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This paper presents a fairness-audited and interpretable machine learning framework for predicting polycystic ovary syndrome (PCOS), designed to evaluate model performance and identify diagnostic disparities across patient subgroups. The…

Machine Learning · Computer Science 2025-11-18 Asma Sadia Khan , Sadia Tabassum

Vascular calcification is implicated as an important factor in major adverse cardiovascular events (MACE), including heart attack and stroke. A controversy remains over how to integrate the diverse forms of vascular calcification into…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Mehdi Ramezanpour , Anne M. Robertson , Yasutaka Tobe , Xiaowei Jia , Juan R. Cebral

Aims. To develop a deep-learning based system for recognition of subclinical atherosclerosis on a plain frontal chest x-ray. Methods and Results. A deep-learning algorithm to predict coronary artery calcium (CAC) score (the AI-CAC model)…

Peripheral Blood Smear (PBS) is a critical microscopic examination in hematopathology that yields whole-slide imaging (WSI). Unlike solid tissue pathology, PBS interpretation focuses on individual cell morphologies rather than tissue…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Yuanlong Wang , Weichi Chen , Adrian Rajab , Wenfang Liu , Yulan Jin , Andrew Srisuwananukorn , Ping Zhang

Ultrasound Localization Microscopy (ULM) can map microvessels at a resolution of a few micrometers (\mu m). Transcranial ULM remains challenging in presence of aberrations caused by the skull, which lead to localization errors. Herein, we…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Paul Xing , Jonathan Porée , Brice Rauby , Antoine Malescot , Éric Martineau , Vincent Perrot , Ravi L. Rungta , Jean Provost

Perivascular Spaces (PVS) are a recently recognised feature of Small Vessel Disease (SVD), also indicating neuroinflammation, and are an important part of the brain's circulation and glymphatic drainage system. Quantitative analysis of PVS…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Lucia Ballerini , Ruggiero Lovreglio , Maria del C. Valdes-Hernandez , Joel Ramirez , Bradley J. MacIntosh , Sandra E. Black , Joanna M. Wardlaw

Atrial fibrillation (AF) is associated with an increased risk of dementia and cognitive decline, independent of strokes. Several mechanisms have been proposed to explain this association, but altered cerebral blood flow dynamics during AF…

Medical Physics · Physics 2016-06-24 Matteo Anselmino , Stefania Scarsoglio , Andrea Saglietto , Fiorenzo Gaita , Luca Ridolfi

An accurate assessment of the cardiovascular system and prediction of cardiovascular diseases (CVDs) are crucial. Measured cardiac blood flow data provide insights about patient-specific hemodynamics, where many specialized techniques have…

Estimating clinically-relevant vascular features following vessel segmentation is a standard pipeline for retinal vessel analysis, which provides potential ocular biomarkers for both ophthalmic disease and systemic disease. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Yukun Zhou , Moucheng Xu , Yipeng Hu , Stefano B. Blumberg , An Zhao , Siegfried K. Wagner , Pearse A. Keane , Daniel C. Alexander

Cerebral aneurysm progression is a result of a complex interplay of the biomechanical and clinical risk factors that drive aneurysmal growth and rupture. Subjects with multiple aneurysms are unique cases wherein clinical risk factors are…

Medical Physics · Physics 2022-12-26 Tanmay C. Shidhore , Aaron A. Cohen-Gadol , Vitaliy L. Rayz , Ivan C. Christov

Prenatal ultrasound evaluates fetal growth and detects congenital abnormalities during pregnancy, but the examination of ultrasound images by radiologists requires expertise and sophisticated equipment, which would otherwise fail to improve…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Yang Qi , Jiaxin Cai , Jing Lu , Runqing Xiong , Rongshang Chen , Liping Zheng , Duo Ma

Predicting breast cancer recurrence risk is a critical clinical challenge. This study investigates the potential of computational pathology to stratify patients using deep learning on routine Hematoxylin and Eosin (H&E) stained whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Jinqiu Chen , Huyan Xu

Brain aging is a regional phenomenon, a facet that remains relatively under-explored within the realm of brain age prediction research using machine learning methods. Voxel-level predictions can provide localized brain age estimates that…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Neha Gianchandani , Mahsa Dibaji , Johanna Ospel , Fernando Vega , Mariana Bento , M. Ethan MacDonald , Roberto Souza

4D Flow MRI is the state of the art technique for measuring blood flow, and it provides valuable information for inverse problems in the cardiovascular system. However, 4D Flow MRI has a very long acquisition time, straining healthcare…

Numerical Analysis · Mathematics 2025-12-09 Miriam Löcke , Pim van Ooij , Cristóbal Bertoglio

During the first years of life, the human brain undergoes dynamic spatially-heterogeneous changes, involving differentiation of neuronal types, dendritic arborization, axonal ingrowth, outgrowth and retraction, synaptogenesis, and…

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…

Objective: Hydrocephalus is a medical condition in which there is an abnormal accumulation of cerebrospinal fluid (CSF) in the brain. Segmentation of brain imagery into brain tissue and CSF (before and after surgery, i.e. pre-op vs. postop)…

Image and Video Processing · Electrical Eng. & Systems 2018-09-11 Venkateswararao Cherukuri , Peter Ssenyonga , Benjamin C. Warf , Abhaya V. Kulkarni , Vishal Monga , Steven J. Schiff

Super-resolution ultrasound (SRUS) imaging through localising and tracking sparse microbubbles has been shown to reveal microvascular structure and flow beyond the wave diffraction limit. Most SRUS studies use standard delay and sum (DAS)…

Purpose: To develop biophysics-based method for estimating perfusion Q from arterial spin labeling (ASL) images using deep learning. Methods: A 3D U-Net (QTMnet) was trained to estimate perfusion from 4D tracer propagation images. The…

Quantitative Methods · Quantitative Biology 2023-11-20 Renjiu Hu , Qihao Zhang , Pascal Spincemaille , Thanh D. Nguyen , Yi Wang

We applied several regression and deep learning methods to predict fluid intelligence scores from T1-weighted MRI scans as part of the ABCD Neurocognitive Prediction Challenge (ABCD-NP-Challenge) 2019. We used voxel intensities and…