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Objective: Clinical implementation of deformable image registration (DIR) requires voxel-based spatial accuracy metrics such as manually identified landmarks, which are challenging to implement for highly mobile gastrointestinal (GI)…
The formation of biomolecular materials via dynamical interfacial processes such as self-assembly and fusion, for diverse compositions and external conditions, can be efficiently probed using ensemble Molecular Dynamics. However, this…
Despite the recent advances of deep learning algorithms in medical imaging, the automatic segmentation algorithms for kidneys in MRI exams are still scarce. Automated segmentation of kidneys in Magnetic Resonance Imaging (MRI) exams are…
Foundation models are rapidly being developed for computational pathology applications. However, it remains an open question which factors are most important for downstream performance with data scale and diversity, model size, and training…
Accurately registering breast MR images from different time points enables the alignment of anatomical structures and tracking of tumor progression, supporting more effective breast cancer detection, diagnosis, and treatment planning.…
Efficiently quantifying renal structures can provide distinct spatial context and facilitate biomarker discovery for kidney morphology. However, the development and evaluation of the transformer model to segment the renal cortex, medulla,…
Normalizing flows have been successfully modeling a complex probability distribution as an invertible transformation of a simple base distribution. However, there are often applications that require more than invertibility. For instance,…
Proprietary workflow modeling languages such as Smart Forms & Smart Flow hamper interoperability and reuse because they lock process knowledge into closed formats. To address this vendor lock-in and ease migration to open standards, we…
Early and accurate diagnosis and lesion localization of bone infections are crucial for clinical treatment. PET-CT integrates anatomical information from CT with metabolic information from PET, making it an important imaging modality for…
Fitting multi-exponential models to Diffusion MRI (dMRI) data has always been challenging due to various underlying complexities. In this work, we introduce a novel and robust fitting framework for the standard two-compartment IVIM…
Deep-learning techniques have been used widely to alleviate the labour-intensive and time-consuming manual annotation required for pixel-level tissue characterization. Our previous study introduced an efficient single dynamic network -…
Radiological imaging of prostate is becoming more popular among researchers and clinicians in searching for diseases, primarily cancer. Scans might be acquired at different times, with patient movement between scans, or with different…
Deep learning has revolutionized medical and biological imaging, particularly in segmentation tasks. However, segmenting biological cells remains challenging due to the high variability and complexity of cell shapes. Addressing this…
Understanding the structure of the brain, and how it changes with time and disease, is a core goal of structural neuroimaging. Contemporary approaches to structural brain analysis are dominated by voxel-wise, mass-univariate methods such as…
Automatic integration of whole slide images (WSIs) and gene expression profiles has demonstrated substantial potential in precision clinical diagnosis and cancer progression studies. However, most existing studies focus on individual gene…
Neural networks and particularly Deep learning have been comparatively little studied from the theoretical point of view. Conversely, Mathematical Morphology is a discipline with solid theoretical foundations. We combine these domains to…
The segmentation of kidney layer structures, including cortex, outer stripe, inner stripe, and inner medulla within human kidney whole slide images (WSI) plays an essential role in automated image analysis in renal pathology. However, the…
We present PathoSyn, a unified generative framework for Magnetic Resonance Imaging (MRI) image synthesis that reformulates imaging-pathology as a disentangled additive deviation on a stable anatomical manifold. Current generative models…
Multimodal MRI provides critical complementary information for accurate brain tumor segmentation. However, conventional methods struggle when certain modalities are missing due to issues such as image quality, protocol inconsistencies,…
Current advances in deep learning is leading to human-level accuracy in computer vision tasks such as object classification, localization, semantic segmentation, and instance segmentation. In this paper, we describe a new deep convolutional…