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Large language models (LLMs) show promise in healthcare, but hallucinations remain a major barrier to clinical use. We present CHECK, a continuous-learning framework that integrates structured clinical databases with a classifier grounded…

Discharge summaries require extracting critical information from lengthy electronic health records (EHRs), a process that is labor-intensive when performed manually. Large language models (LLMs) can improve generation efficiency; however,…

Computation and Language · Computer Science 2026-05-06 Severin Ye , Xiao Kong , Xiaopeng He , Guangsu Yan , Dongsuk Oh

Clinical decision-making increasingly relies on timely and context-aware access to patient information within Electronic Health Records (EHRs), yet most existing natural language question-answering (QA) systems are evaluated solely on…

Large language models have proliferated across multiple domains in as short period of time. There is however hesitation in the medical and healthcare domain towards their adoption because of issues like factuality, coherence, and…

Computation and Language · Computer Science 2023-11-06 Muhammad Aurangzeb Ahmad , Ilker Yaramis , Taposh Dutta Roy

LLM-based agents have demonstrated strong potential for autonomous machine learning, yet their applicability to health data remains limited. Existing systems often struggle to generalize across heterogeneous health data modalities, rely…

Artificial Intelligence · Computer Science 2026-02-03 Tong Xia , Weibin Li , Gang Liu , Yong Li

Large Language Models (LLMs) are widely used in industry but remain prone to hallucinations, limiting their reliability in critical applications. This work addresses hallucination reduction in consumer grievance chatbots built using LLaMA…

Large language models (LLMs) offer a valuable technology for various applications in healthcare. However, their tendency to hallucinate and the existing reliance on proprietary systems pose challenges in environments concerning critical…

Computation and Language · Computer Science 2025-02-27 Joshua Strong , Qianhui Men , Alison Noble

Despite the rapid advancement of large language models, they remain highly susceptible to generating hallucinations, which significantly hinders their widespread application. Hallucination research requires dynamic and fine-grained…

Computation and Language · Computer Science 2025-04-15 Xu Zhang , Zhifei Liu , Jiahao Wang , Huixuan Zhang , Fan Xu , Junzhe Zhang , Xiaojun Wan

Medical Large Language Models (MLLMs) play a crucial role in ophthalmic diagnosis, holding significant potential to address vision-threatening diseases. However, their accuracy is constrained by hallucinations stemming from limited…

Computation and Language · Computer Science 2025-10-02 Xiaoyu Pan , Yang Bai , Ke Zou , Yang Zhou , Jun Zhou , Huazhu Fu , Yih-Chung Tham , Yong Liu

Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic…

Artificial Intelligence · Computer Science 2025-10-14 Hongjie Zheng , Zesheng Shi , Ping Yi

Large language models (LLMs) have demonstrated exceptional capabilities in planning and tool utilization as autonomous agents, but few have been developed for medical problem-solving. We propose EHRAgent, an LLM agent empowered with a code…

Computation and Language · Computer Science 2024-10-07 Wenqi Shi , Ran Xu , Yuchen Zhuang , Yue Yu , Jieyu Zhang , Hang Wu , Yuanda Zhu , Joyce Ho , Carl Yang , May D. Wang

Trustworthiness in healthcare question-answering (QA) systems is important for ensuring patient safety, clinical effectiveness, and user confidence. As large language models (LLMs) become increasingly integrated into medical settings, the…

Computation and Language · Computer Science 2025-11-04 Yinuo Wang , Baiyang Wang , Robert E. Mercer , Frank Rudzicz , Sudipta Singha Roy , Pengjie Ren , Zhumin Chen , Xindi Wang

The integration of large language models (LLMs) into healthcare IoT systems promises faster decisions and improved medical support. LLMs are also deployed as multi-agent teams to assist AI doctors by debating, voting, or advising on…

Cryptography and Security · Computer Science 2025-12-04 Adeela Bashir , The Anh han , Zia Ush Shamszaman

We introduce ColaCare, a framework that enhances Electronic Health Record (EHR) modeling through multi-agent collaboration driven by Large Language Models (LLMs). Our approach seamlessly integrates domain-specific expert models with LLMs to…

Hallucinations are outputs by Large Language Models (LLMs) that are factually incorrect yet appear plausible [1]. This paper investigates how such hallucinations influence users' trust in LLMs and users' interaction with LLMs. To explore…

Artificial Intelligence · Computer Science 2025-12-11 Adrian Ryser , Florian Allwein , Tim Schlippe

Hallucinations pose a significant challenge to the reliability and alignment of Large Language Models (LLMs), limiting their widespread acceptance beyond chatbot applications. Despite ongoing efforts, hallucinations remain a prevalent…

Computation and Language · Computer Science 2024-02-27 Cem Uluoglakci , Tugba Taskaya Temizel

AI agents are rapidly advancing from passive language models to autonomous systems executing complex, multi-step tasks. Yet their overconfidence in failure remains a fundamental barrier to deployment in high-stakes settings. Existing…

Artificial Intelligence · Computer Science 2026-01-23 Jiaxin Zhang , Caiming Xiong , Chien-Sheng Wu

Large language models (LLMs) are prone to hallucinations, i.e., statements unsupported by the input or training data, hindering reliable deployment. In parallel, numerous uncertainty estimation (UE) methods have been proposed to quantify…

Computation and Language · Computer Science 2026-05-27 Yedidia Agnimo , Anna Korba , Annabelle Blangero , Nicolas Chesneau , Karteek Alahari

Medical Large Language Models (MLLMs) have demonstrated potential in healthcare applications, yet their propensity for hallucinations -- generating medically implausible or inaccurate information -- presents substantial risks to patient…

Computation and Language · Computer Science 2025-04-01 Kaiwen Zuo , Yirui Jiang

To mitigate the impact of hallucination nature of LLMs, many studies propose detecting hallucinated generation through uncertainty estimation. However, these approaches predominantly operate at the sentence or paragraph level, failing to…

Computation and Language · Computer Science 2025-09-05 Min-Hsuan Yeh , Max Kamachee , Seongheon Park , Yixuan Li
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