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In recent years, the growing interest in Large Language Models (LLMs) has significantly advanced prompt engineering, transitioning from manual design to model-based optimization. Prompts for LLMs generally comprise two components: the…

Computation and Language · Computer Science 2025-10-09 Qinhao Zhou , Xiang Xiang , Kun He , John E. Hopcroft

The field of automated algorithm design has been advanced by frameworks such as EoH, FunSearch, and Reevo. Yet, their focus on algorithm evolution alone, neglecting the prompts that guide them, limits their effectiveness with LLMs,…

Neural and Evolutionary Computing · Computer Science 2025-12-11 Shipeng Cen , Ying Tan

Large language models (LLMs) often exhibit limited performance on domain-specific tasks due to the natural disproportionate representation of specialized information in their training data and the static nature of these datasets. Knowledge…

Computation and Language · Computer Science 2025-09-30 Chaojun Nie , Jun Zhou , Guanxiang Wang , Shisong Wu , Zichen Wang

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

Designing optimization approaches, whether heuristic or meta-heuristic, usually demands extensive manual intervention and has difficulty generalizing across diverse problem domains. The combination of Large Language Models (LLMs) and…

Neural and Evolutionary Computing · Computer Science 2024-10-29 He Yu , Jing Liu

Large Language Models (LLMs) have demonstrated remarkable efficacy in text embedding, yet current adaptation methods like LoRA face significant bottlenecks in computational efficiency and cross-architecture transferability. Whenever a new…

Computation and Language · Computer Science 2026-05-28 Yu-Che Tsai , Kuan-Yu Chen , Yuan-Hao Chen , Yu-Han Chang , Ching-Yu Tsai , Yu-Hsiang Chuang , Shou-De Lin

Continual Learning (CL) enables machine learning models to learn from continuously shifting new training data in absence of data from old tasks. Recently, pretrained vision transformers combined with prompt tuning have shown promise for…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 Anurag Roy , Riddhiman Moulick , Vinay K. Verma , Saptarshi Ghosh , Abir Das

We present a refined approach to biomedical question-answering (QA) services by integrating large language models (LLMs) with Multi-BERT configurations. By enhancing the ability to process and prioritize vast amounts of complex biomedical…

Computation and Language · Computer Science 2024-10-18 Cheng Qian , Xianglong Shi , Shanshan Yao , Yichen Liu , Fengming Zhou , Zishu Zhang , Junaid Akram , Ali Braytee , Ali Anaissi

Integrating Large Language Models (LLMs) and Evolutionary Computation (EC) represents a promising avenue for advancing artificial intelligence by combining powerful natural language understanding with optimization and search capabilities.…

Neural and Evolutionary Computing · Computer Science 2025-05-22 Dikshit Chauhan , Bapi Dutta , Indu Bala , Niki van Stein , Thomas Bäck , Anupam Yadav

This research paper investigates the application of Large Language Models (LLMs) in healthcare, specifically focusing on enhancing medical decision support through Retrieval-Augmented Generation (RAG) integrated with hospital-specific data…

Computation and Language · Computer Science 2025-05-07 Mohammad Shoaib Ansari , Mohd Sohail Ali Khan , Shubham Revankar , Aditya Varma , Anil S. Mokhade

Molecule generation and optimization is a fundamental task in chemical domain. The rapid development of intelligent tools, especially large language models (LLMs) with powerful knowledge reserves and interactive capabilities, has provided…

Machine Learning · Computer Science 2026-02-10 Haoran Liu , Zheni Zeng , Yukun Yan , Yuxuan Chen , Yunduo Xiao

Effective prompt engineering is critical to realizing the promised productivity gains of large language models (LLMs) in knowledge-intensive tasks. Yet, many users struggle to craft prompts that yield high-quality outputs, limiting the…

Human-Computer Interaction · Computer Science 2025-10-02 Niklas Gutheil , Valentin Mayer , Leopold Müller , Jörg Rommelt , Niklas Kühl

The increasing depth of parametric domain knowledge in large language models (LLMs) is fueling their rapid deployment in real-world applications. Understanding model vulnerabilities in high-stakes and knowledge-intensive tasks is essential…

Computation and Language · Computer Science 2024-12-02 R. Patrick Xian , Alex J. Lee , Satvik Lolla , Vincent Wang , Qiming Cui , Russell Ro , Reza Abbasi-Asl

The advancement of large language models (LLMs) has opened new frontiers in natural language processing, particularly in specialized domains like healthcare. In this paper, we propose the Incremental Curriculum-Based Fine-Tuning (ICFT)…

Computation and Language · Computer Science 2025-02-04 Robert Long , Eric Gonzalez , Harrison Fuller

Synthetic data has become a cornerstone for scaling large language models, yet its multilingual use remains bottlenecked by translation-based prompts. This strategy inherits English-centric framing and style and neglects cultural…

Computation and Language · Computer Science 2025-10-23 David Mora , Viraat Aryabumi , Wei-Yin Ko , Sara Hooker , Julia Kreutzer , Marzieh Fadaee

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

Computation and Language · Computer Science 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Medical Vision-Language Models (Med-VLMs) have demonstrated remarkable performance across diverse medical imaging tasks by leveraging large-scale image-text pretraining. However, their confidence calibration is largely unexplored, and so…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Abhishek Basu , Fahad Shamshad , Ashshak Sharifdeen , Karthik Nandakumar , Muhammad Haris Khan

This paper investigates how prompt engineering techniques impact both accuracy and confidence elicitation in Large Language Models (LLMs) applied to medical contexts. Using a stratified dataset of Persian board exam questions across…

Computers and Society · Computer Science 2025-06-03 Nariman Naderi , Zahra Atf , Peter R Lewis , Aref Mahjoub far , Seyed Amir Ahmad Safavi-Naini , Ali Soroush

Large language models (LLMs) have demonstrated impressive success in a wide range of natural language processing (NLP) tasks due to their extensive general knowledge of the world. Recent works discovered that the performance of LLMs is…

Computation and Language · Computer Science 2024-11-25 Yuze Liu , Tingjie Liu , Tiehua Zhang , Youhua Xia , Jinze Wang , Zhishu Shen , Jiong Jin , Fei Richard Yu

We propose a novel prompt design paradigm that challenges conventional wisdom in large language model (LLM) prompting. While conventional wisdom prioritizes well-crafted instructions and demonstrations for in-context learning (ICL), we show…

Artificial Intelligence · Computer Science 2025-06-24 Jianyu Wang , Zhiqiang Hu , Lidong Bing