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The success of precision medicine requires computational models that can effectively process and interpret diverse physiological signals across heterogeneous patient populations. While foundation models have demonstrated remarkable transfer…

Machine Learning · Computer Science 2024-12-05 Matthias Christenson , Cove Geary , Brian Locke , Pranav Koirala , Warren Woodrich Pettine

Foundation models (FMs) have transformed computational pathology by providing powerful, general-purpose feature extractors. However, adapting and benchmarking individual FMs for specific diagnostic tasks is often time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Peiran Quan , Zifan Gu , Zhuo Zhao , Qin Zhou , Donghan M. Yang , Ruichen Rong , Yang Xie , Guanghua Xiao

The biological behavior and treatment response of meningiomas depend on their grade, making an accurate diagnosis essential for treatment planning and prognosis assessment. We observed that the weighted fusion of spatial-frequency domain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Jiamiao Lu , Wei Wu , Ke Gao , Ping Mao , Weichuan Zhang , Tuo Wang , Lingkun Ma , Jiapan Guo , Zanyi Wu , Yuqing Hu , Changming Sun

The growing reliance on deep learning models in safety-critical domains such as healthcare and autonomous navigation underscores the need for defenses that are both robust to adversarial perturbations and transparent in their…

Machine Learning · Computer Science 2026-01-06 Longwei Wang , Mohammad Navid Nayyem , Abdullah Al Rakin , KC Santosh , Chaowei Zhang , Yang Zhou

Microbiome data analysis is essential for understanding host health and disease, yet its inherent sparsity and noise pose major challenges for accurate imputation, hindering downstream tasks such as biomarker discovery. Existing imputation…

Machine Learning · Computer Science 2025-08-01 Rabeya Tus Sadia , Qiang Cheng

Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Instead of building…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Mohammad Areeb Qazi , Munachiso S Nwadike , Ibrahim Almakky , Mohammad Yaqub , Numan Saeed

Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundation models in downstream tasks efficiently…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Dequan Wang , Xiaosong Wang , Lilong Wang , Mengzhang Li , Qian Da , Xiaoqiang Liu , Xiangyu Gao , Jun Shen , Junjun He , Tian Shen , Qi Duan , Jie Zhao , Kang Li , Yu Qiao , Shaoting Zhang

Pathology foundation models (PFMs) have enabled robust generalization in computational pathology through large-scale datasets and expansive architectures, but their substantial computational cost, particularly for gigapixel whole slide…

Recently natural language processing (NLP) tools have been developed to identify and extract salient risk indicators in electronic health records (EHRs). Sentiment analysis, although widely used in non-medical areas for improving decision…

Computation and Language · Computer Science 2019-04-09 Eben Holderness , Philip Cawkwell , Kirsten Bolton , James Pustejovsky , Mei-Hua Hall

Recently reconstruction-based deep models have been widely used for time series anomaly detection, but as their capacity and generalization capability increase, these models tend to over-generalize, often reconstructing unseen anomalies…

Machine Learning · Computer Science 2026-01-30 Samuel Yoon , Jongwon Kim , Juyoung Ha , Young Myoung Ko

Automatic pneumonia Detection based on deep learning has increasing clinical value. Although the existing Feature Pyramid Network (FPN) and its variants have already achieved some great successes, their detection accuracies for pneumonia…

Image and Video Processing · Electrical Eng. & Systems 2020-11-18 Xudong Zhang , Bo Wang , Di Yuan , Zhenghua Xu , Guizhi Xu

To evaluate the translational capabilities of foundation models, we develop a pathological concept learning approach focused on kidney cancer. By leveraging TNM staging guidelines and pathology reports, we build comprehensive pathological…

Artificial Intelligence · Computer Science 2025-10-01 Shangqi Gao , Sihan Wang , Yibo Gao , Boming Wang , Xiahai Zhuang , Anne Warren , Grant Stewart , James Jones , Mireia Crispin-Ortuzar

Deep learning based methods for medical images can be easily compromised by adversarial examples (AEs), posing a great security flaw in clinical decision-making. It has been discovered that conventional adversarial attacks like PGD which…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Qingsong Yao , Zecheng He , Yuexiang Li , Yi Lin , Kai Ma , Yefeng Zheng , S. Kevin Zhou

Accurate segmentation of tumors and adjacent normal tissues in medical images is essential for surgical planning and tumor staging. Although foundation models generally perform well in segmentation tasks, they often struggle to focus on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Kai Han , Siqi Ma , Chengxuan Qian , Jun Chen , Chongwen Lyu , Yuqing Song , Zhe Liu

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). Existing approaches typically rely on frozen pre-trained models to extract instance features, neglecting the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Yi Lin , Zhengjie Zhu , Kwang-Ting Cheng , Hao Chen

Domain adaptive detection aims to improve the generalization of detectors on target domain. To reduce discrepancy in feature distributions between two domains, recent approaches achieve domain adaption through feature alignment in different…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Libo Zhang , Wenzhang Zhou , Heng Fan , Tiejian Luo , Haibin Ling

This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry datasets. We compare 13 feature extractor models, including…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Amaya Gallagher-Syed , Elena Pontarini , Myles J. Lewis , Michael R. Barnes , Gregory Slabaugh

Fetal ultrasound standard plane classification is essential for reliable prenatal diagnosis but faces inherent challenges, including low tissue contrast, boundary ambiguity, and operator-dependent image quality variations. To overcome these…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Yang Chen , Sanglin Zhao , Baoyu Chen , Mans Gustaf

In medical contexts, the imbalanced data distribution in long-tailed datasets, due to scarce labels for rare diseases, greatly impairs the diagnostic accuracy of deep learning models. Recent multimodal text-image supervised foundation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Sirui Li , Li Lin , Yijin Huang , Pujin Cheng , Xiaoying Tang

Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Pablo Meseguer , Rocío del Amor , Adrian Colomer , Valery Naranjo