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Deformable image registration is a crucial step in medical image analysis for finding a non-linear spatial transformation between a pair of fixed and moving images. Deep registration methods based on Convolutional Neural Networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Mingyuan Meng , Lei Bi , Dagan Feng , Jinman Kim

Foundation medical segmentation models, with MedSAM being the most popular, have achieved promising performance across organs and lesions. However, MedSAM still suffers from compromised performance on specific lesions with intricate…

Quantitative Methods · Quantitative Biology 2025-07-16 Kecheng Chen , Xinyu Luo , Tiexin Qin , Jie Liu , Hui Liu , Victor Ho Fun Lee , Hong Yan , Haoliang Li

Deformable image registration aims to precisely align medical images from different modalities or times. Traditional deep learning methods, while effective, often lack interpretability, real-time observability and adjustment capacity during…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Yongtai Zhuo , Yiqing Shen

Cervical cancer is highly preventable, yet persistent barriers to screening limit progress toward elimination goals. Speculum-free devices that integrate imaging and sampling could improve access, particularly in low-resource settings, but…

While deep learning has catalyzed breakthroughs across numerous domains, its broader adoption in clinical settings is inhibited by the costly and time-intensive nature of data acquisition and annotation. To further facilitate medical…

We present a new unsupervised learning algorithm, "FAIM", for 3D medical image registration. With a different architecture than the popular "U-net", the network takes a pair of full image volumes and predicts the displacement fields needed…

Computer Vision and Pattern Recognition · Computer Science 2019-07-02 Dongyang Kuang , Tanya Schmah

Deformable image registration (DIR), aiming to find spatial correspondence between images, is one of the most critical problems in the domain of medical image analysis. In this paper, we present a novel, generic, and accurate diffeomorphic…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Yifan Wu , Tom Z. Jiahao , Jiancong Wang , Paul A. Yushkevich , M. Ani Hsieh , James C. Gee

Recent works in medical image registration have proposed the use of Implicit Neural Representations, demonstrating performance that rivals state-of-the-art learning-based methods. However, these implicit representations need to be optimized…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Louis D. van Harten , Jaap Stoker , Ivana Išgum

Purpose: This study aims to explore training strategies to improve convolutional neural network-based image-to-image deformable registration for abdominal imaging. Methods: Different training strategies, loss functions, and transfer…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Javier Pérez de Frutos , André Pedersen , Egidijus Pelanis , David Bouget , Shanmugapriya Survarachakan , Thomas Langø , Ole-Jakob Elle , Frank Lindseth

Diffusion-based unsupervised image registration has been explored for cardiac cine MR, but expensive multi-step inference limits practical use. We propose FlowReg, a flow-matching framework in displacement field space that achieves strong…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Yunguan Fu , Wenjia Bai , Wen Yan , Matthew J Clarkson , Rhodri Huw Davies , Yipeng Hu

Automated endoscopy video analysis is a challenging task in medical computer vision, with the primary objective of assisting surgeons during procedures. The difficulty arises from the complexity of surgical scenes and the lack of a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Dominik Batić , Felix Holm , Ege Özsoy , Tobias Czempiel , Nassir Navab

Dynamic contrast-enhanced (DCE) cardiac magnetic resonance imaging (CMRI) is a widely used modality for diagnosing myocardial blood flow (perfusion) abnormalities. During a typical free-breathing DCE-CMRI scan, close to 300 time-resolved…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Dilek M. Yalcinkaya , Khalid Youssef , Bobak Heydari , Orlando Simonetti , Rohan Dharmakumar , Subha Raman , Behzad Sharif

Purpose: Accurate 3D MRI-ultrasound (US) deformable registration is critical for real-time guidance in high-dose-rate (HDR) prostate brachytherapy. We present a weakly supervised spatial implicit neural representation (SINR) method to…

Medical Physics · Physics 2025-03-19 Jing Wang , Ruirui Liu , Yu Lei , Michael J. Baine , Tian Liu , Yang Lei

We introduce an unsupervised motion-compensated image reconstruction algorithm for free-breathing and ungated 3D cardiac magnetic resonance imaging (MRI). We express the image volume corresponding to each specific motion phase as the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Joseph Kettelkamp , Ludovica Romanin , Sarv Priya , Mathews Jacob

Accurate segmentation of cardiac structures in cardiovascular magnetic resonance (CMR) images is essential for reliable diagnosis and treatment of cardiovascular diseases. However, manual segmentation remains time-consuming and suffers from…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Ujjwal Jain

Accurate registration of medical images is vital for doctor's diagnosis and quantitative analysis. In this paper, we propose a new deformable medical image registration method based on average geometric transformations and VoxelMorph CNN…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Yongpei Zhu , Zicong Zhou , Guojun Liao , Kehong Yuan

Image-guided surgery collocates patient-specific data with the physical environment to facilitate surgical decision making in real-time. Unfortunately, these guidance systems commonly become compromised by intraoperative soft-tissue…

Image and Video Processing · Electrical Eng. & Systems 2023-06-12 Morgan Ringel , Jon Heiselman , Winona Richey , Ingrid Meszoely , William Jarnagin , Michael Miga

Image registration is used in many medical image analysis applications, such as tracking the motion of tissue in cardiac images, where cardiac kinematics can be an indicator of tissue health. Registration is a challenging problem for deep…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Benjamin Graham

Digital image correlation (DIC) has become one of the most popular methods for deformation characterization in experimental mechanics. DIC is based on optical images taken during experimentation and post-test image processing. Its…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Ravi Venkata Surya Sai Mogilisetti , Partha Pratim Das , Rassel Raihan , Shiyao Lin

With this work, we release CLAIRE, a distributed-memory implementation of an effective solver for constrained large deformation diffeomorphic image registration problems in three dimensions. We consider an optimal control formulation. We…

Optimization and Control · Mathematics 2020-09-01 Andreas Mang , Amir Gholami , Christos Davatzikos , George Biros