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Related papers: Ontology-Guided Query Expansion for Biomedical Doc…

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Knowledge graphs and large language models (LLMs) are key tools for biomedical knowledge integration and reasoning, facilitating structured organization of scientific articles and discovery of complex semantic relationships. However,…

Computation and Language · Computer Science 2025-04-01 Yichun Feng , Jiawei Wang , Ruikun He , Lu Zhou , Yixue Li

Retrieval-augmented generation (RAG) mitigates hallucination in Large Language Models (LLMs) by using query pipelines to retrieve relevant external information and grounding responses in retrieved knowledge. However, query pipeline…

Computation and Language · Computer Science 2026-04-17 Maolin He , Rena Gao , Mike Conway , Brian E. Chapman

Large language models (LLMs) have shown impressive prowess in solving a wide range of tasks with world knowledge. However, it remains unclear how well LLMs are able to perceive their factual knowledge boundaries, particularly under…

Computation and Language · Computer Science 2024-11-20 Ruiyang Ren , Yuhao Wang , Yingqi Qu , Wayne Xin Zhao , Jing Liu , Hao Tian , Hua Wu , Ji-Rong Wen , Haifeng Wang

In today's digital world, seeking answers to health questions on the Internet is a common practice. However, existing question answering (QA) systems often rely on using pre-selected and annotated evidence documents, thus making them…

Computation and Language · Computer Science 2024-04-15 Juraj Vladika , Florian Matthes

Recent advances in large language models (LLMs) have made significant progress across multiple biomedical tasks, including biomedical question answering, lay-language summarization of the biomedical literature, and clinical note…

Information Retrieval · Computer Science 2026-03-24 Deepak Gupta , Dina Demner-Fushman , William Hersh , Steven Bedrick , Kirk Roberts

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

Search-augmented large language models (LLMs) excel at knowledge-intensive tasks by integrating external retrieval. However, they often over-search -- unnecessarily invoking search tool even when it does not improve response quality, which…

Machine Learning · Computer Science 2026-03-12 Roy Xie , Deepak Gopinath , David Qiu , Dong Lin , Haitian Sun , Saloni Potdar , Bhuwan Dhingra

Traditional information retrieval (IR) methods excel at textual and semantic matching but struggle in reasoning-intensive retrieval tasks that require multi-hop inference or complex semantic understanding between queries and documents. One…

Information Retrieval · Computer Science 2025-06-17 Xubo Qin , Jun Bai , Jiaqi Li , Zixia Jia , Zilong Zheng

In this study, we investigate the potential of Large Language Models to complement biomedical knowledge graphs in the training of semantic models for the biomedical and clinical domains. Drawing on the wealth of the UMLS knowledge graph and…

Computation and Language · Computer Science 2023-11-28 François Remy , Kris Demuynck , Thomas Demeester

Large Language Models (LLMs) have exhibited impressive generation capabilities, but they suffer from hallucinations when solely relying on their internal knowledge, especially when answering questions that require less commonly known…

Computation and Language · Computer Science 2023-11-01 Wenting Zhao , Ye Liu , Tong Niu , Yao Wan , Philip S. Yu , Shafiq Joty , Yingbo Zhou , Semih Yavuz

Query expansion aims to mitigate the mismatch between the language used in a query and in a document. However, query expansion methods can suffer from introducing non-relevant information when expanding the query. To bridge this gap,…

Information Retrieval · Computer Science 2020-11-04 Zhi Zheng , Kai Hui , Ben He , Xianpei Han , Le Sun , Andrew Yates

Accurate recognition of biomedical named entities is critical for medical information extraction and knowledge discovery. However, existing methods often struggle with nested entities, entity boundary ambiguity, and cross-lingual…

Computation and Language · Computer Science 2025-10-13 Tengxiao Lv , Ling Luo , Juntao Li , Yanhua Wang , Yuchen Pan , Chao Liu , Yanan Wang , Yan Jiang , Huiyi Lv , Yuanyuan Sun , Jian Wang , Hongfei Lin

Linking (aligning) biomedical concepts across diverse data sources enables various integrative analyses, but it is challenging due to the discrepancies in concept naming conventions. Various strategies have been developed to overcome this…

Information Retrieval · Computer Science 2024-05-14 Yuzhang Xie , Jiaying Lu , Joyce Ho , Fadi Nahab , Xiao Hu , Carl Yang

Automatic relationship extraction (RE) from biomedical literature is critical for managing the vast amount of scientific knowledge produced each year. In recent years, utilizing pre-trained language models (PLMs) has become the prevalent…

Computation and Language · Computer Science 2025-11-04 Mario Sänger , Ulf Leser

Prompt engineering significantly influences the reliability and clinical utility of Large Language Models (LLMs) in medical applications. Current optimization approaches inadequately address domain-specific medical knowledge and safety…

Computation and Language · Computer Science 2025-08-26 Yinda Chen , Yangfan He , Jing Yang , Dapeng Zhang , Zhenlong Yuan , Muhammad Attique Khan , Jamel Baili , Por Lip Yee

Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is…

Computation and Language · Computer Science 2024-07-09 Bojana Bašaragin , Adela Ljajić , Darija Medvecki , Lorenzo Cassano , Miloš Košprdić , Nikola Milošević

This research paper discusses the advances made in the past decade in biomedicine and Large Language Models. To understand how the advances have been made hand-in-hand with one another, the paper also discusses the integration of Natural…

Computation and Language · Computer Science 2024-06-26 Michael Ackerman

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

CQA services are valuable sources of knowledge that can be used to find answers to users' information needs. In these services, question retrieval aims to help users with their information needs by finding similar questions to theirs.…

Information Retrieval · Computer Science 2024-11-26 Yasin Ghafourian , Sajad Movahedi , Azadeh Shakery

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov
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