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Related papers: Ontology-Guided Query Expansion for Biomedical Doc…

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Large language models (LLMs)-based query expansion for information retrieval augments queries with generated hypothetical documents with LLMs. However, its performance relies heavily on the scale of the language models (LMs), necessitating…

Information Retrieval · Computer Science 2025-06-10 Lingyuan Liu , Mengxiang Zhang

We present BioLunar, developed using the Lunar framework, as a tool for supporting biological analyses, with a particular emphasis on molecular-level evidence enrichment for biomarker discovery in oncology. The platform integrates Large…

Recent studies have proposed leveraging Large Language Models (LLMs) as information retrievers through query rewriting. However, for challenging corpora, we argue that enhancing queries alone is insufficient for robust semantic matching;…

Information Retrieval · Computer Science 2025-06-24 Jingming Liu , Yumeng Li , Wei Shi , Yao-Xiang Ding , Hui Su , Kun Zhou

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…

Computation and Language · Computer Science 2024-08-19 Yucheng Shi , Shaochen Xu , Tianze Yang , Zhengliang Liu , Tianming Liu , Quanzheng Li , Xiang Li , Ninghao Liu

Large Language Models (LLMs) with reasoning capabilities have recently demonstrated strong potential in medical Question Answering (QA). Existing approaches are largely English-focused and primarily rely on distillation from general-purpose…

Computation and Language · Computer Science 2026-03-31 Pietro Ferrazzi , Aitor Soroa , Rodrigo Agerri

Recent advances in the healthcare industry have led to an abundance of unstructured data, making it challenging to perform tasks such as efficient and accurate information retrieval at scale. Our work offers an all-in-one scalable solution…

Information Retrieval · Computer Science 2023-02-15 Shreya Saxena , Raj Sangani , Siva Prasad , Shubham Kumar , Mihir Athale , Rohan Awhad , Vishal Vaddina

Large language models (LLMs) have demonstrated significant potential in enhancing dense retrieval through query augmentation. However, most existing methods treat the LLM and the retriever as separate modules, overlooking the alignment…

Information Retrieval · Computer Science 2025-05-30 Sijia Yao , Pengcheng Huang , Zhenghao Liu , Yu Gu , Yukun Yan , Shi Yu , Ge Yu

To address the requirement of enabling a comprehensive perspective of life-sciences data, Semantic Web technologies have been adopted for standardized representations of data and linkages between data. This has resulted in data warehouses…

Databases · Computer Science 2016-02-03 HyeongSik Kim , Kemafor Anyanwu

Keyword based search engines have problems with term ambiguity and vocabulary mismatch. In this paper, we propose a query expansion technique that enriches queries expressed as keywords and short natural language descriptions. We present a…

Information Retrieval · Computer Science 2013-10-23 Joan Guisado-Gámez , David Dominguez-Sal , Josep-LLuis Larriba-Pey

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

Computation and Language · Computer Science 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Query Expansion (QE) improves retrieval performance by enriching queries with related terms. Recently, Large Language Models (LLMs) have been used for QE, but existing methods face a trade-off: generating diverse terms boosts performance…

Information Retrieval · Computer Science 2025-09-03 Jinseok Kim , Sukmin Cho , Soyeong Jeong , Sangyeop Kim , Sungzoon Cho

Effective query expansion for web search benefits from promoting both exploration and result diversity to capture multiple interpretations and facets of a query. While recent LLM-based methods have improved retrieval performance and…

Information Retrieval · Computer Science 2026-03-11 Yibin Lei , Tao Shen , Andrew Yates

Biomedical question-answering (QA) systems require effective retrieval and generation components to ensure accuracy, efficiency, and scalability. This study systematically examines a Retrieval-Augmented Generation (RAG) system for…

Information Retrieval · Computer Science 2026-01-14 Linus Stuhlmann , Michael Alexander Saxer , Jonathan Fürst

This work presents a Biomedical Literature Question Answering (Q&A) system based on a Retrieval-Augmented Generation (RAG) architecture, designed to improve access to accurate, evidence-based medical information. Addressing the shortcomings…

Computation and Language · Computer Science 2025-09-09 Mansi Garg , Lee-Chi Wang , Bhavesh Ghanchi , Sanjana Dumpala , Shreyash Kakde , Yen Chih Chen

The paper introduces a framework for the evaluation of the encoding of factual scientific knowledge, designed to streamline the manual evaluation process typically conducted by domain experts. Inferring over and extracting information from…

Computation and Language · Computer Science 2024-10-21 Magdalena Wysocka , Oskar Wysocki , Maxime Delmas , Vincent Mutel , Andre Freitas

Retrieval augmented language models have recently become the standard for knowledge intensive tasks. Rather than relying purely on latent semantics within the parameters of large neural models, these methods enlist a semi-parametric memory…

Computation and Language · Computer Science 2023-01-24 Wenhu Chen , Pat Verga , Michiel de Jong , John Wieting , William Cohen

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Despite their general capabilities, LLMs still struggle on biomedical NER tasks, which are difficult due to the presence of specialized terminology and lack of training data. In this work we set out to improve LLM performance on biomedical…

Computation and Language · Computer Science 2024-04-24 Monica Munnangi , Sergey Feldman , Byron C Wallace , Silvio Amir , Tom Hope , Aakanksha Naik

Large Language Models (LLMs) have demonstrated a remarkable potential in medical knowledge acquisition and question-answering. However, LLMs can potentially hallucinate and yield factually incorrect outcomes, even with domain-specific…

Computation and Language · Computer Science 2024-07-01 Junda Wang , Zhichao Yang , Zonghai Yao , Hong Yu