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Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

Multiple-instance learning (MIL) is an attractive approach for digital pathology applications as it reduces the costs related to data collection and labelling. However, it is not clear how sensitive MIL is to clinically realistic domain…

Computer Vision and Pattern Recognition · Computer Science 2024-05-17 Milda Pocevičiūtė , Gabriel Eilertsen , Stina Garvin , Claes Lundström

This paper focuses on learning transferable adversarial examples specifically against defense models (models to defense adversarial attacks). In particular, we show that a simple universal perturbation can fool a series of state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2020-08-03 Yingwei Li , Song Bai , Cihang Xie , Zhenyu Liao , Xiaohui Shen , Alan L. Yuille

Foundation models trained on large-scale pathology image corpora have demonstrated strong transfer capabilities across diverse histopathology tasks. Building on this progress, we introduce PLUTO-4, our next generation of pathology…

Foundation models have recently emerged as powerful feature extractors in computational pathology, yet they typically omit mechanisms for leveraging the global spatial structure of tissues and the local contextual relationships among…

Mitosis detection in histopathology images plays a key role in tumor assessment. Although machine learning algorithms could be exploited for aiding physicians in accurately performing such a task, these algorithms suffer from significative…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Gennaro Percannella , Mattia Sarno , Francesco Tortorella , Mario Vento

Face recognition (FR) models can be easily fooled by adversarial examples, which are crafted by adding imperceptible perturbations on benign face images. The existence of adversarial face examples poses a great threat to the security of…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Fengfan Zhou , Hefei Ling , Yuxuan Shi , Jiazhong Chen , Zongyi Li , Ping Li

Deep learning models for dermatological image analysis remain sensitive to acquisition variability and domain-specific visual characteristics, leading to performance degradation when deployed in clinical settings. We investigate how visual…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Rodrigo Mota , Kelvin Cunha , Emanoel dos Santos , Fábio Papais , Francisco Filho , Thales Bezerra , Erico Medeiros , Paulo Borba , Tsang Ing Ren

Background and objective: Prior probability shift between training and deployment datasets challenges deep learning-based medical image classification. Standard correction methods reweight posterior probabilities to adjust prior bias, yet…

Quantitative Methods · Quantitative Biology 2025-11-06 Takaaki Tachibana , Toru Nagasaka , Yukari Adachi , Hiroki Kagiyama , Ryota Ito , Mitsugu Fujita , Kimihiro Yamashita , Yoshihiro Kakeji

Domain adaptive image retrieval includes single-domain retrieval and cross-domain retrieval. Most of the existing image retrieval methods only focus on single-domain retrieval, which assumes that the distributions of retrieval databases and…

Computer Vision and Pattern Recognition · Computer Science 2020-03-09 Fuxiang Huang , Lei Zhang , Yang Yang , Xichuan Zhou

Machine learning techniques are steadily becoming more important in modern biology, and are used to build predictive models, discover patterns, and investigate biological problems. However, models trained on one dataset are often not…

Quantitative Methods · Quantitative Biology 2024-05-30 Seyedmehdi Orouji , Martin C. Liu , Tal Korem , Megan A. K. Peters

Vision Transformers are at the heart of the current surge of interest in foundation models for histopathology. They process images by breaking them into smaller patches following a regular grid, regardless of their content. Yet, not all…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Clément Grisi , Geert Litjens , Jeroen van der Laak

Source-Free Object Detection (SFOD) aims to adapt a source-pretrained object detector to a target domain without access to source data. However, existing SFOD methods predominantly rely on internal knowledge from the source model, which…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Huizai Yao , Sicheng Zhao , Pengteng Li , Yi Cui , Shuo Lu , Weiyu Guo , Yunfan Lu , Yijie Xu , Hui Xiong

Automatic Medical Imaging Narrative generation aims to alleviate the workload of radiologists by producing accurate clinical descriptions directly from radiological images. However, the subtle visual nuances and domain-specific terminology…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Kai Shu , Yuzhuo Jia , Ziyang Zhang , Jiechao Gao

Understanding point clouds captured from the real-world is challenging due to shifts in data distribution caused by varying object scales, sensor angles, and self-occlusion. Prior works have addressed this issue by combining recent learning…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Joonhyung Park , Hyunjin Seo , Eunho Yang

To tackle the prevalence of pseudo changes, the scarcity of labeled samples, and the difficulty of cross-domain generalization in multi-temporal and multi-source remote sensing imagery, we propose PeftCD, a change detection framework built…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Sijun Dong , Yuxuan Hu , LiBo Wang , Geng Chen , Xiaoliang Meng

Numerous studies have explored image-based automated systems for plant disease diagnosis, demonstrating impressive diagnostic capabilities. However, recent large-scale analyses have revealed a critical limitation: that the diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Shoma Kudo , Satoshi Kagiwada , Hitoshi Iyatomi

Domain shift in the field of histopathological imaging is a common phenomenon due to the intra- and inter-hospital variability of staining and digitization protocols. The implementation of robust models, capable of creating generalized…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Ilán Carretero , Pablo Meseguer , Rocío del Amor , Valery Naranjo

Generalizability of deep learning models may be severely affected by the difference in the distributions of the train (source domain) and the test (target domain) sets, e.g., when the sets are produced by different hardware. As a…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Ivan Zakazov , Vladimir Shaposhnikov , Iaroslav Bespalov , Dmitry V. Dylov