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Link and sign prediction in complex networks bring great help to decision-making and recommender systems, such as in predicting potential relationships or relative status levels. Many previous studies focused on designing the special…

Physics and Society · Physics 2021-08-04 Chuang Liu , Shimin Yu , Ying Huang , Zi-Ke Zhang

Determining the interaction partners among protein/domain families poses hard computational problems, in particular in the presence of paralogous proteins. Available approaches aim to identify interaction partners among protein/domain…

Populations and Evolution · Quantitative Biology 2015-01-14 Iman Hajirasouliha , Alexander Schönhuth , David Juan , Alfonso Valencia , S. Cenk Sahinalp

We present a novel dual-head deep learning architecture for protein-protein interaction modeling that enables simultaneous prediction of binding affinity ($\Delta G$) and mutation-induced affinity changes ($\Delta\Delta G$) using only…

Quantitative Methods · Quantitative Biology 2025-09-30 Supantha Dey , Ratul Chowdhury

Recent advancements in physics-informed neural networks (PINNs) and their variants have garnered substantial focus from researchers due to their effectiveness in solving both forward and inverse problems governed by differential equations.…

Machine Learning · Computer Science 2026-01-06 Shivani Saini , Ramesh Kumar Vats , Arup Kumar Sahoo

Physics-informed neural networks (PINNs) are a promising approach that combines the power of neural networks with the interpretability of physical modeling. PINNs have shown good practical performance in solving partial differential…

Statistics Theory · Mathematics 2026-01-26 Nathan Doumèche , Gérard Biau , Claire Boyer

Originating in quantum physics, tensor networks (TNs) have been widely adopted as exponential machines and parameter decomposers for recognition tasks. Typical TN models, such as Matrix Product States (MPS), have not yet achieved successful…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Chang Nie , Junfang Chen , Yajie Chen

One challenge of physics is to explain how collective properties arise from microscopic interactions. Indeed, interactions form the building blocks of almost all physical theories and are described by polynomial terms in the action. The…

Disordered Systems and Neural Networks · Physics 2023-05-03 Claudia Merger , Alexandre René , Kirsten Fischer , Peter Bouss , Sandra Nestler , David Dahmen , Carsten Honerkamp , Moritz Helias

Accurate prediction of vehicle collision dynamics is crucial for advanced safety systems and post-impact control applications, yet existing methods face inherent trade-offs among computational efficiency, prediction accuracy, and data…

Systems and Control · Electrical Eng. & Systems 2025-10-16 Yangye Jiang , Jiachen Wang , Daofei Li

Decision trees are powerful for predictive modeling but often suffer from high variance when modeling continuous relationships. While algorithms like Multivariate Adaptive Regression Splines (MARS) excel at capturing such continuous…

Machine Learning · Statistics 2024-10-10 William Pattie , Arvind Krishna

In this study, we employ a conventional deep neural network (NN) framework integrated with physics-based constraints to predict charged hadron multiplicity ($N_{\text{ch}}$) in heavy-ion collisions. The goal is to assess the performance of…

High Energy Physics - Phenomenology · Physics 2026-05-07 Akash Das , Satya Ranjan Nayak , B. K. Singh

Physics-Informed Neural Networks (PINNs) are a class of deep learning models aiming to approximate solutions of PDEs by training neural networks to minimize the residual of the equation. Focusing on non-equilibrium fluctuating systems, we…

Machine Learning · Computer Science 2025-09-25 Javier Castro , Benjamin Gess

Specific protein-protein interactions are crucial in the cell, both to ensure the formation and stability of multi-protein complexes, and to enable signal transduction in various pathways. Functional interactions between proteins result in…

Biological Physics · Physics 2016-11-21 Anne-Florence Bitbol , Robert S. Dwyer , Lucy J. Colwell , Ned S. Wingreen

Physics-informed neural networks (PINNs) have emerged as a promising approach to solving partial differential equations (PDEs) using neural networks, particularly in data-scarce scenarios, due to their unsupervised training capability.…

Machine Learning · Computer Science 2025-03-25 Edgar Torres , Jonathan Schiefer , Mathias Niepert

We introduce Graph-Induced Sum-Product Networks (GSPNs), a new probabilistic framework for graph representation learning that can tractably answer probabilistic queries. Inspired by the computational trees induced by vertices in the context…

Machine Learning · Computer Science 2024-02-19 Federico Errica , Mathias Niepert

The inverse statistical problem of finding direct interactions in complex networks is difficult. In the natural sciences, well-controlled perturbation experiments are widely used to probe the structure of complex networks. However, our…

Disordered Systems and Neural Networks · Physics 2019-10-24 Jialong Jiang , David A. Sivak , Matt Thomson

Navigating dense and dynamic environments poses a significant challenge for autonomous driving systems, owing to the intricate nature of multimodal interaction, wherein the actions of various traffic participants and the autonomous vehicle…

Robotics · Computer Science 2024-08-29 Tong Li , Lu Zhang , Sikang Liu , Shaojie Shen

PPI network alignment aims to find topological and functional similarities between networks of different species. Several alignment approaches have been proposed. Each of these approaches relies on a different alignment method and uses…

Quantitative Methods · Quantitative Biology 2019-11-25 Sarra Ghanjeti

Physics-informed neural networks (PINNs) provide a powerful framework for learning governing equations of dynamical systems from data. Biologically-informed neural networks (BINNs) are a variant of PINNs that preserve the known differential…

Machine Learning · Computer Science 2026-04-21 William Lavery , Jodie A. Cochrane , Christian Olesen , Dagim S. Tadele , John T. Nardini , Sara Hamis

In this paper, we analyze several neural network designs (and their variations) for sentence pair modeling and compare their performance extensively across eight datasets, including paraphrase identification, semantic textual similarity,…

Computation and Language · Computer Science 2018-08-24 Wuwei Lan , Wei Xu

The challenge of missing data remains a significant obstacle across various scientific domains, necessitating the development of advanced imputation techniques that can effectively address complex missingness patterns. This study introduces…

Machine Learning · Computer Science 2025-01-22 Harsh Joshi , Rajeshwari Mistri , Manasi Mali , Nachiket Kapure , Parul Kumari