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Related papers: Enhancing Chemical Explainability Through Counterf…

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Computer-driven molecular design combines the principles of chemistry, physics, and artificial intelligence to identify novel chemical compounds and materials with desired properties for a specific application. In particular,…

Chemical Physics · Physics 2023-09-04 Alessio Fallani , Leonardo Medrano Sandonas , Alexandre Tkatchenko

With the increasing deployment of machine learning systems in practice, transparency and explainability have become serious issues. Contrastive explanations are considered to be useful and intuitive, in particular when it comes to…

Machine Learning · Computer Science 2021-01-05 André Artelt , Barbara Hammer

Explainable Artificial Intelligence and Formal Argumentation have received significant attention in recent years. Argumentation-based systems often lack explainability while supporting decision-making processes. Counterfactual and…

Artificial Intelligence · Computer Science 2024-05-08 Gianvincenzo Alfano , Sergio Greco , Francesco Parisi , Irina Trubitsyna

Predicting the physico-chemical properties of pure substances and mixtures is a central task in thermodynamics. Established prediction methods range from fully physics-based ab-initio calculations, which are only feasible for very simple…

Machine Learning · Computer Science 2024-12-02 Johannes Zenn , Dominik Gond , Fabian Jirasek , Robert Bamler

Counterfactual inference is a powerful tool, capable of solving challenging problems in high-profile sectors. To perform counterfactual inference, one requires knowledge of the underlying causal mechanisms. However, causal mechanisms cannot…

Machine Learning · Computer Science 2023-01-23 Athanasios Vlontzos , Bernhard Kainz , Ciaran M. Gilligan-Lee

With the increasing impact of algorithmic decision-making on human lives, the interpretability of models has become a critical issue in machine learning. Counterfactual explanation is an important method in the field of interpretable…

Machine Learning · Computer Science 2024-07-17 Ao Xu , Tieru Wu

Crystal graph neural networks are widely applicable in modeling experimentally synthesized compounds and hypothetical materials with unknown synthesizability. In contrast, structure-agnostic predictive algorithms allow exploring previously…

Materials Science · Physics 2025-11-06 Ivan Rubtsov , Ivan Dudakov , Yuri Kuratov , Vadim Korolev

Counterfactual explanation methods have recently received significant attention for explaining CNN-based image classifiers due to their ability to provide easily understandable explanations that align more closely with human reasoning.…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Syed Ali Tariq , Tehseen Zia

Counterfactual explanations are emerging as an attractive option for providing recourse to individuals adversely impacted by algorithmic decisions. As they are deployed in critical applications (e.g. law enforcement, financial lending), it…

Machine Learning · Computer Science 2021-11-05 Dylan Slack , Sophie Hilgard , Himabindu Lakkaraju , Sameer Singh

The complexity of modern electro-mechanical systems require the development of sophisticated diagnostic methods like anomaly detection capable of detecting deviations. Conventional anomaly detection approaches like signal processing and…

Machine Learning · Computer Science 2025-01-07 Abhishek Srinivasan , Varun Singapuri Ravi , Juan Carlos Andresen , Anders Holst

Explainability for machine learning models has gained considerable attention within the research community given the importance of deploying more reliable machine-learning systems. In computer vision applications, generative counterfactual…

Machine Learning · Computer Science 2021-11-12 Pau Rodriguez , Massimo Caccia , Alexandre Lacoste , Lee Zamparo , Issam Laradji , Laurent Charlin , David Vazquez

Molecular representation is a critical element in our understanding of the physical world and the foundation for modern molecular machine learning. Previous molecular machine learning models have employed strings, fingerprints, global…

Machine Learning · Computer Science 2025-05-28 Daniil A. Boiko , Thiago Reschützegger , Benjamin Sanchez-Lengeling , Samuel M. Blau , Gabe Gomes

Neural network interpretability is a vital component for applications across a wide variety of domains. In such cases it is often useful to analyze a network which has already been trained for its specific purpose. In this work, we develop…

Machine Learning · Computer Science 2019-11-19 Lawrence Phillips , Garrett Goh , Nathan Hodas

Material scientists are increasingly adopting the use of machine learning (ML) for making potentially important decisions, such as, discovery, development, optimization, synthesis and characterization of materials. However, despite ML's…

Computational Physics · Physics 2019-03-12 Bhavya Kailkhura , Brian Gallagher , Sookyung Kim , Anna Hiszpanski , T. Yong-Jin Han

Despite their enormous predictive power, machine learning models are often unsuitable for applications in regulated industries such as finance, due to their limited capacity to provide explanations. While model-agnostic frameworks such as…

Machine Learning · Statistics 2025-11-03 Joshua S. Harvey , Guanchao Feng , Sai Anusha Meesala , Tina Zhao , Dhagash Mehta

As machine learning models are increasingly used in critical decision-making settings (e.g., healthcare, finance), there has been a growing emphasis on developing methods to explain model predictions. Such \textit{explanations} are used to…

Machine Learning · Computer Science 2021-06-29 Dylan Slack , Sophie Hilgard , Sameer Singh , Himabindu Lakkaraju

Counterfactuals are a concept inherited from the field of logic and in general attain to the existence of causal relations between sentences or events. In particular, this concept has been introduced also in the context of interpretability…

Systems and Control · Electrical Eng. & Systems 2025-01-23 Pierluigi Francesco De Paola , Jared Miller , Alessandro Borri , Alessia Paglialonga , Fabrizio Dabbene

We develop a novel method for counterfactual analysis based on observational data using prediction intervals for units under different exposures. Unlike methods that target heterogeneous or conditional average treatment effects of an…

Statistics Theory · Mathematics 2018-07-18 Dave Zachariah , Petre Stoica

Molecular property prediction, crucial for early drug candidate screening and optimization, has seen advancements with deep learning-based methods. While deep learning-based methods have advanced considerably, they often fall short in fully…

Biomolecules · Quantitative Biology 2024-07-01 Taojie Kuang , Yiming Ren , Zhixiang Ren

Reliable predictions of the behaviour of chemical systems are essential across many industries, from nanoscale engineering over validation of advanced materials to nanotoxicity assessment in health and medicine. For the future we therefore…

Chemical Physics · Physics 2021-03-05 Judith B. Rommel