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Programmable lipid nanoparticles, or LNPs, represent a breakthrough in the realm of targeted drug delivery, offering precise spatiotemporal control essential for the treatment of complex diseases such as cancer and genetic disorders. In…

Biomolecules · Quantitative Biology 2024-08-28 Zhaoyu Liu , Jingxun Chen , Mingkun Xu , David H. Gracias , Ken-Tye Yong , Yuanyuan Wei , Ho-Pui Ho

Coronary stents have changed the way in which coronary artery diseases are managed. Although bare-metal stents can be traced back to 1994, long term efficacy of these stents has been shattered by ISR (In-Stent restenosis) and late stent…

Medical Physics · Physics 2016-02-09 Abraham Samuel Finny

Molecular communication (MC), a biologically inspired technology, enables applications in nanonetworks and the Internet of Everything (IoE), with great potential for intra-body systems such as drug delivery, health monitoring, and disease…

Signal Processing · Electrical Eng. & Systems 2025-05-30 Dilara Aktas , Ozgur B. Akan

Jetting dynamics from bursting bubbles play a key role in mediating mass and momentum transport across the air-liquid interface. In marine environments, this phenomenon has drawn considerable attention due to its role in releasing…

Fluid Dynamics · Physics 2025-01-29 Sainath A. Barbhai , Zhengyu Yang , Jie Feng

Removing hazardous particulate and macromolecular contaminants as well as viruses with sizes from a few nm up to the 100-nm-range from water and air is crucial for ensuring sufficient sanitation and hygiene for a growing world population.…

Materials Science · Physics 2021-09-03 Leiming Guo , Yong Wang , Martin Steinhart

Bioceramic porous microspheres are promising substances for dental and orthopedic bone void filling, tissue engineering and drug delivery applications. In this research, the structure and cytocompatibility of bioactive magnesium-calcium…

Biological Physics · Physics 2026-04-21 A. Bolandparvaz Jahromi , E. Salahinejad

This chapter deals with the fundamental properties of polymer nanocomposites (PNC) and their characteristics that play a significant role in deciding their capability for the advanced energy storage device. The various synthesization…

Materials Science · Physics 2018-07-11 Anil Arya , A. L. Sharma

Polymer translocation through a nanopore in a membrane investigated theoretically. Recent experiments on voltage-driven DNA and RNA translocations through a nanopore indicate that the size and geometry of the pore are important factors in…

Statistical Mechanics · Physics 2009-11-07 Elena Slonkina , Anatoly B. Kolomeisky

It is assumed that each nano-robot has a 0.1 micrometers cubed of tankage which is far smaller than the volume of a human red blood cell[6]. Thus, the nano-machines are non-invasive for biomedical applications, such as drug delivery and…

Emerging Technologies · Computer Science 2019-12-24 Ahmad Yousef

This paper studies the mitigation of intersymbol interference in a diffusive molecular communication system using enzymes that freely diffuse in the propagation environment. The enzymes form reaction intermediates with information molecules…

Information Theory · Computer Science 2014-01-21 Adam Noel , Karen C. Cheung , Robert Schober

Hyperbranched block copolymers offer a simpler and more efficient synthesis route compared to more traditional dendritic systems, while still providing exceptional control over surface functionality and self-assembly. This makes them ideal…

Soft Condensed Matter · Physics 2025-06-03 Marios Giannakou , Oleg V. Borisov , Friederike Schmid

On-demand controlled drug delivery is essential for the treatment of a wide range of chronic diseases. As the drug is released at the time when required, its efficacy is boosted and the side effects are minimized. However, so far, drug…

Robotics · Computer Science 2024-03-06 Yangchao Zhou , Moonkwang Jeong , Meng Zhang , Xuexin Duan , Tian Qiu

In this paper, we propose novel modulation techniques using isomers as messenger molecules for nano communication via diffusion. To evaluate achievable rate performance, we compare the proposed techniques with concentration-based and…

Quantitative Methods · Quantitative Biology 2012-01-05 Na-Rae Kim , Chan-Byoung Chae

Tracer-diffusion of small molecules through dense systems of chain polymers is studied within an athermal lattice model, where hard core interactions are taken into account by means of the site exclusion principle. An approximate mapping of…

Soft Condensed Matter · Physics 2009-11-07 O. Durr , T. Volz , W. Dieterich , A. Nitzan

Machine learning, and representation learning in particular, has the potential to facilitate drug discovery by screening billions of compounds. For example, a successful approach is representing the molecules as a graph and utilizing graph…

Quantitative Methods · Quantitative Biology 2023-04-17 Ronen Taub , Tanya Wasserman , Yonatan Savir

Nucleic acids and proteins are not only biologically important polymers: They have recently been recognized as novel functional materials surpassing in many aspects the conventional ones. Although Herculean efforts have been undertaken to…

Soft Condensed Matter · Physics 2010-06-17 Waleed Shinwari , Jamal Deen , Evgeni Starikov , Gianaurelio Cuniberti

We study the surface diffusion of the model cyanobacterium Synechocystis sp. PCC $6803$ during the incipient stages of cell contact with a glass surface in the dilute regime. We observe a twitching motility with alternating immobile…

Despite all the advances achieved in the field of tumor-biology research, in most cases conventional therapies including chemotherapy are still the leading choices. The main disadvantage of these treatments, in addition to the low…

Tissues and Organs · Quantitative Biology 2024-01-25 Paola Sanchez-Moreno , Juan Luis Ortega-Vinuesa , Jose Manuel Peula-Garcia , Juan Antonio Marchal , Houria Boulaiz

Molecular communication (MC) engineering is inspired by the use of chemical signals as information carriers in cell biology. The biological nature of chemical signaling makes MC a promising methodology for interdisciplinary applications…

Emerging Technologies · Computer Science 2020-09-02 Dadi Bi , Apostolos Almpanis , Adam Noel , Yansha Deng , Robert Schober

We examine the budding of a nanoscale particle through a lipid bilayer using molecular dynamics simulations, free energy calculations, and an elastic theory, with the aim of determining the extent to which equilibrium elasticity theory can…

Subcellular Processes · Quantitative Biology 2012-02-22 Teresa Ruiz-Herrero , Enrique Velasco , Michael F. Hagan