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The growing complexity of healthcare systems requires advanced computational models for real-time monitoring, secure data exchange, and intelligent decision-making. Digital Twins (DTs) provide virtual representations of physical healthcare…

Emerging Technologies · Computer Science 2026-02-18 Asma Taheri Monfared , Andrea Bombarda , Angelo Gargantini , Majid Haghparast

Chronic diseases constitute the principal burden of morbidity, mortality, and healthcare costs worldwide, yet current health systems remain fragmented and predominantly reactive. Patient Medical Digital Twins (PMDTs) offer a paradigm shift:…

Software Engineering · Computer Science 2026-02-13 Micheal P. Papazoglou , Bernd J. Krämer , Mira Raheem , Amal Elgammal

A Digital Twin (DT) is a virtual replica of a physical object or system, created to monitor, analyze, and optimize its behavior and characteristics. A Spatial Digital Twin (SDT) is a specific type of digital twin that emphasizes the…

Computers and Society · Computer Science 2023-06-13 Mohammed Eunus Ali , Muhammad Aamir Cheema , Tanzima Hashem , Anwaar Ulhaq , Muhammad Ali Babar

Digital twins (DT) are often defined as a pairing of a physical entity and a corresponding virtual entity (VE), mimicking certain aspects of the former depending on the use-case. In recent years, this concept has facilitated numerous…

Recent developments in Artificial Intelligence (AI) and Machine Learning (ML) are creating new opportunities for Human-Autonomy Teaming (HAT) in tasks, missions, and continuous coordinated activities. A major challenge is enabling humans to…

Human-Computer Interaction · Computer Science 2025-04-07 Abdul Mannan Mohammed , Azhar Ali Mohammad , Jason A. Ortiz , Carsten Neumann , Grace Bochenek , Dirk Reiners , Carolina Cruz-Neira

As collaborative robot (Cobot) adoption in many sectors grows, so does the interest in integrating digital twins in human-robot collaboration (HRC). Virtual representations of physical systems (PT) and assets, known as digital twins, can…

Robotics · Computer Science 2023-11-07 Mohamad Shaaban , Alessandro Carfì , Fulvio Mastrogiovanni

Medical imaging has played a pivotal role in advancing and refining digital twin technology, allowing for the development of highly personalized virtual models that represent human anatomy and physiological functions. A key component in…

Medical Physics · Physics 2024-11-14 Feng Zhao , Yizhou Wu , Mingzhe Hu , Chih-Wei Chang , Ruirui Liu , Richard Qiu , Xiaofeng Yang

After Big Data and Artificial Intelligence (AI), the subject of Digital Twins has emerged as another promising technology, advocated, built, and sold by various IT companies. The approach aims to produce highly realistic models of real…

Physics and Society · Physics 2023-09-11 Dirk Helbing , Javier Argota Sánchez-Vaquerizo

Digital Twins (DTs) are becoming increasingly vital for future industrial applications, enhancing monitoring, control, and optimization of physical assets. This enhancement is made possible by integrating various Digital Models (DMs) within…

Optical communication is developing rapidly in the directions of hardware resource diversification, transmission system flexibility, and network function virtualization. Its proliferation poses a significant challenge to traditional optical…

Networking and Internet Architecture · Computer Science 2020-11-11 Danshi Wang , Zhiguo Zhang , Min Zhang , Meixia Fu , Jin Li , Shanyong Cai , Chunyu Zhang , Xue Chen

Digital Twins (DT) are essentially dynamic data-driven models that serve as real-time symbiotic "virtual replicas" of real-world systems. DT can leverage fundamentals of Dynamic Data-Driven Applications Systems (DDDAS) bidirectional…

Artificial Intelligence · Computer Science 2024-02-01 Nan Zhang , Rami Bahsoon , Nikos Tziritas , Georgios Theodoropoulos

Clinical trials are indispensable for medical research and the development of new treatments. However, clinical trials often involve thousands of participants and can span several years to complete, with a high probability of failure during…

Machine Learning · Computer Science 2024-07-02 Yue Wang , Tianfan Fu , Yinlong Xu , Zihan Ma , Hongxia Xu , Yingzhou Lu , Bang Du , Honghao Gao , Jian Wu

This article presents a vision where \textit{real-time} digital twins of the physical wireless environments are continuously updated using multi-modal sensing data from the distributed infrastructure and user devices, and are used to make…

Signal Processing · Electrical Eng. & Systems 2023-01-27 Ahmed Alkhateeb , Shuaifeng Jiang , Gouranga Charan

Mobile Artificial Intelligence-Generated Content (AIGC) technology refers to the adoption of AI algorithms deployed at mobile edge networks to automate the information creation process while fulfilling the requirements of end users. Mobile…

Networking and Internet Architecture · Computer Science 2023-07-25 Jiayuan Chen , Changyan Yi , Hongyang Du , Dusit Niyato , Jiawen Kang , Jun Cai , Xuemin , Shen

Smart Digital twins (SDTs) are being increasingly used to virtually replicate and predict the behaviors of complex physical systems through continual data assimilation enabling the optimization of the performance of these systems by…

Computer Vision and Pattern Recognition · Computer Science 2024-01-08 Md Ruman Islam , Mahadevan Subramaniam , Pei-Chi Huang

The Digital Twins (DT) has quickly become a hot topic since it was proposed. It not only appears in all kinds of commercial propaganda, but also is widely quoted by academic circles. However, there are misstatements and misuse of the term…

Computational Engineering, Finance, and Science · Computer Science 2022-03-25 Jiehan Zhou , Shouhua Zhang , Mu Gu

Digital Twin (DT) has gained great interest as an innovative technology in Industry 4.0 that enables advanced modeling, simulation, and optimization of service and manufacturing systems. This article provides an extensive review of the…

General Mathematics · Mathematics 2026-01-26 Sarow Saeedi

Although Digital Twin is actively deployed in manufacturing, its human-centric counterpart - Human Digital Twin (HDT) is understudied, especially in job-shop production with high task variability and manual labor. HDT applications like…

Other Computer Science · Computer Science 2025-11-21 Samiran Sardar , Nasif Morshed , Shezan Ahmed

The vision of personalized medicine is to identify interventions that maintain or restore a person's health based on their individual biology. Medical digital twins, computational models that integrate a wide range of health-related data…

Quantitative Methods · Quantitative Biology 2025-10-21 Luis L. Fonseca , Lucas Böttcher , Borna Mehrad , Reinhard C. Laubenbacher

A digital twin can be defined as an adaptive model of a complex physical system. Recent advances in computational pipelines, multiphysics solvers, artificial intelligence, big data cybernetics, data processing and management tools bring the…

Signal Processing · Electrical Eng. & Systems 2019-10-07 Adil Rasheed , Omer San , Trond Kvamsdal