, next to the filaments,…

Soft Condensed Matter · Physics 2012-10-09 Claus Heussinger

Cytoskeletal filaments are capable of self-assembly in the absence of externally supplied chemical energy, but the rapid turnover rates essential for their biological function require a constant flux of ATP or GTP hydrolysis. The same is…

Biological Physics · Physics 2019-08-26 Robert Marsland , Jeremy England

The combination of soft responsive particles, such as microgels, with nanoparticles (NPs) yields highly versatile complexes of great potential for applications, from ad-hoc plasmonic sensors to controlled protocols for loading and release.…

The proper design of DNA sequences allows for the formation of well defined supramolecular units with controlled interactions via a consecution of self-assembling processes. Here, we benefit from the controlled DNA self-assembly to…

Soft Condensed Matter · Physics 2018-02-14 Javier Fernandez-Castanon , Francesca Bomboi , Francesco Sciortino

Catch bonds are interactions whose lifetimes increase under mechanical load, a counterintuitive behaviour that underlies diverse biological processes. Translating this mechanism to synthetic materials offers the potential to create systems…

Soft Condensed Matter · Physics 2026-03-11 Wout Laeremans , Wouter G. Ellenbroek

A key objective in DNA-based material science is understanding and precisely controlling the mechanical properties of DNA hydrogels. We perform microrheology measurements using diffusing-wave spectroscopy (DWS) to investigate the…

Time-resolved single-molecule biophysical experiments yield data that contain a wealth of dynamic information, in addition to the equilibrium distributions derived from histograms of the time series. In typical force spectroscopic setups…

Biomolecules · Quantitative Biology 2011-07-14 Michael Hinczewski , Yann von Hansen , Roland R. Netz

Chemical crosslinking of collagen is a general strategy to reproduce macroscale tissue properties in physiological environment. However, simultaneous control of protein conformation, material properties and biofunctionality is highly…

Chemical Physics · Physics 2013-08-27 Giuseppe Tronci , Amanda Doyle , Stephen J. Russell , David J. Wood

Hydrogels have the ability to undergo large deformations and yet fail like brittle materials. The development of biocompatible hydrogels with high strength and toughness is an ongoing challenge in many applications. We crosslinked bovine…

Biological Physics · Physics 2022-03-17 Anshul Shrivastava , Namrata Gundiah

We study numerically the mechanical stability and elasticity properties of duplex DNA molecules within the frame of a network model incorporating microscopic degrees of freedom related with the arrangement of the base pairs. We pay special…

Pattern Formation and Solitons · Physics 2015-06-26 D. Hennig , J. F. R. Archilla

Colloidal molecules are designed to mimic their molecular analogues through their anisotropic shape and interactions. However, current experimental realizations are missing the structural flexibility present in real molecules thereby…

A unified model is constructed to study the recently observed DNA entropic elasticity, cooperative extensibility, and supercoiling property. With the introduction of a new structural parameter (the folding angle $\phi$), bending…

Soft Condensed Matter · Physics 2007-05-23 Zhou Haijun , Zhang Yang , Ou-Yang Zhong-can

Polymer gels with photo-responsive cross-links enable tunable mechanics and surface morphologies, making them promising for adaptive materials. While prior work on coumarin cross-linked gels has focused on photo-mediated events in dilute…

The dynamical arrest of gels is the consequence of a well defined structural phase transition, leading to the formation of a spanning cluster of bonded particles. The dynamical glass transition, instead, is not accompanied by any clear…

Soft Condensed Matter · Physics 2016-07-21 Raffaele Pastore , Antonio de Candia , Anallisa Fierro , Massimo Pica Ciamarra , Antonio Coniglio

Two types of high-strength composite hydrogels possessing the structure of interpenetrating polymer networks were synthesized via free-radical polymerization of acrylamide carried out straight within the matrix of plant or bacterial…

Chemical Physics · Physics 2019-04-02 Alexander Buyanov , Iosif Gofman , Natalya Saprykina

Hydrogel adhesion that can be easily modulated in magnitude, space, and time is desirable in many emerging applications ranging from tissue engineering, and soft robotics, to wearable devices. In synthetic materials, these complex adhesion…

Soft Condensed Matter · Physics 2023-04-07 Zhen Yang , Guangyu Bao , Shuaibing Jiang , Xingwei Yang , Ran Huo , Xiang Ni , Luc Mongeau , Rong Long , Jianyu Li

Liquid crystalline elastomers (LCE) undergo reversible shape changes in response to stimuli, which may enable a wide range of smart applications, such as soft robot, adhesive systems or implantable medical devices. Here we introduce new…

Materials Science · Physics 2020-05-12 Mohand O. Saed , Eugene M. Terentjev