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Microbiome functions are encoded within the genes of the community-wide metagenome. A natural question is whether properties of a microbial community can be predicted just from knowing the raw DNA sequences of its members. In this work, we…

Genomics · Quantitative Biology 2026-05-13 Younhun Kim , Georg K. Gerber , Travis E. Gibson

Accurate estimates of microbial species abundances are needed to advance our understanding of the role that microbiomes play in human and environmental health. However, artificially constructed microbiomes demonstrate that intuitive…

Methodology · Statistics 2025-03-17 David S Clausen , Amy D Willis

Metagenomic disease prediction commonly relies on species abundance tables derived from large, incomplete reference catalogs, constraining resolution and discarding valuable information contained in DNA reads. To overcome these limitations,…

Genomics · Quantitative Biology 2026-01-08 Gaspar Roy , Eugeni Belda , Baptiste Hennecart , Yann Chevaleyre , Edi Prifti , Jean-Daniel Zucker

Effective representation of data is crucial in various machine learning tasks, as it captures the underlying structure and context of the data. Embeddings have emerged as a powerful technique for data representation, but evaluating their…

Machine Learning · Computer Science 2023-09-21 Sarwan Ali

Modern large language models (LLMs) excel at tasks that require storing and retrieving knowledge, such as factual recall and question answering. Transformers are central to this capability because they can encode information during training…

Machine Learning · Statistics 2026-03-18 Nuri Mert Vural , Alberto Bietti , Mahdi Soltanolkotabi , Denny Wu

We propose a method to facilitate exploration and analysis of new large data sets. In particular, we give an unsupervised deep learning approach to learning a latent representation that captures semantic similarity in the data set. The core…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Gary B Huang , Huei-Fang Yang , Shin-ya Takemura , Pat Rivlin , Stephen M Plaza

This paper reports, by way of introduction, on the advances made by our group and the broader signal processing community on the concept of sample abundance; a phenomenon that naturally arises in one-bit and few-bit signal processing…

Information Theory · Computer Science 2025-07-28 Arian Eamaz , Farhang Yeganegi , Mojtaba Soltanalian

Transformer models, which leverage architectural improvements like self-attention, perform remarkably well on Natural Language Processing (NLP) tasks. The self-attention mechanism is position agnostic. In order to capture positional…

Computation and Language · Computer Science 2021-09-28 Zhiheng Huang , Davis Liang , Peng Xu , Bing Xiang

Sequence classification is the supervised learning task of building models that predict class labels of unseen sequences of symbols. Although accuracy is paramount, in certain scenarios interpretability is a must. Unfortunately, such…

Machine Learning · Computer Science 2020-06-26 Severin Gsponer , Luca Costabello , Chan Le Van , Sumit Pai , Christophe Gueret , Georgiana Ifrim , Freddy Lecue

Metagenomic studies have increasingly utilized sequencing technologies in order to analyze DNA fragments found in environmental samples.One important step in this analysis is the taxonomic classification of the DNA fragments. Conventional…

Genomics · Quantitative Biology 2020-02-11 Andreas Georgiou , Vincent Fortuin , Harun Mustafa , Gunnar Rätsch

Large-scale multi-relational embedding refers to the task of learning the latent representations for entities and relations in large knowledge graphs. An effective and scalable solution for this problem is crucial for the true success of…

Machine Learning · Computer Science 2017-07-07 Hanxiao Liu , Yuexin Wu , Yiming Yang

This paper proposes a general interpretable predictive system with shared information. The system is able to perform predictions in a multi-task setting where distinct tasks are not bound to have the same input/output structure. Embeddings…

Machine Learning · Computer Science 2024-07-02 Maciej Żelaszczyk , Jacek Mańdziuk

In many real-world applications, modeling both the internal structure of sets and their temporal relationships is essential for capturing complex underlying patterns. Sequential multiple-instance learning aims to address this challenge by…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Athanasios Efthymiou , Stevan Rudinac , Monika Kackovic , Nachoem Wijnberg , Marcel Worring

Deep learning has revolutionized many industries by enabling models to automatically learn complex patterns from raw data, reducing dependence on manual feature engineering. However, deep learning algorithms are sensitive to input data, and…

Machine Learning · Computer Science 2025-07-21 Mert Sehri , Zehui Hua , Francisco de Assis Boldt , Patrick Dumond

Understanding the complex interactions within the microbiome is crucial for developing effective diagnostic and therapeutic strategies. Traditional machine learning models often lack interpretability, which is essential for clinical and…

Machine Learning · Computer Science 2024-10-22 Swagatam Haldar , Christoph Stein-Thoeringer , Vadim Borisov

One critical component in lossy deep image compression is the entropy model, which predicts the probability distribution of the quantized latent representation in the encoding and decoding modules. Previous works build entropy models upon…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Yichen Qian , Ming Lin , Xiuyu Sun , Zhiyu Tan , Rong Jin

Since its introduction, the transformer has shifted the development trajectory away from traditional models (e.g., RNN, MLP) in time series forecasting, which is attributed to its ability to capture global dependencies within temporal…

Machine Learning · Computer Science 2025-01-07 Xiwen Chen , Peijie Qiu , Wenhui Zhu , Huayu Li , Hao Wang , Aristeidis Sotiras , Yalin Wang , Abolfazl Razi

Using a sample from a population to estimate the proportion of the population with a certain category label is a broadly important problem. In the context of microbiome studies, this problem arises when researchers wish to use a sample from…

Methodology · Statistics 2019-02-08 Bryan D. Martin , Daniela Witten , Amy D. Willis

While model architectures and training strategies have become more generic and flexible with respect to different data modalities over the past years, a persistent limitation lies in the assumption of fixed quantities and arrangements of…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Lisa Weijler , Florian Kowarsch , Michael Reiter , Pedro Hermosilla , Margarita Maurer-Granofszky , Michael Dworzak

Many machine learning tasks such as multiple instance learning, 3D shape recognition, and few-shot image classification are defined on sets of instances. Since solutions to such problems do not depend on the order of elements of the set,…

Machine Learning · Computer Science 2019-05-28 Juho Lee , Yoonho Lee , Jungtaek Kim , Adam R. Kosiorek , Seungjin Choi , Yee Whye Teh
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