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Related papers: Structure-Aware Temporal Modeling for Chronic Dise…

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With an ever-increasing number of sensors in modern society, spatio-temporal time series forecasting has become a de facto tool to make informed decisions about the future. Most spatio-temporal forecasting models typically comprise distinct…

Machine Learning · Computer Science 2023-03-24 Lars Ødegaard Bentsen , Narada Dilp Warakagoda , Roy Stenbro , Paal Engelstad

Biological foundation models have shown strong performance in single-cell representation learning by applying transformer architectures directly to gene-expression matrices. However, these approaches predominantly operate in static settings…

Machine Learning · Computer Science 2026-05-28 Manuel Dileo , Andrea Sottoriva

Alzheimer's disease is the most common neurodegenerative disease. The aim of this study is to infer structural changes in brain connectivity resulting from disease progression using cortical thickness measurements from a cohort of…

Detecting anomalous edges in dynamic graphs is an important task in many applications over evolving triple-based data, such as social networks, transaction management, and epidemiology. A major challenge with this task is the absence of…

Machine Learning · Computer Science 2025-05-14 Chang Zong , Yueting Zhuang , Jian Shao , Weiming Lu

Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Xi Sheryl Zhang , Lifang He , Kun Chen , Yuan Luo , Jiayu Zhou , Fei Wang

The evolution of sequence modeling architectures, from recurrent neural networks and convolutional models to Transformers and structured state-space models, reflects ongoing efforts to address the diverse temporal dependencies inherent in…

Machine Learning · Computer Science 2025-06-10 Haotian Jiang , Zeyu Bao , Shida Wang , Qianxiao Li

Disease progression modeling aims to characterize and predict how a patient's disease complications worsen over time based on longitudinal electronic health records (EHRs). For diseases such as type 2 diabetes, accurate progression modeling…

Artificial Intelligence · Computer Science 2026-03-31 Tingsong Xiao , Yao An Lee , Zelin Xu , Yupu Zhang , Zibo Liu , Yu Huang , Jiang Bian , Jingchuan Guo , Zhe Jiang

Genetic diseases can be classified according to their modes of inheritance and their underlying molecular mechanisms. Autosomal dominant disorders often result from DNA variants that cause loss-of-function, gain-of-function, or…

Quantitative Methods · Quantitative Biology 2025-06-17 Ali Saadat , Jacques Fellay

Background: Timely, uncertainty-aware forecasting from irregular electronic health records (EHR) can support critical-care decisions, yet most approaches either impute to a grid or sacrifice interpretability. We introduce StructGP, a…

Machine Learning · Computer Science 2026-05-01 Ivan Lerner , Jean Feydy , Alexandre Kalimouttou , Anita Burgun , Francis Bach

Multiple sclerosis is a disease that affects the brain and spinal cord, it can lead to severe disability and has no known cure. The majority of prior work in machine learning for multiple sclerosis has been centered around using Magnetic…

Machine Learning · Computer Science 2023-09-12 Alexander Norcliffe , Lev Proleev , Diana Mincu , Fletcher Lee Hartsell , Katherine Heller , Subhrajit Roy

We introduce deep neural networks for the analysis of anatomical shapes that learn a low-dimensional shape representation from the given task, instead of relying on hand-engineered representations. Our framework is modular and consists of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Benjamin Gutierrez Becker , Ignacio Sarasua , Christian Wachinger

Given a sequence of sets, where each set contains an arbitrary number of elements, the problem of temporal sets prediction aims to predict the elements in the subsequent set. In practice, temporal sets prediction is much more complex than…

Machine Learning · Computer Science 2020-07-09 Le Yu , Leilei Sun , Bowen Du , Chuanren Liu , Hui Xiong , Weifeng Lv

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Time series forecasting plays a crucial role in various applications, particularly in healthcare, where accurate predictions of future health trajectories can significantly impact clinical decision-making. Ensuring transparency and…

Machine Learning · Computer Science 2025-05-22 Jeremy Qin

Predictive Business Process Monitoring (PBPM) aims to forecast future events in ongoing cases based on historical event logs. While Graph Neural Networks (GNNs) are well suited to capture structural dependencies in process data, existing…

Machine Learning · Computer Science 2025-11-25 Fang Wang , Ernesto Damiani

One of the hallmark symptoms of Parkinson's Disease (PD) is the progressive loss of postural reflexes, which eventually leads to gait difficulties and balance problems. Identifying disruptions in brain function associated with gait…

Machine Learning · Computer Science 2023-07-26 Favour Nerrise , Qingyu Zhao , Kathleen L. Poston , Kilian M. Pohl , Ehsan Adeli

Link prediction on graphs has applications spanning from recommender systems to drug discovery. Temporal link prediction (TLP) refers to predicting future links in a temporally evolving graph and adds additional complexity related to the…

Machine Learning · Computer Science 2025-04-18 Ayan Chatterjee , Barbara Ikica , Babak Ravandi , John Palowitch

We propose a versatile framework for survival analysis that combines advanced concepts from statistics with deep learning. The presented framework is based on piecewise exponential models and thereby supports various survival tasks, such as…

Machine Learning · Computer Science 2021-03-02 Philipp Kopper , Sebastian Pölsterl , Christian Wachinger , Bernd Bischl , Andreas Bender , David Rügamer

Clinical outcome or severity prediction from medical images has largely focused on learning representations from single-timepoint or snapshot scans. It has been shown that disease progression can be better characterized by temporal imaging.…

Image and Video Processing · Electrical Eng. & Systems 2022-04-01 Aishik Konwer , Xuan Xu , Joseph Bae , Chao Chen , Prateek Prasanna

Graphs are a central representation in biomedical research, capturing molecular interaction networks, gene regulatory circuits, cell--cell communication maps, and knowledge graphs. Despite their importance, currently there is not a broadly…

Machine Learning · Computer Science 2026-04-09 Sakib Mostafa , Lei Xing , Md. Tauhidul Islam