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Anomaly detection aims at identifying deviant samples from the normal data distribution. Contrastive learning has provided a successful way to sample representation that enables effective discrimination on anomalies. However, when…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Gaoang Wang , Yibing Zhan , Xinchao Wang , Mingli Song , Klara Nahrstedt

Supervised Contrastive Loss (SCL) is popular in visual representation learning. Given an anchor image, SCL pulls two types of positive samples, i.e., its augmentation and other images from the same class together, while pushes negative…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Shiyu Xuan , Shiliang Zhang

Trajectory inference is used to order single-cell omics data along a path that reflects a continuous transition between cells. This approach is useful for studying processes like cell differentiation, where a stem cell matures into a…

Quantitative Methods · Quantitative Biology 2025-12-23 Alexandre Hutton , Jesse G. Meyer

Hyperspectral image (HSI) classification techniques have been intensively studied and a variety of models have been developed. However, these HSI classification models are confined to pocket models and unrealistic ways of dataset…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Quanwei Liu , Yanni Dong , Tao Huang , Lefei Zhang , Bo Du

The clustering of data into physically meaningful subsets often requires assumptions regarding the number, size, or shape of the subgroups. Here, we present a new method, simultaneous coherent structure coloring (sCSC), which accomplishes…

Machine Learning · Statistics 2019-11-26 Brooke E. Husic , Kristy L. Schlueter-Kuck , John O. Dabiri

Semi-supervised learning utilizes insights from unlabeled data to improve model generalization, thereby reducing reliance on large labeled datasets. Most existing studies focus on limited samples and fail to capture the overall data…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Xiuzhen Guo , Lianyuan Yu , Ji Shi , Na Lei , Hongxiao Wang

Real-world data typically follow a long-tailed distribution, where a few majority categories occupy most of the data while most minority categories contain a limited number of samples. Classification models minimizing cross-entropy struggle…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Jianggang Zhu , Zheng Wang , Jingjing Chen , Yi-Ping Phoebe Chen , Yu-Gang Jiang

Contrastive learning (CL) has emerged as a powerful paradigm for learning transferable representations without the reliance on large labeled datasets. Its ability to capture intrinsic similarities and differences among data samples has led…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Debashis Gupta , Aditi Golder , Rongkhun Zhu , Kangning Cui , Wei Tang , Fan Yang , Ovidiu Csillik , Sarra Alaqahtani , V. Paul Pauca

Contrastive, self-supervised learning (SSL) is used to train a model that predicts cancer type from miRNA, mRNA or RPPA expression data. This model, a pretrained FT-Transformer, is shown to outperform XGBoost and CatBoost, standard…

Machine Learning · Computer Science 2023-11-17 Christian John Hurry , Emma Slade

Large language models (LLMs) have demonstrated remarkable advancements, primarily due to their capabilities in modeling the hidden relationships within text sequences. This innovation presents a unique opportunity in the field of life…

Genomics · Quantitative Biology 2024-12-25 Cong Li , Qingqing Long , Yuanchun Zhou , Meng Xiao

Controlling false positives (Type I errors) through statistical hypothesis testing is a foundation of modern scientific data analysis. Existing causal structure discovery algorithms either do not provide Type I error control or cannot scale…

Methodology · Statistics 2025-12-29 James Leiner , Brian Manzo , Aaditya Ramdas , Wesley Tansey

In this paper, we introduce InSQuAD, designed to enhance the performance of In-Context Learning (ICL) models through Submodular Mutual Information} (SMI) enforcing Quality and Diversity among in-context exemplars. InSQuAD achieves this…

Machine Learning · Computer Science 2025-08-29 Souradeep Nanda , Anay Majee , Rishabh Iyer

Recent advances in spatial omics technologies have revolutionized our ability to study biological systems with unprecedented resolution. By preserving the spatial context of molecular measurements, these methods enable comprehensive mapping…

Quantitative Methods · Quantitative Biology 2025-09-18 Zhiwei Fan , Tiangang Wang , Kexin Huang , Binwu Ying , Xiaobo Zhou

We introduce a model for describing the dynamics of large numbers of interacting cells. The fundamental dynamical variables in the model are sub-cellular elements, which interact with each other through phenomenological intra- and…

Quantitative Methods · Quantitative Biology 2007-05-23 T. J. Newman

Online Class-Incremental continual Learning (OCIL) addresses the challenge of continuously learning from a single-channel data stream, adapting to new tasks while mitigating catastrophic forgetting. Recently, Mutual Information (MI)-based…

Machine Learning · Computer Science 2024-07-29 Huan Zhang , Fan Lyu , Shenghua Fan , Yujin Zheng , Dingwen Wang

In deepfake detection, the varying degrees of compression employed by social media platforms pose significant challenges for model generalization and reliability. Although existing methods have progressed from single-modal to multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Ching-Yi Lai , Chih-Yu Jian , Pei-Cheng Chuang , Chia-Ming Lee , Chih-Chung Hsu , Chiou-Ting Hsu , Chia-Wen Lin

Detectingandsegmentingobjectswithinwholeslideimagesis essential in computational pathology workflow. Self-supervised learning (SSL) is appealing to such annotation-heavy tasks. Despite the extensive benchmarks in natural images for dense…

Computer Vision and Pattern Recognition · Computer Science 2022-07-15 Jiawei Yang , Hanbo Chen , Yuan Liang , Junzhou Huang , Lei He , Jianhua Yao

Single-cell RNA sequencing (scRNA-seq) reveals cell heterogeneity, with cell clustering playing a key role in identifying cell types and marker genes. Recent advances, especially graph neural networks (GNNs)-based methods, have…

Genomics · Quantitative Biology 2025-10-03 Ping Xu , Zhiyuan Ning , Pengjiang Li , Wenhao Liu , Pengyang Wang , Jiaxu Cui , Yuanchun Zhou , Pengfei Wang

Citrus, as one of the most economically important fruit crops globally, suffers severe yield depressions due to various diseases. Accurate disease detection and classification serve as critical prerequisites for implementing targeted…

Computer Vision and Pattern Recognition · Computer Science 2025-07-16 Jun Chen , Yonghua Yu , Weifu Li , Yaohui Chen , Hong Chen

Advances in single-cell omics allow for unprecedented insights into the transcription profiles of individual cells. When combined with large-scale perturbation screens, through which specific biological mechanisms can be targeted, these…

Machine Learning · Computer Science 2023-10-24 Alejandro Tejada-Lapuerta , Paul Bertin , Stefan Bauer , Hananeh Aliee , Yoshua Bengio , Fabian J. Theis