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The EMI (Extracellular-Membrane-Intracellular) model describes electrical activity in excitable tissue, where the extracellular and intracellular spaces and cellular membrane are explicitly represented. The model couples a system of partial…

Numerical Analysis · Mathematics 2023-07-06 Nanna Berre , Marie E. Rognes , Andre Massing

Over the past decade, U-Net has been the dominant architecture in medical image segmentation, leading to the development of thousands of U-shaped variants. Despite its widespread adoption, there is still no comprehensive benchmark to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Fenghe Tang , Chengqi Dong , Wenxin Ma , Zikang Xu , Heqin Zhu , Zihang Jiang , Rongsheng Wang , Yuhao Wang , Chenxu Wu , Shaohua Kevin Zhou

Cryo-electron microscopy (cryo-EM) is a powerful imaging technique for reconstructing three-dimensional molecular structures from noisy tomographic projection images of randomly oriented particles. We introduce a new data fusion framework,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Joe Kileel , Oscar Mickelin , Amit Singer , Sheng Xu

Accurate segmentation and measurement of lithography scanning electron microscope (SEM) images are crucial for ensuring precise process control, optimizing device performance, and advancing semiconductor manufacturing yield. Lithography…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Xinyu He , Botong Zhao , Bingbing Li , Shujing Lyu , Jiwei Shen , Yue Lu

Deep learning methods have played a more and more important role in hyperspectral image classification. However, the general deep learning methods mainly take advantage of the information of sample itself or the pairwise information between…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Zhiqiang Gong , Weidong Hu , Xiaoyong Du , Ping Zhong , Panhe Hu

Current deep networks are very data-hungry and benefit from training on largescale datasets, which are often time-consuming to collect and annotate. By contrast, synthetic data can be generated infinitely using generative models such as…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Weijia Wu , Yuzhong Zhao , Hao Chen , Yuchao Gu , Rui Zhao , Yefei He , Hong Zhou , Mike Zheng Shou , Chunhua Shen

Eyebrows play a critical role in facial expression and appearance. Although the 3D digitization of faces is well explored, less attention has been drawn to 3D eyebrow modeling. In this work, we propose EMS, the first learning-based…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Chenghong Li , Leyang Jin , Yujian Zheng , Yizhou Yu , Xiaoguang Han

Recent advances in training deep (multi-layer) architectures have inspired a renaissance in neural network use. For example, deep convolutional networks are becoming the default option for difficult tasks on large datasets, such as image…

Neural and Evolutionary Computing · Computer Science 2016-02-17 Mark D. McDonnell , Migel D. Tissera , Tony Vladusich , André van Schaik , Jonathan Tapson

If we are ever to unravel the mysteries of brain function at its most fundamental level, we will need a precise understanding of how its component neurons connect to each other. Electron Microscopes (EM) can now provide the nanometer…

Computer Vision and Pattern Recognition · Computer Science 2016-09-28 Pascal Fua , Graham Knott

Semantic segmentation of electron microscopy (EM) is an essential step to efficiently obtain reliable morphological statistics. Despite the great success achieved using deep convolutional neural networks (CNNs), they still produce coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-01-11 Zhimin Yuan , Xiaofen Ma , Jiajin Yi , Zhengrong Luo , Jialin Peng

Electron microscopy (EM) has been instrumental in our understanding of biological systems ranging from subcellular structures to complex organisms. Although EM reveals cellular morphology with nanoscale resolution, it does not provide…

Comprehensive, synapse-resolution imaging of the brain will be crucial for understanding neuronal computations and function. In connectomics, this has been the sole purview of volume electron microscopy (EM), which entails an excruciatingly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Yicong Li , Yaron Meirovitch , Aaron T. Kuan , Jasper S. Phelps , Alexandra Pacureanu , Wei-Chung Allen Lee , Nir Shavit , Lu Mi

Understanding complex phenomena often requires analyzing high-dimensional data to uncover emergent properties that arise from multifactorial interactions. Here, we present EMUSES (Emerging-properties Mapping Using Spatial Embedding…

Emerging Technologies · Computer Science 2024-06-21 Chris Foulon , Marcela Ovando-Tellez , Lia Talozzi , Maurizio Corbetta , Anna Matsulevits , Michel Thiebaut de Schotten

This study investigates the effectiveness of several machine learning algorithms for static malware detection using the EMBER dataset, which contains feature representations of Portable Executable (PE) files. We evaluate eight…

Cryptography and Security · Computer Science 2025-07-28 Md Min-Ha-Zul Abedin , Tazqia Mehrub

3D image segmentation plays an important role in biomedical image analysis. Many 2D and 3D deep learning models have achieved state-of-the-art segmentation performance on 3D biomedical image datasets. Yet, 2D and 3D models have their own…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Hao Zheng , Yizhe Zhang , Lin Yang , Peixian Liang , Zhuo Zhao , Chaoli Wang , Danny Z. Chen

Cardiovascular disease (CVD) is a major pediatric health burden, and early screening is of critical importance. Electrocardiography (ECG), as a noninvasive and accessible tool, is well suited for this purpose. This paper presents the first…

Signal Processing · Electrical Eng. & Systems 2025-10-07 Yiqiao Chen

Single-particle cryo-electron microscopy (cryo-EM) has recently joined X-ray crystallography and NMR spectroscopy as a high-resolution structural method to resolve biological macromolecules. In a cryo-EM experiment, the microscope produces…

Information Theory · Computer Science 2022-10-28 Tamir Bendory , Nicolas Boumal , William Leeb , Eitan Levin , Amit Singer

Microscopy images contain rich information about how cells respond to perturbations, making them essential to applications like drug screening. To quantify images, researchers often use representation extraction methods, and recent years…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Emre Hayir , Lorin Crawford , Alex X. Lu

Constructing of molecular structural models from Cryo-Electron Microscopy (Cryo-EM) density volumes is the critical last step of structure determination by Cryo-EM technologies. Methods have evolved from manual construction by structural…

Machine Learning · Computer Science 2019-02-13 Kui Xu , Zhe Wang , Jiangping Shi , Hongsheng Li , Qiangfeng Cliff Zhang

State-of-the-art electron microscopes such as scanning electron microscopes (SEM), scanning transmission electron microscopes (STEM) and transmission electron microscopes (TEM) have become increasingly sophisticated. However, the quality of…

Computational Physics · Physics 2023-03-31 I. Lobato , T. Friedrich , S. Van Aert